Stenosis News and Research

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A stenosis is an abnormal narrowing in a blood vessel or other tubular organ or structure.

Elusive stem cells offer clues to treat lumbar spinal stenosis

Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the stem cells—unspecialized cells that can develop into specific cell types—that give rise to the body's tendons and ligaments, the tissues connecting muscles and bones.

7 Sep 2026

Anticoagulation lowers subclinical leaflet thrombosis after TAVI procedure

After transcatheter aortic valve implantation (TAVI), anticoagulation reduced imaging signs of clot formation on the new valve compared with antiplatelet therapy, without compromising safety. This was the main finding of the ACASA-TAVI trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in JAMA.

31 Aug 2026

TAVI-first strategy proves noninferior to PCI-first approach in new trial

A TAVI-first strategy was noninferior to a PCI-first strategy after one years' follow-up, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

30 Aug 2026

Functional angiography outperforms conventional imaging in AIR-STEMI trial

Functional coronary angiography significantly reduced cardiovascular events and improved safety compared with conventional angiography in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease.

29 Aug 2026

Researchers identify risk factors for postoperative cerebral ischemia in patients with moyamoya disease

The buildup of fats, cholesterol, calcium, and immune cells within the blood vessel can lead to the narrowing or even complete blockage of the blood vessel.

20 Jul 2026

Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome

Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes in metabolic syndrome (MetS).

14 Jul 2026

Gum disease bacteria linked to calcific aortic valve stenosis

Gum disease bacteria may spur calcium buildup in the heart's aortic valve, leading to a common and serious heart valve disease, according to preliminary, independent research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2026.

12 Jul 2026

Landmark study confirms long-term durability of Ross procedure for aortic valve replacement

The Ross procedure, a highly specialized option for aortic valve replacement, is associated with significant long-term durability and excellent outcomes in a wide range of adult patients with aortic valve disease.

23 Jun 2026

Engineered cartilage grafts improve surgery for narrowed child airways

A study led by researchers at Children's Hospital of Philadelphia (CHOP) demonstrated a new method of using decellularized cartilage with patient-specific cells to help enlarge the pediatric airways narrowed as a result of severe subglottic stenosis.

17 Jun 2026

Moderate air pollution associated with advanced coronary artery disease

In one of the largest studies to date, researchers examined the relationship between long-term air pollution exposure and coronary atherosclerosis and found that even at moderate levels, long-term exposure to air pollution is associated with more advanced coronary artery disease.

9 Jun 2026

Large genetic study discovers new risk factors for spinal stenosis

An international research team has identified dozens of new genetic risk factors linked to lumbar spinal stenosis, a common degenerative condition of the lower spine.

9 Jun 2026

Role of coronary revascularization in TAVI patients with severe aortic stenosis and CAD

The EuroPCR Course Directors have selected 3 major late-breaking trials that will be presented for the first time during EuroPCR 2026 and are set to impact practice worldwide.

20 May 2026

Endometriosis increases risk of some birth defects in infants

Research indicates women with endometriosis may face a higher risk of congenital anomalies in infants, emphasizing the need for further investigation.

13 May 2026

Brain artery widening may drive lacunar stroke more than artery narrowing

Abnormal brain artery widening is associated with lacunar stroke, indicating a shift in understanding the mechanisms behind small vessel disease in the brain.

11 May 2026

Email alerts boost valve replacement rates in older patients with aortic stenosis

New data finds older patients with severe aortic stenosis (AS) were more likely to receive aortic valve replacement (AVR) and survive when clinicians received automated email notifications with abnormal heart ultrasound results detecting AS.

25 Apr 2026

Novel algorithm improves detection of moderate-to-severe aortic stenosis

A novel detection algorithm spotted moderate-to-severe aortic stenosis (AS) with a sensitivity of 90.5% of all patients and 100% of African American patients.

24 Apr 2026

Tirzepatide significantly reduces cardiovascular risk in high-risk patients

Two new studies show that tirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist (RA), significantly reduces cardiovascular risk in high-risk patients, including those undergoing percutaneous coronary intervention (PCI) and those with obesity undergoing transcatheter aortic valve replacement (TAVR).

23 Apr 2026

Loneliness is linked to higher risk of degenerative heart valve disease

Adults who reported feeling lonely had a higher risk of developing degenerative heart valve disease, even after accounting for traditional heart disease risk factors and genetics, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.

15 Apr 2026

Study proposes genetic basis for autism’s strong sex bias

Autism has a significant and enduring sex bias, with roughly four boys diagnosed for every girl. For many years, experts have believed this disparity arises primarily from diagnostic inequities because much of autism research - and the screening tools that grew out of it - has historically focused on boys, effectively setting a male standard for what autism "looks like."

30 Mar 2026

Robot-assisted system found to be feasible for diagnostic cerebral angiography

Digital subtraction angiography remains the gold standard for diagnosing cerebrovascular diseases, including intracranial aneurysms, arteriovenous malformations, and arterial stenosis.

13 Mar 2026