Proteome News and Research

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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

New project explores mitochondrial evolution across diverse life forms

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

1 Oct 2026

Atlas Antibodies marks 20 years of Human Protein Atlas–validated antibodies

Atlas Antibodies is 20 years old. The company is the original manufacturer of the antibodies used to map the human proteome in the Human Protein Atlas (HPA).

From Atlas Antibodies AB 30 Sep 2026

Researchers find secret protein that drives cancer cell division

A previously unknown protein, hidden in RNA thought not to encode proteins, helps cells divide correctly. The RNA molecule that encodes the protein also has a function of its own in cell division.

25 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

Study reveals how red blood cells adapt to low oxygen

They account for nearly 83% of all cells in the human body, yet red blood cells are often portrayed as little more than bags of hemoglobin ferrying oxygen from the lungs to the heart and beyond.

18 Sep 2026

AI-designed drug candidate reverses biological age in clinical study

Insilico Medicine ("Insilico"), a clinical-stage company focused on generative AI-driven drug discovery and development, today announced the publication of a new study conducted in collaboration with an international team of scientists from Harvard Medical School, Stanford University, The Broad Institute, RWTH Aachen University, Peking University and Westlake University.

7 Sep 2026

Harvard scientists discover entirely new gene regulation system in mammals

For decades, scientists have understood that each of the roughly 20,000 genes in the human body carries the instructions for a single kind of protein.

2 Sep 2026

Review uncovers how tryptophan metabolism affects female reproductive health

In recent years, issues concerning female reproductive health have become a global challenge that cannot be ignored.

24 Aug 2026

Sprint exercise sends a very different molecular signal through the body

Sprint-interval exercise triggers a much larger and faster shift in circulating proteins and metabolites than moderate-intensity exercise, revealing distinct patterns of predicted communication between organs. The findings suggest that exercise intensity shapes systemic molecular signaling, with skeletal muscle and adipose tissue emerging as potential source and target tissues linked to cardiometabolic health.

16 Aug 2026

New review urges proteostatic fitness standards for stem cell therapies

Stem cell therapies have expanded rapidly, with more than 115 clinical trials involving over 1,200 patients approved by late 2024. The U.S. Food and Drug Administration (FDA) recently approved Ryoncil (remestemcel‑L) for children with steroid‑refractory acute graft‑versus‑host disease, signaling a major shift toward routine clinical use.

11 Aug 2026

Study uses alternative splicing data to predict protein function

A single human gene can produce multiple protein isoforms through alternative splicing, greatly expanding the functional diversity of the proteome.

10 Aug 2026

Study reveals sex-based protein differences across lung cancer types

Biological sex factors into cancer in ways you might not expect. In lung cancer, a form called squamous cell carcinoma disproportionately affects males while adenocarcinoma occurs more frequently in females.

21 Jul 2026

Smoking shows no major impact on the eye microbiome in small study

A small study found no evidence that smoking causes large or consistent shifts in the ocular surface microbiome or tear proteome. The authors caution that subtle smoking-related effects cannot be ruled out, given the small cohort and the ocular surface's low-biomass, contamination-sensitive microbial niche.

8 Jul 2026

Researchers uncover unexpected bacterial strategy for surviving antibiotic stress

Escherichia coli (E. coli) are mostly harmless bacteria that live in the intestines of animals and humans. They are the most well-studied bacteria and, often, when scientists discover something about E. coli, they extrapolate that discovery across all bacteria.

3 Jul 2026

Blood protein clocks flag higher risks of death and chronic disease

Proteomic age clocks applied to two European cohorts linked faster biological aging with smoking, alcohol use, physical inactivity, all-cause mortality, cardiovascular disease, dementia, and several cancers. The Global proteomic clock predicted mortality as well as established lifestyle risk factors, while organ-specific clocks showed stronger links with related cancers of the kidney, lung, and stomach.

30 Jun 2026

Biognosys showcases next-gen multiomics innovations at ASMS 2026

The Biognosys Group, a leader in mass spectrometry-based multiomics, announces advancements across its integrated multiomics portfolio, highlighting next-generation software, sample preparation, enrichment, and separation technologies for proteomics and metabolomics.

From Biognosys 26 Jun 2026

Pioneering technique maps the proteome of individual cardiomyocytes

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes-the cells responsible for heart contraction.

24 Jun 2026

Cytoskeletal proteins in the cell nucleus influence brain development

The cytoskeleton gives cells their shape and helps them move. Researchers at Helmholtz Munich and the Ludwig Maximilian University now show that, in neural stem cells, proteins of the cytoskeleton are also found in the cell nucleus, where they can influence developmental programs.

23 Jun 2026

New human protein atlas maps how cancer rewires the body’s tissues

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and tumor tissues. The resource maps tissue-specific protein patterns, cancer-associated changes, organ-specific drug-toxicity signals, and candidate therapeutic targets.

21 Jun 2026

Targeting immune cells could improve colorectal cancer treatments

Researchers at the Medical University of Vienna have described a mechanism in metastatic colorectal cancer that has received little attention to date: a key target of existing therapies, the so-called epidermal growth factor receptor (EGFR), is likely to affect more than just the cancer cells themselves.

17 Jun 2026