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New bacterial control strategy helps revive failing last-line antibiotics

Antimicrobial resistance is one of the world's most alarming public health challenges, because the multidrug-resistant (MDR) gram-negative bacteria increasingly render even last-line antibiotics ineffective, leading to substantially higher mortality rates.

23 Jul 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026

How a common gut bacterium may protect health

Akkermansia muciniphila's impact on immunity and pregnancy outcomes underscores its promise as a probiotic, with implications for infectious disease treatment.

4 May 2026

Gut microbial butyrate enhances mucosal vaccine antibody responses

A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new mechanism showing how butyrate-a short-chain fatty acid produced by gut commensal bacteria-enhances T follicular helper (Tfh) cell activity to promote antibody production and strengthen mucosal vaccine efficacy.

4 Feb 2026

Marine bacterium shows powerful therapeutic effects against colorectal cancer

A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.

21 Nov 2025

Portable SERS test detects harmful bacteria in beef within minutes

A breakthrough method combines silver nanoparticles and Raman spectroscopy for quick detection of foodborne pathogens in beef, improving safety standards.

10 Oct 2025

Engineered Salmonella therapy delivers immune payloads to combat cancer

A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled "ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response."

8 Oct 2025

Uganda’s most vulnerable region faces high Salmonella burden

In the dry, isolated area of Karamoja in northeastern Uganda – the country’s poorest sub-region – children have long suffered from malnutrition and water shortages.

26 Sep 2025

Mucins show promise in preventing Salmonella infections

Mucus is more than just a sticky substance: It contains a wealth of powerful molecules called mucins that help to tame microbes and prevent infection.

25 Sep 2025

Bacteria and viruses team up to target cancer

Researchers at Columbia Engineering have built a cancer therapy that makes bacteria and viruses work as a team.

18 Aug 2025

Gut bacteria send direct signals to the brain to stop you from overeating

Researchers have discovered a novel gut-brain sensory circuit in mice where specialized colonic cells sense bacterial flagellin and rapidly suppress feeding via the vagus nerve. This "neurobiotic sense" operates independently of immune pathways, revealing a direct neural mechanism for microbiota-host communication.

24 Jul 2025

Hungry bacteria choose food over danger in the human gut

Bacteria that cause intestinal infections typically avoid a stinky chemical - one that can kill them at high enough concentrations - inside human intestines, but they may actually swim toward it when a hearty meal is the reward.

16 Jul 2025

Magnolia essential oil fights bacteria and oxidative stress with natural potency

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17 Apr 2025

Why Mānuka isn't the only healing honey from New Zealand anymore

New research from Auckland University of Technology reveals that eight native New Zealand honeys, beyond mānuka, possess unique antioxidant, antibacterial, and bioactive properties. Thyme and beech honeydew stood out for their vitamin C and polyphenol content.

25 Mar 2025