Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

TIBI researcher receives NIH grant for 3D-bioprinted retinal grafts

We are pleased to announce that Dr. Johnson V. John, Assistant Professor at the Terasaki Institute for Biomedical Innovation (TIBI), has received an R56 grant from the National Eye Institute (NEI) of the National Institutes of Health (NIH).

30 Oct 2026

New iron contrast agent offers safer cardiac MRI scans

The Biomolecular Nanotechnology research group led by Ikerbasque research professor Aitziber L. Cortajarena from CIC biomaGUNE has developed a new iron-based contrast agent for magnetic resonance imaging that can be used for both diagnosis and treatment.

29 Oct 2026

Understanding how neutrophil signaling pathways disrupt the human intestinal barrier

The intestinal mucosal barrier separates the host from the gut lumen and is essential for systemic homeostasis.

14 Oct 2026

Novel bioprinting technique successfully replicates mature human fat tissue

A research team has developed a support-bath bioprinting method that enables fragile, mature human adipocytes to be incorporated into geometrically defined three-dimensional (3D) constructs while retaining their viability, characteristic lipid-filled morphology, and metabolic activity.

14 Oct 2026

Topical peptide spray outperforms placebo in healing burn wounds

Burn wound infections remain a major global health burden, often requiring hospitalization and delaying tissue repair.

13 Oct 2026

Targeting the RUNX1 gene helps reduce severe skin fibrosis

Skin fibrosis includes hypertrophic scar (HTS), keloid scar (KS), and systemic sclerosis (SSc). These conditions share persistent fibroblast activation, excessive extracellular matrix (ECM) deposition, and progressive skin remodeling.

13 Oct 2026

New framework aims to improve reliability of tear-based health sensors

Dr. Yangzhi Zhu of the Terasaki Institute for Biomedical Innovation (TIBI), with collaborators at UC San Diego and USC, published a Nature Sensors perspective on what it will take to turn tear-based wearable sensors into reliable, long-term health-tracking tools.

8 Oct 2026

A New Approach to Preventing Bladder Cancer Recurrence

Innovative techniques using electrical energy to treat bladder cancer may lower recurrence rates and minimize the need for radical surgical interventions.

8 Oct 2026

Nerve-stimulation device enters human trials for cancer-related cachexia

The Terasaki Institute for Biomedical Innovation announced today that OnVagus, a medical device company incubating at the Institute, has received institutional and regulatory approval to begin the first human trial of its noninvasive nerve-stimulation device for patients experiencing cancer-related wasting.

7 Oct 2026

Smart contact lens measures stress levels by analyzing human tears

A research team led by Dr. Yangzhi Zhu, Principal Investigator and Assistant Professor at the Terasaki Institute for Biomedical Innovation (TIBI), has developed a soft, reusable smart contact lens as part of its broader Ocular Library for the Analysis of Tear Biomarkers (OCULAB), a tear bioelectronics platform for noninvasive, longitudinal biochemical monitoring through the ocular surface and tear film.

24 Sep 2026

Marine carbohydrates offer valuable new resources for drug development

The ocean contains diverse carbohydrates that could serve as valuable resources for drug development. Algae, marine animals and microorganisms produce polysaccharides and related molecules with structures that are uncommon on land, including distinctive sulfate patterns, sugar linkages and branched architectures.

22 Sep 2026

Researchers develop biodegradable microneedle particles to enhance drug delivery

Researchers have developed biodegradable particles with microscopic needles that painlessly puncture the skin to help it absorb drugs delivered through patches or creams.

9 Sep 2026

Cellular glue protein found to help clear away dead cells

A protein which sticks cells and tissues together has been found to have a surprising second job: helping cells which are packed into a continuous sealed layer, also known as epithelial cells, engulf nearby dead cells.

27 Aug 2026

Scientists create brain organoids with distinct cortical regional identity

The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it's organized.

20 Aug 2026

Multi-organ chip uncovers key mechanisms behind cancer metastasis

Cancer spreading beyond the primary tumor – a process known as metastasis – is responsible for at least two-thirds of cancer deaths.

19 Aug 2026

Newly discovered protein pathway limits spinal cord injury damage

Spinal cord injury begins with immediate mechanical damage, but much of the lasting neurological loss develops during the secondary phase, when inflammation, oxidative stress and disrupted metabolism continue to injure surviving tissue.

10 Aug 2026

Researchers develop new strategy for controlling therapeutic peptide release from gelatin particles

Rice University engineers have developed a new strategy for controlling how therapeutic peptides are released from gelatin-based materials, a step that could make the small but powerful molecules more useful in tissue engineering and drug delivery.

7 Aug 2026

New mechanism linked to septic heart injury protection uncovered

Sepsis triggers widespread inflammation, circulatory failure and metabolic stress, and cardiac dysfunction is a common complication associated with sharply poorer outcomes.

31 Jul 2026

New stem cell vesicles accelerate diabetic wound healing

Diabetic foot ulcers are among the most serious complications of diabetes because prolonged inflammation, poor circulation, and defective angiogenesis can leave wounds open for months and increase the risk of infection and amputation.

31 Jul 2026