Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

Competency-based cardiac imaging delivery is needed for effective and efficient patient care, according to a European Society of Cardiology (ESC) statement published today in European Heart Journal, a journal of the ESC.

25 Aug 2023

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

18 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Copy number profiling provides insight as to why prostate cancer may become lethal

Researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients.

16 Aug 2023

PSMA PET/CT can diagnose advanced prostate cancer in elderly patients without biopsy

In elderly patients with suspected prostate cancer, PSMA PET/CT can diagnose advanced disease and aid in therapy selection without the need for a biopsy.

14 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19.

10 Aug 2023

Myelodysplastic syndromes are commonly misdiagnosed, study finds

Blood disorders known as myelodysplastic syndromes/neoplasms (MDS) are difficult to diagnose – and are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences, according to researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations.

8 Aug 2023

AI-based predictive tool could help guide treatment of cancer

Researchers at Dana-Farber Cancer Institute have created an AI-based tool that uses tumor gene sequencing data to predict the primary source of a patient's cancer.

7 Aug 2023

Similarities in gene expression between post-mortem and living human brains

Researchers compare human prefrontal cortex gene expression between living and post-mortem samples.

7 Aug 2023

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

An accepted manuscript published in the American Journal of Roentgenology (AJR) found that deploying a radiomic-based model with T2-weighted MRI data could increase diagnostic accuracy for pediatric Crohn disease (CD).

3 Aug 2023

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

A group of researchers investigated single-molecule electrical detection of ribonucleic acid (RNA) cancer biomarkers.

3 Aug 2023

Liquid biopsy may be used to identify gene mutations in pediatric arteriovenous malformations

A study presented today at the Society of NeuroInterventional Surgery's (SNIS) 20th Annual Meeting indicated that it may be possible to use a less invasive technique to identify the gene mutations responsible for some arteriovenous malformations (AVMs) in pediatric patients.

2 Aug 2023

UC San Diego team reports new insights on pelvic floor muscle dysfunction

University of California San Diego researchers are leading a team reporting new insights in Science Translational Medicine on pelvic floor muscle (PFM) dysfunction, which is one of the key risk factors for pelvic floor disorders which impact close to a quarter of women in the U.S.

2 Aug 2023

Review studies relationships between vitamin E intake or circulating α-tocopherol and various health outcomes

In a recent study, researchers examined the relationships between vitamin E or circulating α-tocopherol intake and health outcomes using a meta-analyses.

2 Aug 2023

New research sheds light on gut-kidney axis in diabetes and diabetic nephropathy

Researchers explored gut microbiota composition to evaluate the association between the microbes and diabetic clinical phenotypes.

2 Aug 2023

CHLA researcher to lead a new study on liquid biopsy for diagnosing ocular cancer in children

Just a handful of years ago, retinoblastoma had the medical field stumped. This pediatric eye cancer cannot be directly biopsied, which means clinicians must diagnose the disease by visual examination and imaging.

1 Aug 2023

Diagnosis of rare inherited metabolic condition in a Sumatran orangutan

Researchers from Indiana University School of Medicine have diagnosed a Sumatran Orangutan at the Indianapolis Zoo with a rare genetic disease called Alkaptonuria.

27 Jul 2023

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Houtan Noushmehr, Ph.D., a researcher at Henry Ford Health, has been awarded a prestigious R01 grant of nearly $2.9M from the National Institutes of Health (NIH) to support a research project titled, "Circulating cell-free DNA methylation as an accurate tool for detection and clinical follow-up of glioma."

27 Jul 2023

Biopsy News and Research

Further Reading

ESC statement: Competency-based cardiac imaging delivery needed for effective patient care

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Pig kidney xenotransplantation continues to function well after 32 days

Copy number profiling provides insight as to why prostate cancer may become lethal

PSMA PET/CT can diagnose advanced prostate cancer in elderly patients without biopsy

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Myelodysplastic syndromes are commonly misdiagnosed, study finds

AI-based predictive tool could help guide treatment of cancer

Similarities in gene expression between post-mortem and living human brains

Radiomic and clinical data could help increase diagnostic accuracy for pediatric Crohn disease

Fully electrical proof-of-concept biosensor for detecting RNA cancer biomarker sequences in solution at the single-molecule level

Liquid biopsy may be used to identify gene mutations in pediatric arteriovenous malformations

UC San Diego team reports new insights on pelvic floor muscle dysfunction

Review studies relationships between vitamin E intake or circulating α-tocopherol and various health outcomes

New research sheds light on gut-kidney axis in diabetes and diabetic nephropathy

CHLA researcher to lead a new study on liquid biopsy for diagnosing ocular cancer in children

Diagnosis of rare inherited metabolic condition in a Sumatran orangutan

Henry Ford Health researcher wins grant to study circulating cell-free DNA methylation as a tool for glioma detection

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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