Prophylaxis News and Research

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Delivering integrated HIV and substance use services through mobile units could save lives

Results from a clinical trial funded by the National Institutes of Health (NIH) in five major United States cities show that delivering integrated HIV and substance use disorder (SUD) services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared to participants who received peer navigation to community-based services alone.

5 Nov 2026

Elusive HIV strains cause breakthrough infections after antibody treatment ends

The broadly neutralizing antibody VRC01 has been thoroughly vetted as a potential prophylactic that could prevent people from becoming infected with HIV.

5 Nov 2026

Clinical trial establishes effective HIV dosing regimen for full-term newborns

An international study conducted through the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Network including researchers at the University of California San Diego helped inform the U.S. Food and Drug Administration's (FDA) recent approval of dolutegravir, a second-generation integrase inhibitor, for the treatment of human immunodeficiency virus (HIV-1) in newborns from birth.

22 Oct 2026

AGA/AASLD joint guideline evaluates newer medications for primary biliary cholangitis

For the first time, a joint guideline from the American Gastroenterological Association (AGA) and American Association for the Study of Liver Diseases (AASLD) evaluates newer medications for primary biliary cholangitis (PBC), the most common cholestatic disease in adults.

22 Oct 2026

Infections caused 1 in 8 cancer cases worldwide in 2024, study finds

Infections drove 1 in 8 cancer cases worldwide in 2024, study finds.

9 Oct 2026

Common anti-epileptic medication shows promise in reducing migraine aura

A new study by researchers at Lund University in Sweden found that 85 percent of patients with aura-dominant migraine experienced a reduction in monthly aura days by at least half following treatment with the anti-epileptic drug lamotrigine.

25 Sep 2026

Chile becomes first South American nation to eliminate dog-transmitted rabies

Chile has become the first country in South America to receive the World Health Organization (WHO) validation for eliminating dog-transmitted rabies as a public health problem.

18 Sep 2026

Persistent stigma creates barriers to modern HIV prevention methods

For decades, HIV (human immunodeficiency virus) has been surrounded by fear, misinformation and stigma.

18 Sep 2026

Low discontinuation rates confirm manageable safety of iza-bren

An investigational EGFR x HER3 antibody-drug conjugate demonstrated promising efficacy with a tolerable safety profile in patients with previously treated EGFR-mutated non-small cell lung cancer (NSCLC), supporting selection of the 2.5 mg/kg dose for evaluation in the global Phase 3 IZABRIGHT-Lung01 registrational study.

12 Sep 2026

Tizanidine looked promising early in a migraine trial, but the benefit did not last

A randomized, double-blind, placebo-controlled trial found that low-dose tizanidine did not provide sustained reductions in headache burden over 12 weeks in people with episodic migraine, despite a transient improvement with the 1 mg dose at week 4. Exploratory analyses suggested that smoking and sex may influence tizanidine exposure, while sex-specific efficacy signals remained hypothesis-generating and require confirmation.

10 Sep 2026

Sexual health education empowers young people to prevent infections

For many adolescents and young adults, life revolves around new experiences, greater independence, and new relationships.

30 Aug 2026

Anti-immigrant policies linked to rising HIV cases among Hispanic populations

Following the Trump administration's 2018 announcement of changes to the public charge rule that would penalize immigrants for using public benefit programs, antisanctuary counties in the US saw a 16.8-percent increase in HIV cases among Hispanic populations, compared to baseline counties.

25 Aug 2026

H5N1 infections remain rare among workers exposed to infected birds

A two-year cohort study of 428 people exposed to H5N1-infected birds in England found fewer than 1% met criteria for infection, with no severe disease or secondary human transmission. The findings support continued PPE use, biosecurity, and targeted surveillance while highlighting challenges around occupational exposure, mucosal contamination, and pandemic preparedness.

10 Aug 2026

Long-acting HIV prevention tools could help close the gap before a vaccine arrives

A review of non-vaccine HIV interventions highlights the strong preventive effects of long-acting PrEP, sustained ART, U=U, vertical transmission programs, and voluntary medical male circumcision. Gene editing and multispecific antibodies may expand future options, but safety, cost, access, adherence, and implementation barriers remain.

5 Aug 2026

Review outlines effective approaches to reduce recurrent hepatic encephalopathy

Hepatic encephalopathy (HE) is a neurologic complication of advanced liver disease, causing impaired functioning, reduced quality of life (QOL), and increased hospitalisation and mortality.

31 Jul 2026

Integration is key to fighting global epidemics, WHO reports

The World Health Organization (WHO) today launched a new report assessing progress in implementing the Global Health Sector Strategies (GHSS) on HIV, viral hepatitis and sexually transmitted infections (STIs) for 2022–2030.

28 Jul 2026

Advanced synthetic grafting material fights bone cancer and prevents infection

Primary bone tumors, such as osteosarcoma, have seen stagnant survival rates over the past four decades. Surgical removal of the tumor is critical, but local recurrence may occur when tumours are close to vital structures, often resulting in amputation.

9 Jul 2026