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New study uncovers bacterial route to testosterone production

Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects.

4 Sep 2026

Hidden sperm structures may offer new clues to male fertility

Researchers at VIB, VUB, and the Medical Research Council Laboratory of Molecular Biology (UK) have discovered a hidden feature of human sperm cells.

2 Sep 2026

Targeting cyclin-dependent kinases offers new pathways for cancer therapy

Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that target the uncontrolled growth of tumor cells, a class of enzymes known as cyclin-dependent kinases (CDKs) has come into focus.

24 Aug 2026

Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms

All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the molecules responsible for helping build proteins that keep organisms alive.

20 Aug 2026

Weizmann study reveals how DNA repair enzymes choose targets

When a wound does not heal properly, it leaves a scar. Similarly, mutations – which are permanent changes to genetic code – are often the result of damaged DNA that has not been properly repaired.

14 Aug 2026

New antibody-specific AI framework accelerates discovery of therapeutic drugs

Designing an effective antibody drug is like searching for the right key in a warehouse of locks. Scientists may begin with millions-or even billions-of antibody candidates, but only a tiny fraction will recognize and bind tightly to the disease target.

13 Aug 2026

Liver’s internal clock coordinates daily metabolic communication, study finds

What if one of the keys to a healthier metabolism is understanding how and when the liver communicates with the rest of the body?

12 Aug 2026

Researchers discover smart molecular glue that activates inside oxidative cancer cells

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

7 Aug 2026

Chemists use programmable DNA to build precise protein crystals

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.

29 Jul 2026

Rare BTK mutation drives resistance to targeted therapies for blood cancer

Scientists at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, and collaborators have uncovered a rare genetic mutation that enables some blood cancers to evade both approved Bruton tyrosine kinase (BTK) inhibitors and newer BTK degraders, a finding that could help shape the next generation of therapies for patients with chronic lymphocytic leukemia (CLL) and related malignancies.

27 Jul 2026

Structural study identifies unexpected cancer-regulating functions of MLL4 protein

The epigenetic modifier MLL4 has an unassuming name-the 4, for instance, indicates it's just one in a family of such modifiers.

13 Jul 2026

Researchers uncover hidden mechanism behind cancer-linked SPOP mutations

Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the presence and absence of these mutations.

13 Jul 2026

New viral library helps scientists study thousands of proteins

To prevent viruses from sickening or killing us - whether it's an individual case of hepatitis B or a COVID pandemic - it's crucial to understand how the proteins they make initiate changes in our bodies that allow them to flourish.

11 Jul 2026

Discovery provides key insights into cellular mechanisms underlying female fertility

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these follicles, the oocyte is surrounded by granulosa cells that supply nutrients, signaling molecules, and structural support essential for egg development.

2 Jul 2026

UC San Diego study reveals genetic causes of rare neuromuscular disorders

Scientists at the University of California San Diego have uncovered how genetic mutations cause a rare group of inherited neuromuscular disorders and identified promising new strategies to correct them, including a potential new use for an existing antidepressant.

1 Jul 2026

Researchers map structural changes of viruses during the dehydration process

Abhishek Mall from the Max Planck Institute for the Structure and Dynamics of Matter in Hamburg (MPSD) and his colleagues explored the structural dynamics of the protein shells - called capsids - that enclose the genetic material of viruses.

30 Jun 2026

Scientists unlock molecular structure of key protein linked to cancer, neurological diseases

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases.

23 Jun 2026

Purdue develops next-generation platform to accelerate cancer drug discovery

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to dramatically accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies.

16 Jun 2026

Laser phase plate dramatically expands cryo-EM imaging capabilities

In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today announced the successful demonstration of the laser phase plate, a novel device that dramatically improves the contrast of images produced by cryo-electron microscopes, opening up an entirely new view of human biology.

11 Jun 2026

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Professor Heddle's insights on nanobiology and AI highlight their potential to innovate drug delivery and vaccine development, addressing critical health needs.

9 Jun 2026