Quadriceps News and Research

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From caffeine to trigonelline, coffee has surprising links to muscle biology

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose uptake, and protein turnover. Human studies reported associations with greater muscle mass and lower frailty or functional impairment, but most evidence remains observational or preclinical and cannot establish causality.

25 Aug 2026

Repeatedly losing and gaining weight may accelerate muscle loss

Repeatedly losing and gaining weight may do more than frustrate dieters - it also accelerates muscle loss in middle-aged people, according to new UC San Francisco research that comes as weight-loss medications transform obesity treatment.

21 Jul 2026

Advancing Human Muscle Models for Drug Development and Preclinical Testing

Transforming drug development, Myomaker Bio's lab-grown muscle platforms offer human-relevant models for effective preclinical testing and risk reduction.

From Myomaker Bio 2 Jun 2026

$2 million NIH funding supports wearable knee exoskeleton research

Building on the success of projects to boost strength by adding motors to conventional knee, hip and ankle braces, a University of Michigan team is exploring how well this approach could work for relieving knee pain from osteoarthritis.

1 Jun 2026

Epidural stimulation and physical rehabilitation can enhance recovery in spinal cord injury patients

Spinal cord injury (SCI) causes paralysis in roughly one million people worldwide, with incident cases rising yearly.

21 Oct 2025

Wireless ultrasound shows promise for faster injury assessment in athletes

Many student-athletes are preparing or returning to the field or court for their upcoming season. With the start of both collegiate and professional sports, injuries are inevitable - and when they do happen, getting fast, reliable results can make all the difference.

4 Sep 2025

$New insights into diagnosis and treatment of tibial tubercle avulsion fractures in young athletes$

New insights into diagnosis and treatment of tibial tubercle avulsion fractures in young athletes

As youth engagement in high-energy sports surges, so does the prevalence of sport-related injuries. Among them, tibial tubercle avulsion fractures (TTAFs) represent a small but serious subset, accounting for less than 3% of pediatric fractures.

18 Jul 2025

Study shows connection between ultra-processed foods and intramuscular fat

A diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of the amount of calories consumed or level of physical activity, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2024

Olympic athletes overcome health challenges to reach the pinnacle of their sport

The athletes have done the training and achieved their dreams, a trip to the Paris Olympics set to begin Friday July 26th.

2 Aug 2024

New study reveals sweet spot for muscle growth

When performing resistance training such as lifting weights, there's a lot of interest in how close you push yourself to failure – the point where you can't do another rep – and how it affects your results.

1 Aug 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

Study proposes novel approach to slow neuromuscular degeneration in ALS patients

A study led by the Center for Biomaterials and Tissue Engineering of the Universitat Politècnica de València, member of Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine, in collaboration with the Instituto de Investigación Sanitaria La Fe and the University of Zaragoza proposes a novel approach to slow neuromuscular degeneration in patients with Amyotrophic Lateral Sclerosis.

20 Feb 2024

Stronger quadriceps may reduce knee replacement risk

Stronger quadriceps muscles, relative to the hamstrings, may lower the risk of total knee replacement, according to research being presented today at the annual meeting of the Radiological Society of North America.

27 Nov 2023

The effect of vegetarian diets on sports performance

The effects of vegetarian and omnivorous diets on athletic performance.

8 Nov 2023

IV plus PA corticosteroids may improve key indicators of functional recovery after total knee arthroplasty

For patients undergoing total knee arthroplasty (TKA), a combination of intravenous and periarticular corticosteroids does not improve pain control – but, may improve key indicators of functional recovery in the days after surgery, reports a trial in The Journal of Bone & Joint Surgery.

25 May 2023

Heart attack patients with strong legs less likely to develop heart failure

People with strong legs are less likely to develop heart failure after a heart attack, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

Nitrate boost causes an increase in muscle force during exercise

A new study has found that consuming dietary nitrate – the active molecule in beetroot juice – significantly increased muscle force while exercising.

23 Jan 2023

Knee extension velocity while seated strongly predicts walking performance

"Speed or strength, which is more important?" may be a critical question for not only athletes but also knee surgery patients.

13 Jan 2023

Partial knee arthroplasty yields faster functional recovery than total knee replacement

For selected patients with knee osteoarthritis, unicompartmental (or "partial") knee arthroplasty (UKA) shortens the recovery time for two key measures of physical function, as compared with total knee arthroplasty (TKA), reports a randomized trial in The Journal of Bone & Joint Surgery.

22 Dec 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022