Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "Geraniol attenuates oxidative stress and neuroinflammation-mediated cognitive impairment in D galactose-induced mouse aging model."

12 Apr 2024

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease.

10 Apr 2024

Researchers identify the most harmful modifiable risk factors for dementia

Researchers from the Nuffield Department of Clinical Neurosciences at the University of Oxford have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

10 Apr 2024

Network analysis reveals subtle changes associated with subjective cognitive decline

We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it off as a normal part of aging.

9 Apr 2024

Gut-friendly psychobiotics could brighten moods and fight depression

Review uncovers that psychobiotics may offer supportive treatment for depression by restoring gut microbiome balance and positively influencing the microbiome-gut-brain axis, which is crucial for mental health and well-being.

8 Apr 2024

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

5 Apr 2024

Hypertension linked to higher dementia risk in middle-aged patients

Study investigates the relationship between hypertension in middle-aged individuals and the increased risk of developing dementia, utilizing the CAIDE score for dementia risk prediction in a cohort of white Argentinian hypertensive patients.

4 Apr 2024

Unlocking the secrets of long-lived RNAs in brain cells

After two decades in the United States, Martin Hetzer returned home to Austria in 2023 to become the 2nd President of the Institute of Science and Technology Austria (ISTA).

4 Apr 2024

UCL and Oxford lead major dementia diagnosis trials

Thousands of people in the UK are to take part in countrywide trials to identify accurate and quick blood tests that can diagnose dementia, led by research teams at UCL and Dementias Platform UK, based at the University of Oxford.

4 Apr 2024

Study evaluates the feasibility of discontinuing CLL specialist care

A study published today in Blood Advances showed that among patients in Denmark who had slow-growing chronic lymphocytic leukemia (CLL) with no symptoms and a low risk for ever needing treatment, those who stopped seeing their doctors for specialized follow-up had fewer hospital visits, fewer infections, and similar survival after three years compared to those who continued to undergo specialized follow-up.

4 Apr 2024

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Study reviews the advancements in pharmacological treatments for neuropsychiatric syndromes in neurodegenerative disorders, discussing the complexities of managing symptoms such as depression, disinhibition, apathy, psychosis, and agitation to improve patient care.

3 Apr 2024

Earlier menopause combined with high cardiovascular risk linked to cognitive problems later

Earlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory problems later, according to a new study published in the April 3, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Researchers find a promising approach to remove amyloid plaques in Alzheimer's disease

Alzheimer's disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline.

3 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Ultrasound alone improves cognitive function in neurodegenerative disorders, UQ study finds

University of Queensland researchers have found targeting amyloid plaque in the brain is not essential for ultrasound to deliver cognitive improvement in neurodegenerative disorders.

2 Apr 2024

Smartphone app shows promise in detecting early signs of frontotemporal dementia

UCSF-led research shows smartphone cognitive testing is comparable to gold-standard methods; may detect FTD in gene carriers before symptoms start.

1 Apr 2024

Study reveals protein structure similarities in Alzheimer's and Down syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

29 Mar 2024

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

28 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Alzheimer's Disease News and Research

Further Reading

Geraniol alleviates cognitive decline in D-galactose-induced aging mice

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Researchers identify the most harmful modifiable risk factors for dementia

Network analysis reveals subtle changes associated with subjective cognitive decline

Gut-friendly psychobiotics could brighten moods and fight depression

Human neuron model identifies potential therapeutic targets for Alzheimer's disease

Hypertension linked to higher dementia risk in middle-aged patients

Unlocking the secrets of long-lived RNAs in brain cells

UCL and Oxford lead major dementia diagnosis trials

Study evaluates the feasibility of discontinuing CLL specialist care

New treatments in sight for challenging neuropsychiatric symptoms in neurodegenerative diseases

Earlier menopause combined with high cardiovascular risk linked to cognitive problems later

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Researchers find a promising approach to remove amyloid plaques in Alzheimer's disease

Atomic-level structural models of enzymes provide disease insights

Ultrasound alone improves cognitive function in neurodegenerative disorders, UQ study finds

Smartphone app shows promise in detecting early signs of frontotemporal dementia

Study reveals protein structure similarities in Alzheimer's and Down syndrome

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Genetic and lifestyle factors linked to brain network aging, study reveals

Aneuro: A Year of Neuroscience in Review eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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