Renal Replacement Therapy News and Research

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Survey reveals gaps in acute kidney injury prevention across intensive care

Acute kidney injury (AKI) remains one of the most frequent and clinically significant complications among critically ill patients, affecting nearly half of those admitted to intensive care units (ICUs).

3 Jul 2026

Study finds different types of crystalloid fluids are equally effective for pediatric sepsis

A major study, led by researchers at Children's Hospital of Philadelphia, Nemours Children's Health, and Children's National Hospital and involving an extensive network of medical centers across the United States and abroad, found that different types of crystalloid fluid resuscitation were equally effective for staving off the most serious adverse kidney events after the treatment of pediatric patients with suspected septic shock.

25 Apr 2026

Targeted PICU rounds reduce the rate of healthcare-associated conditions

Rounds focused on critically ill pediatric patients at the greatest risk for developing healthcare-associated conditions (HACs) reduced the rate of specific HACs by nearly 50% at a Colorado hospital, according to a study published in Critical Care Nurse (CCN).

3 Feb 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Vaccination linked to better kidney outcomes in hospitalized COVID-19 patients

Vaccinated patients hospitalized with COVID-19 who developed acute kidney injury had better outcomes than unvaccinated patients with the same condition, new research suggests.

14 Jun 2025

Statins linked to lower death rates in critically ill sepsis patients

Sepsis is when the immune system overshoots its inflammatory reaction to an infection, so strongly that the vital organs begin to shut down.

6 Jun 2025

Pentoxifylline offers no survival benefit for severe alcohol-associated hepatitis

Severe alcohol-associated hepatitis (sAH) remains a highly lethal condition with limited therapeutic options. Characterized by rapid liver decompensation, sAH is often accompanied by acute kidney injury (AKI), a complication that substantially worsens prognosis.

13 May 2025

Intravenous infusion of exenatide fails to reduce risks of complications in heart surgery patients

A large-scale clinical trial found that intravenous infusion of exenatide, a glucagon-like peptide-1 (GLP-1) analog medication, during heart surgeries involving bypass did not significantly reduce the risk of death, stroke or organ failure.

18 Nov 2024

Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy

A UCLA-led team has developed a machine-learning model that can predict with a high degree of accuracy the short-term survival of dialysis patients on Continuous Renal Replacement Therapy (CRRT).

11 Jul 2024

Impella CP pump shows survival benefit in cardiogenic shock

Implantation of the Impella CP micro-axial flow pump in the hours after a heart attack significantly increased the rate of survival at six months among people suffering cardiogenic shock, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Balanced IV fluids can reduce death risk for critically ill patients

Results of a new meta-analysis in shows that intravenous fluid (IV) therapy using balanced solutions rather than commonly used saline can reduce the risk of in-hospital death of critically ill patients by four percent.

30 Nov 2023

ECLS does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock

Early extracorporeal life support (ECLS) does not improve survival in patients with acute myocardial infarction complicated by cardiogenic shock who are scheduled for early revascularization, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

Comparing clinical characteristics and outcomes of critically ill COVID-19 patients with a chohort admitted to ICU for influenza pneumonia

A recent study evaluated clinical differences between critically ill COVID-19 and influenza patients.

19 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Japanese study reveals increase in incidence rates of renal replacement therapy attributed to nephrosclerosis

A new Japanese study reveals that the age-standardized incidence rates of end-stage kidney disease (ESKD) requiring renal replacement therapy (RRT) due to chronic glomerulonephritis and diabetic nephropathy has decreased, while rates due to nephrosclerosis have increased considerably between 2006 and 2020.

23 Dec 2022

Prevalence and severity of liver enzyme alterations in COVID-19 and association with patient-centered outcomes

Researchers examined the prevalence of changes in liver enzymes in COVID-19.

15 Nov 2022

Acute kidney injury in hospitalized COVID-19 patients

In a new study, researchers examined the phenotypes of acute kidney injury (AKI) in hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Oct 2022

International medical experts aim to use biomarker-based approaches to advance precision medicine

The diagnostics company SphingoTec GmbH (SphingoTec), announces that, during the 4th Scientific Symposium held near Potsdam, Germany, international medical experts discussed the latest developments in diagnostic and therapeutic innovations for advancing precision medicine in critically ill patients.

11 Aug 2022