Protein Engineering News and Research

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Integrated DNA Technologies and Aldevron launch new Cas9 mRNA solutions to accelerate path from gene editing research to development

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

From Integrated DNA Technologies 18 Sep 2026

New AI model maps billions of years of protein evolution

An international team of researchers, including Earth-Life Science Institute (ELSI) at the Institute of Science Tokyo, has developed a protein language model that brings together two fundamental sources of information about proteins: their amino acid sequences and their three-dimensional structures.

11 Sep 2026

New platform enables large-scale production of custom proteins

Scientists have been hard at work for more than 20 years to instruct biological systems, such as E. coli cells, to produce proteins they don't naturally do.

27 Aug 2026

New OpenABE gene editor improves editing efficiency by up to 36 times

A joint research team led by Professor Daesik Kim (Department of Medicine, Sungkyunkwan University), along with Professor Yong-Sub Kim (University of Ulsan College of Medicine) and Professor Jae-Hyun Park (Sungkyunkwan University School of Medicine), has announced the development of 'OpenABE' (Open Adenine Base Editor).

30 Jul 2026

Leerink Partners report names Carterra a core enabler of the $7 B "Lab-in-the-Loop" antibody discovery market

Carterra®, a leading provider of high-throughput surface plasmon resonance (HT-SPR) platforms for antibody and small molecule discovery, today highlighted new research from Leerink Partners identifying Carterra as a key enabling technology in the fast-growing market for AI-driven biologics drug discovery.

From Carterra Inc. 27 Jul 2026

AI redesign helps enzymes evolve beyond natural limits

Researchers showed that AI-redesigned botulinum neurotoxin proteases provided more stable starting points for directed evolution, allowing enzymes to access beneficial mutations that were poorly tolerated in wild-type backgrounds. In BoNT/E models, the approach improved activity, evolvability, and specificity, including an ataxin-2-targeting variant with markedly reduced cleavage of the native SNAP25 substrate.

24 Jul 2026

Fairjourney Bio announces scientific program and leadership for The Antibody Series 2026

FairJourney Bio ("FJBio"), a global antibody discovery expert, has announced the program for The Antibody Series (TAS) 2026, which will explore how insights from natural antibody repertoires, advances in computational design, and novel engineering strategies are transforming the discovery and development of antibody therapeutics.

From FairJourney Biologics 21 Jul 2026

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Frances Arnold on directed enzyme evolution: random mutation plus smart screening, and why it changed enzyme engineering and industry.

From Pittcon 14 Jul 2026

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Professor Heddle's insights on nanobiology and AI highlight their potential to innovate drug delivery and vaccine development, addressing critical health needs.

9 Jun 2026

Sino Biological’s Cell-Free Protein Synthesis supports Tencent AI for Life Sciences Lab’s protein design study published in Nature Communications

Sino Biological, Inc. has announced that its gene synthesis and cell-free protein expression workflow was used in a recent study by Tencent AI for Life Sciences Lab published in Nature Communications, enabling rapid validation of AI-designed proteins with improved activity, stability, and multifunctionality

From Sino Biological Inc. 29 May 2026

MIDAS platform accelerates protein engineering through rapid PCR-based screening

Proteins are critical to life – and to industry. There are countless proteins that could be engineered to treat and even cure serious diseases and cellular dysfunctions.

19 May 2026

ELRIG announces inaugural US drug discovery conference

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, today announced the launch of Drug Discovery USA 2026.

From ELRIG (UK) Ltd. 15 Apr 2026

New method boosts AI-driven protein engineering with massive data

Protein engineering is a field primed for artificial intelligence research. Each protein is made up of amino acids; to optimize a protein function, researchers modify proteins by switching out one of 20 different amino acids for another.

13 Apr 2026

MULTI-evolve accelerates protein engineering with machine learning

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

19 Feb 2026

Thermodynamic insights into histamine H1 receptor ligand binding

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs.

13 Feb 2026

Australian researchers develop a new way to target deadly, drug-resistant bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.

4 Feb 2026

Comprehensive antibody map reveals how SARS-CoV-2 mutations evade immunity

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have created the most comprehensive map to date showing how antibodies attach to the SARS-CoV-2 virus, which causes COVID-19, and how viral mutations weaken that attachment.

21 Nov 2025

New AI investment aims to accelerate the search for an effective HIV vaccine

As of 2024, over 40 million people in the world are diagnosed with human immunodeficiency virus (HIV)-a chronic, life-threatening infection that remains one of the leading global causes of death.

18 Nov 2025

New AI system revolutionizes drug design and vaccine development

The rapid advancement of artificial intelligence (AI) is transforming the field of structural biology. In May 2024, DeepMind and Isomorphic Labs launched AlphaFold 3 (AF3), a revolutionary AI system capable of predicting the 3D structures and interactions of proteins, nucleic acids, small molecules, ions, and other biomolecules with remarkable precision.

10 Oct 2025

UC Davis wins NSF grants to advance AI-driven protein engineering

Two projects at the University of California, Davis, that use artificial intelligence to design and engineer proteins for industrial and health applications have been funded by the U.S. National Science Foundation (NSF).

19 Sep 2025