Angiogenesis News and Research

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Angiogenesis is blood vessel formation. Tumor angiogenesis is the growth of new blood vessels that tumors need to grow. This is caused by the release of chemicals by the tumor.

New anti-inflammatory compound acts as 'surge protector' to reduce cancer growth

A new anti-inflammatory compound developed at the University of California, Davis, acts as a "surge protector" to suppress inflammation and reduce cancer growth, at least in mouse models of cancer.

17 Jan 2019

Identifying genetic factors that lead to squamous cell carcinoma

Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent of patients, the disease will metastasize and spread throughout the body, making it difficult to treat.

14 Jan 2019

Researchers find new way to cut the power of tumors

Instead of tackling tumors head-on, an international team of researchers from the University of Geneva and the Amsterdam UMC, location VUmc in Amsterdam has chosen to regulate their vascularization by intervening with cellular receptor that is overexpressed specifically in cancer blood vessels.

20 Dec 2018

Findings may open up new ways to treat dwarfism and other ER-stress-related conditions

Pseudoachondroplasia (PSACH) is a severe inherited dwarfing condition characterized by disproportionate short stature, joint laxity, pain, and early onset osteoarthritis.

12 Dec 2018

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.

10 Dec 2018

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

The placenta offers an abundant source of placenta-derived mesenchymal stem cells (pMSCs), which a new study has shown can readily form cell sheets that could be implanted in children with congenital heart defects and offer benefits for heart repair and regeneration compared to commonly used synthetic material-based scaffolds. Congenital heart disease is the leading cause of birth-defect-related illness and death.

9 Dec 2018

Improving blood vessel growth could help mitigate health problems arising from obesity

New research led by York University's Faculty of Health shows that inhibiting a protein within blood vessels stimulates new blood vessel growth, resulting in healthier fat tissue and lower blood sugar levels.

5 Dec 2018

Using Pre-Clinical Imaging to Detect Cancer

In this interview, Émilie Beaulieu Ouellet, Application Scientist for life science imaging at Photon Etc talks to New-Medical about their range of preclinical infrared imagers and how they can allow cancer detection.

From Photon etc. 27 Nov 2018

Promising technology could improve detection, diagnosis of fatal ovarian cancer

Ovarian cancer claims the lives of more than 14,000 in the U.S. each year, ranking fifth among cancer deaths in women.

14 Nov 2018

UCV researchers discover the influence of exosomes on age-related macular degeneration

Researchers of the Neurobiology and Neurophysiology team of the Medicine Faculty at Valencia Catholic University, headed by Jorge Bacia, have discovered that exosomes - microscopic extracellular vesicles that are released by all cells - from the retinal pigment epithelium lead to cases of neovascularization, a finding which could be closely related to similar processes in age-related macular degeneration.

2 Nov 2018

FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma

EUSA Pharma welcomes the news that FOTIVDA (tivozanib) is expected to be included in the upcoming European Society of Medical Oncology clinical practice guidelines for advanced renal cell carcinoma, anticipated to be published at the end of this year.

22 Oct 2018

Incyte announces Phase 2 FIGHT-202 trial data in patients with cholangiocarcinoma

Incyte Corporation announces updated data from its ongoing Phase 2 FIGHT-202 trial evaluating pemigatinib (INCB54828), its selective fibroblast growth factor receptor (FGFR) inhibitor, in patients with advanced/metastatic or surgically unresectable cholangiocarcinoma (bile duct cancer) who failed at least one previous treatment.

22 Oct 2018

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Exelixis, Inc. today announced results from two analyses evaluating the effect of PD-L1 expression or prior treatment with immune checkpoint inhibitors on the efficacy of cabozantinib in patients with advanced renal cell carcinoma (RCC). The findings are being presented this week at the European Society for Medical Oncology 2018 Congress being held October 19-23 in Munich, Germany.

22 Oct 2018

Researchers receive $1.2 million grant to test potential treatment for metastatic breast cancer

A team of Medical University of South Carolina Hollings Cancer Center researchers received a three-year, $1.2 million grant from the U.S. Department of Defens to test a potential therapeutic antibody that could block breast cancer growth with fewer side effects, opening up potential for future drug development.

5 Oct 2018

Scientists perform successful trial of new antibiotic on cancer reoccurrence after surgery

SCIENTISTS fighting cancer have carried out the first successful trial of the effects of the antibiotic Doxycycline on cancer reoccurrence in patients after surgery.

3 Oct 2018

UB receives £1.78 million to find new therapies for treating heart failure and diabetes

The University of Birmingham has been awarded £1.78 million by the Wellcome Trust for research aimed at finding new therapies to treat diseases such as heart failure, diabetes and neurodegenerative disorders.

29 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Exelixis, Inc. today announced that its partner Ipsen Biopharmaceuticals Canada Inc. received approval from Health Canada of CABOMETYX® tablets for the treatment of adults with advanced renal cell carcinoma who have received prior vascular endothelial growth factor targeted therapy.

19 Sep 2018

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

Many eye diseases, including diabetic retinopathy and macular degeneration, exhibit increased permeability of blood vessels in the macular (central) portion of the retina leading to abnormal fluid accumulation and vision loss.

14 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

Angiogenesis News and Research

Further Reading

New anti-inflammatory compound acts as 'surge protector' to reduce cancer growth

Identifying genetic factors that lead to squamous cell carcinoma

Researchers find new way to cut the power of tumors

Findings may open up new ways to treat dwarfism and other ER-stress-related conditions

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

Improving blood vessel growth could help mitigate health problems arising from obesity

Using Pre-Clinical Imaging to Detect Cancer

Promising technology could improve detection, diagnosis of fatal ovarian cancer

UCV researchers discover the influence of exosomes on age-related macular degeneration

FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma

Incyte announces Phase 2 FIGHT-202 trial data in patients with cholangiocarcinoma

Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma

Researchers receive $1.2 million grant to test potential treatment for metastatic breast cancer

Scientists perform successful trial of new antibiotic on cancer reoccurrence after surgery

UB receives £1.78 million to find new therapies for treating heart failure and diabetes

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma

Study: aPKC inhibitors may provide new therapeutic option for blinding eye diseases

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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