CAR T cell News and Research

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Research seeks to fight organ rejection in kidney transplant patients

While waiting on the transplant list, most patients are extremely sick and fighting just to stay alive.

1 Aug 2019

CAR-T cells used to target glioblastoma

Immunotherapy is the new weapon against cancers and building upon existing research, a team of researchers from the Massachusetts General Hospital have devised a way to make immunotherapy more effective in a deadly and common form of brain cancer called glioblastoma.

24 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Henry Ford Cancer Institute treats its first patient with CAR T-cell therapy

Henry Ford Cancer Institute has treated its first patient with CAR T-cell therapy, an approach that uses engineered cells from a patient's immune system to destroy cancer.

18 Jun 2019

Cancer researchers discover new functions for common oncogene MYC

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year.

30 May 2019

Genetically eliminating TOX factors improves eradication of solid tumors in CAR T model

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.

28 May 2019

Neurological Side Effects of CAR T-Cell Therapy Revealed

Researchers at Brigham and Women’s Hospital quantified the neurological symptoms associated with CAR T-cell therapy and found that 77 percent of patients receiving the treatment experienced at least one neurological side effect.

16 May 2019

Quanterix announces $50,000 in grants to support promising oncology research

Quanterix announced a call for proposals for a new Accelerator Grant Program.

From Quanterix 16 May 2019

Researchers develop a new approach to targeting tumors and metastases

The spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is the main cause of cancer deaths worldwide.

7 May 2019

Advance in breakthrough cancer treatment eliminates serious side effects

An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows.

22 Apr 2019

Unusually small antibodies could help CAR T-cell therapies to kill solid tumors

In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. I

12 Apr 2019

Scientists visualize immune cells fighting blood cancer for the first time

When cancer escapes the immune system, our defenses are rendered powerless and are unable to fight against the disease.

8 Apr 2019

HCA Healthcare UK introduces ground-breaking new blood cancer treatment

HCA Healthcare UK has announced the launch of CAR T-cell therapy - a ground-breaking new blood cancer treatment which will be available to eligible patients with Diffuse Large B-Cell Lymphoma and Acute Lymphoblastic Leukaemia.

3 Apr 2019

Tumor biomarker EpCAM shown to be promising target for cancer immunotherapy

Researchers have shown that cancer immunotherapy targeting the tumor biomarker epithelial cell adhesion molecule is safe and nontoxic in mice and can significantly delay tumor formation and growth.

28 Mar 2019

Heating tumors during CAR T-cell therapy can enhance treatment's success, study suggests

A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success.

28 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells.

14 Mar 2019