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Scientists find a universal gut microbiome pattern linked to colorectal cancer

Researchers analyzed 6,779 stool microbiome profiles and 906 tissue samples to identify a colorectal cancer microbial signature that remained consistent across age groups, populations, and sequencing methods. The signature aligned with tumor-resident microbes, showed weaker detection for adenomas, and was inversely associated with dietary fiber intake.

25 Jun 2026

Plague emerged earlier than thought and hit hunter-gatherers hard

Ancient DNA from 46 Lake Baikal hunter-gatherers revealed two early plague outbreak phases about 5,500 years ago, with Yersinia pestis detected in 18 individuals. The findings suggest these basal plague strains caused lethal, child-heavy outbreaks long before dense farming societies, cities, or classical flea-borne bubonic plague emerged.

21 Jun 2026

Gut bacteria may help explain why fatigue appears before illness

A small study of healthy Japanese adults found that fatigue was associated with distinct gut microbiome, microbial gene, and fecal metabolite patterns. The findings suggest fatigue may track with altered microbial energy metabolism and oxidative stress-related functional potential, but larger longitudinal studies are needed to test causality and clinical value.

16 Jun 2026

New Japanese database reveals how gut microbes and diet connect

Researchers have launched the NIBN Japan Microbiome Database, featuring over 2,000 gut microbiome profiles from healthy Japanese adults with extensive lifestyle and dietary metadata. This resource aims to accelerate microbiome-health research and enable precision medicine insights.

5 Jun 2025

Can microbiome discoveries finally become treatments? Scientists show the way

Researchers propose a novel iterative strategy combining big data and experimental models to move microbiome research from theory to clinical applications. The study highlights the need to bridge the gap between correlation and causation to develop effective microbiome-based therapies.

9 Mar 2025

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

Atlantia Clinical Trials investigates the role of microbiomes in immunity, focusing on gut and lung interactions to develop innovative health solutions.

From Atlantia Clinical Trials 28 Feb 2025

Scientists track diet through stool DNA, revealing a new way to monitor nutrition

Scientists developed MEDI, a method to estimate dietary intake from food DNA in human stool, offering a more accurate alternative to self-reported food tracking.

19 Feb 2025

How gut bacteria regulate stress and sleep cycles

This study reveals that gut microbiota, particularly Lactobacillus species, regulate the daily rhythm of stress hormones like corticosterone, influencing stress responses and brain function at different times of the day. Disruptions in gut bacteria lead to altered stress responses and increased susceptibility to disorders like depression.

10 Nov 2024

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Researchers examine the relationship between gut microbiota and multiple sclerosis.

21 Aug 2024

Cytomegalovirus in breast milk linked to changes in infant growth and gut microbiome

Research shows human cytomegalovirus (CMV) reactivation in breast milk affects milk composition, infant gut microbiome, and growth, with potential impacts on neonatal health.

28 Jul 2024

New study links psoriasis severity to skin microbiome dysbiosis

A multi-omics analysis of host-microbe interactions in psoriasis.

28 Jun 2024

Tailored diet could boost growth in malnourished kids via gut bacteria action

Study demonstrates how microbiota-targeted food (MDCF-2) and the presence of Prevotella copri in the gut can enhance weight gain in malnourished children, offering a novel approach to treating malnutrition through diet and microbiome manipulation.

20 Mar 2024

Tracing Monkeypox virus: Leveraging ancient orangutan DNA to investigate the 1965 Rotterdam Zoo outbreak

Ancient DNA analysis of museum-preserved orangutan teeth reveals the cause of the 1965 zoo outbreak in the Netherlands as monkeypox virus (MPXV) infections, demonstrating the power of museomic techniques in tracing historic viral transmissions.

12 Mar 2024

Microbial signatures linked to immunotherapy response across cancers

The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma.

1 Mar 2024

Ancient Brazilian genomes may hold the secrets of treponemal evolutionary history

Study reconstructs four ancient treponeme genomes from 2,000-year-old Brazilian remains, revealing their close relation to the bejel-causing Treponema pallidum endemicum and challenging previous hypotheses about treponeme subspecies adaptability.

25 Jan 2024

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

New reference database Greengenes2 improves reproducibility of microbiome studies

Two leading sequencing techniques are no longer at odds, thanks to an international effort led by scientists at University of California San Diego.

27 Jul 2023

A novel approach to quantify personal information contained within gut metagenome data

Researchers used shotgun sequencing to extract human reads from DNA in fecal samples

17 May 2023

Study describes a novel, non-destructive method to extract DNA from ancient bone and tooth artifacts

Researchers described a new method to safely release DNA from ancient tooth and bone artifacts.

5 May 2023

RExMap unlocks gut microbiome secrets: Revealing their global influence on health

Groundbreaking RExMap database enables species-level mapping of gut microbes, revealing a core set of fifteen microbes shared by humans across the globe.

21 Apr 2023