Rheumatism News and Research

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Rheumatism is a group of disorders marked by inflammation or pain in the connective tissue structures of the body. These structures include bone, cartilage, and fat.

Researchers uncover immune loop driving Sjögren's disease progression

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

10 Jun 2026

Patient organizations strengthen support for people with rheumatic diseases

Rheumatic and musculoskeletal diseases (RMD) are chronic, often lifelong conditions. EULAR - The European Alliance of Associations for Rheumatology - works with the network of national organizations of People with Arthritis/Rheumatism in Europe (PARE) to ensure the voices of people with RMD are heard and have influence among decision makers - creating powerful alliances that make a real difference to lives.

7 Jun 2026

Natural peptide PEPITEM shows promise in reducing arthritic joint swelling

Scientists investigating the naturally occurring immunopeptide PEPITEM have shown reductions in arthritic joint swelling to a degree comparable to the current standard of care, and reduce the inflammatory changes that cause joint damage.

13 Apr 2026

High-intensity interval training improves fitness in people with inflammatory muscle disease

High-intensity interval training boosts fitness and muscle endurance more effectively than traditional home exercise programmes in people recently diagnosed with inflammatory muscle disease.

28 Nov 2025

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.

22 Oct 2025

Deadly brain cancer erodes skull bone and alters immune marrow

Scientists at Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine have shown for the first time that glioblastoma-the deadliest form of brain cancer-affects not just the brain but also erodes the skull, alters the makeup of skull marrow, and interferes with the body's immune response.

3 Oct 2025

IL-17A identified as a potential driver of cancer in familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer.

25 Apr 2025

Anti-HIV active diterpenoids identified in Daphne pseudomezereum

A research group led by Professor Wei Li from the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with the Duke University Medical Center in the United States, has discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).

21 Mar 2025

Scientists reveal how Epstein-Barr virus reactivation triggers MIS-C in children

Scientists reveal that reactivation of Epstein-Barr virus (EBV), driven by TGFβ-induced immune suppression, is a key driver of multisystem inflammatory syndrome in children (MIS-C) following COVID-19. Blocking TGFβ may offer a potential new treatment for this life-threatening condition.

13 Mar 2025

Ultra-processed foods increase active psoriasis risk, study shows

This study highlights a significant link between high ultra-processed food (UPF) consumption and active psoriasis, independent of BMI and other factors. The findings emphasize UPFs' contribution to proinflammatory pathways in individuals with this chronic skin condition.

1 Dec 2024

Breakthrough method sheds light on how immune receptors detect infections

Researchers from the University of Bonn are using an innovative method to watch immune receptors go about their business.

12 Nov 2024

New biomarker could predict response to IBD treatment

Not everyone responds equally well to treatments for inflammatory bowel disease (IBD). What will work for individual patients involves trial and error during the treatment process.

7 Nov 2024

Individuals with periodontitis exhibit unique inflammatory protein profile in the blood

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden.

6 Sep 2024

Therapeutic properties and and phytochemical profile of greater galangal

Announcing a new article publication for BIO Integration journal. Various secondary metabolite compounds from plants have been found in recent decades, one of which is Alpinia galanga L. (greater galangal).

25 Jul 2024

Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis

Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.

13 Jun 2024