Tsai News and Research

RSS

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

A protective brain enzyme may counteract aging-associated cognitive decline

Cinzia Vicidomini, PhD, and Amar Sahay, PhD, of the Mass General Brigham Department of Psychiatry, the Harvard Stem Cell Institute and the Broad Institute of Harvard and MIT, are the lead and senior authors of a paper published in Nature Neuroscience, "An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilience."

15 Oct 2026

Beyond ‘bad’ cholesterol: new clues to the risk of heart disease

Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level.

13 Oct 2026

U.S. hospital closures outpace openings in rural and urban communities

More hospitals across the U.S. are closing than opening, and urban hospitals are closing at the same rate as rural ones, according to a new study led by Harvard T.H. Chan School of Public Health.

8 Oct 2026

Millions of Americans live in counties without a general surgeon

More than 15 million Americans live in one of the 1,180 US counties with no general surgeon, and 951 counties have no surgeon in any of 12 surgical specialties, according to a new national analysis announced today at the ACS Clinical Congress 2026 in Washington, D.C., and simultaneously published today in the Journal of the American College of Surgeons (JACS).

28 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Advanced AI cell models redefine modern cell biology research

Researchers at Stanford Medicine have developed two new artificial intelligence models of the biological cell.

15 Sep 2026

New tool amplifies and visualizes tiny protein changes

Imagine a brain teaser where the challenge is to spot the difference between two nearly identical sandcastles.

1 Sep 2026

Gene removal makes engineered immune cells more effective against osteosarcoma

Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma.

25 Aug 2026

Scientists create brain organoids with distinct cortical regional identity

The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it's organized.

20 Aug 2026

Brain scans reveal language-specific network of neurons even during nonlinguistic tasks

The language network in your brain can be seen, even if you aren't saying a word.

13 Aug 2026

Spatial transcriptomics study elucidates cellular dynamics during heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

10 Aug 2026

Researchers map how blood cells cross into the brain during aging

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Linguistic style in children predicts future mental health problems

Linguistic models that analyzed the words children used when talking about stressful events proved better at predicting future mental health problems than a panel of human experts.

31 Jul 2026

Researchers identify immune cell receptor that drives organ aging process

We may age at different rates, but none of us escapes aging. A study in mice and in human cells by Stanford Medicine researchers pins much of the blame on a particular type of immune cell's increased inability, with advancing age, to gobble up another immune cell type.

16 Jul 2026

Machine learning boosts medicine access in resource-limited healthcare settings

Managing a medical supply chain in low- and middle-income countries can mean navigating a landscape prone to extreme and unexpected disruptions.

2 Jul 2026

Using the mathematics of quantum mechanics to improve neuroblastoma outcomes

For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple.

22 Jun 2026

Blood-based indicator assesses organ age to predict disease risk

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

15 Jun 2026

AI-created miniproteins show promise for targeting hard-to-treat diseases

G protein-coupled receptors, or GPCRs, sit in the plasma membrane, the boundary that defines the inside and outside of a living cell. They communicate with nearly every physiological process in our bodies - from the ability to see and smell, to sensing of adrenaline, insulin, nutrients and medicines.

21 May 2026

MIDAS platform accelerates protein engineering through rapid PCR-based screening

Proteins are critical to life – and to industry. There are countless proteins that could be engineered to treat and even cure serious diseases and cellular dysfunctions.

19 May 2026