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Review examines translational bottlenecks for plant-derived anti-inflammatory compounds

A review led by Professor Weidong Zhang at the School of Pharmacy, Naval Medical University, was published in Volume 2 of the journal Immunity & Inflammation on October 27, 2026. The article systematically examines the translational bottlenecks and potential solutions for plant-derived anti-inflammatory compounds.

5 Nov 2026

Sponge and sea slug partnership yields a new anticancer molecule with drug design promise

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

8 Apr 2026

Analyzing bacterial enzymes in pikromycin synthesis

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin infections.

21 Jan 2026

Unlocking the power of stereochemistry to improve mRNA drug delivery

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs.

1 Aug 2025

Sapio Sciences introduces new tools for chemistry, molecular biology, GMP workflows, and immunogenicity

Sapio Sciences, the science-aware™ lab informatics platform, today announced the launch of Release 24.12, introducing new tools for chemistry, molecular biology, GMP workflows, and immunogenicity.

15 Jan 2025

Sapio Sciences Announces Enhanced Capabilities for Chemistry, Immunogenicity, GMP and Molecular Biology

Sapio Sciences' Release 24.12 enhances lab informatics with improved GMP workflows and molecular biology features, driving efficiency and scientific discovery.

From Sapio Sciences 14 Jan 2025

Breakthrough in synthesizing complex plant molecules

MIT chemists have developed a new way to synthesize complex molecules that were originally isolated from plants and could hold potential as antibiotics, analgesics, or cancer drugs.

14 Aug 2024

Inaoside A: Novel antioxidant compound found in Laetiporus cremeiporus mushrooms

Natural products have unique chemical structures and biological activities and can play a pivotal role in advancing pharmaceutical science.

11 Mar 2024

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Researchers explore the anti-acne, antioxidant, and anti-inflammatory properties of Stingless bee (Tetragonula biroi)-derived propolis.

29 Nov 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

FSU chemists develop a faster way to synthesize compounds for drug development

A team of Florida State University chemists has developed a faster way to synthesize a class of compounds that are commonly used in the development of new medications.

12 Oct 2021

New thermoplastic biomaterial could lead to cost-effective, versatile medical implants

A new thermoplastic biomaterial, which is tough and strong but also easy to process and shape has been developed by researchers at the University of Birmingham.

1 Jul 2020

New method determines the atomic structure of natural products more rapidly, accurately

Many drugs are derived from natural products. But before natural products can be exploited, chemists must first determine their structure and stereochemistry.

21 Jan 2020

Research provides drug developers with much needed insight into serotonin receptor

Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface of cells. Far from it. Many approved drugs also bind to serotonin receptors.

21 Aug 2018

Scientists create new tool to precisely control 3D architecture of linkages in drugs

When it comes to certain molecules, shape makes all the difference. The shape of limonene, for instance, a compound produced by citrus fruits, determines whether it tastes like orange juice or turpentine.

7 Aug 2018

Scientists synthesize new compound with anticarcinogenic properties

The patent has been registered from the University of Seville and licensed by the British company Evgen Pharma, which is currently developing programmes aimed at breast cancer, subarachnoid haemorrhage and multiple sclerosis, among others

5 Jul 2018

Iron-containing catalysts can alter amino acids to help develop new drug candidates

For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids -- the building blocks of peptides and proteins -- into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness."

2 Aug 2016

Tianyin Pharmaceutical releases unaudited preliminary financial results for Q1 FY 2015

Tianyin Pharmaceutical Inc., a pharmaceutical company that specializes in the patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), branded generics and active pharmaceutical ingredients (API) released unaudited preliminary financial results for the first quarter of fiscal year 2015.

25 Dec 2014

Enterococcal cytolysin synthetase helps form distinctly different, 3-D protein ring structures

While working out the structure of a cell-killing protein produced by some strains of the bacterium Enterococcus faecalis, researchers stumbled on a bit of unusual biochemistry. They found that a single enzyme helps form distinctly different, three-dimensional ring structures in the protein, one of which had never been observed before.

23 Jan 2013