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Using Spherical Nucleic Acids to Track and Treat Disease

Spherical nucleic acids are structures that are made by taking a nanoparticle template and using chemistry to arrange short strands of DNA or RNA on the surface of those particles. The spherical core of the nanoparticle creates a spherical arrangement of DNA or RNA, similar to tiny little balls of nucleic acids.

From Pittcon 1 Mar 2017

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

The IncuCyte® live-cell analysis platform from Essen BioScience will be showcased at the upcoming AACR conference, booth #1365.

From Sartorius 22 Feb 2017

Researchers develop computer machine-learning model to predict remission or relapse in AML patients

Researchers have developed the first computer machine-learning model to accurately predict which patients diagnosed with acute myelogenous leukemia, or AML, will go into remission following treatment for their disease and which will relapse.

9 Feb 2017

Researchers identify E. coli bacteria linking Crohn's disease to spondyloarthritis

Patients with Crohn's disease, a type of inflammatory bowel disease (IBD) that causes abdominal pain and diarrhea, can also experience joint pain.

9 Feb 2017

Exosome isolation using ultracentrifugation

In the outpatient clinic and lab, our research studies aim to understand biological functions of exosomes and membrane particles.

From Beckman Coulter Life Sciences - Centrifugation 9 Feb 2017

Researchers develop rapid screening method to select promising nanoparticles for medicine

The use of nanoparticles — small, virus-sized elements developed under laboratory conditions — is increasingly widespread in the world of biomedicine. This rapidly-evolving technology offers hope for many medical applications, whether for diagnosis or therapies.

3 Feb 2017

Single Molecule Detection of Proteins in Single Cells

We developed this technology almost 10 years ago. It was developed after a key experiment was carried out by David Rissin, who was a PhD candidate in my laboratory at the time.

From Pittcon 3 Feb 2017

Service to screen for DNA damaging compounds released by Merck

Merck, a leading science and technology company, has introduced CAN MultiFlow™ screening services to more accurately predict genotoxic and mode of action* properties of substances, ingredients and drug compounds. Offered through its BioReliance® testing facilities, Merck will be the first company to provide this service in the United States.

20 Jan 2017

Equipment for single-cell genomics launched by Illumina and Bio-Rad

Illumina, Inc. and Bio-Rad Laboratories, Inc. today announced the launch of the Illumina® Bio-Rad® Single-Cell Sequencing Solution at the J.P. Morgan Healthcare Conference. The comprehensive solution is the first next-generation sequencing (NGS) workflow for single-cell analysis, providing researchers the ability to investigate the coordinated contribution of individual cells in tissue function, disease progression, and therapeutic response.

From Illumina, Inc. 12 Jan 2017

Qioptiq to unveil new wavelength pairing for iFLEX-Gemini laser series at SPIE Photonics West

Qioptiq, an Excelitas Technologies Company and global technology leader in delivering innovative optical and photonic solutions, will present its new wavelength pairing for the popular iFLEX-Gemini Dual-Wavelength Laser Series with new 488/647nm wavelengths at SPIE Photonics West.

From Excelitas Technologies 20 Dec 2016

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response.

17 Dec 2016

UAB researchers show how aging and excess dietary fat lead to heart failure

In mouse experiments, University of Alabama at Birmingham researchers have shown how aging and excess dietary fat create signals that lead to heart failure after a heart attack.

17 Nov 2016

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer

Tumor cells collected during the removal of a cancerous bladder and - in some cases - transplanted into mice with weakened immune systems, could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care for patients with this common cancer, according to a study published online on Oct. 24, 2016, in Scientific Reports.

24 Oct 2016

Beckman Coulter Life Sciences introduces ClearLLab LS Lymphoid Screen Reagent for faster L&L analysis

Beckman Coulter Life Sciences further demonstrates its expertise in clinical flow cytometry with the launch of ClearLLab LS Lymphoid Screen Reagent, Europe’s first CE-marked 10-colour, 12 antibody reagent combination for leukaemia and lymphoma analysis.

20 Oct 2016

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry.

21 Sep 2016

Sanford wins $11.7 million NIH grant to translate laboratory cancer research into clinical trials

The Cancer Biology Research Center at Sanford Research is the recipient of a five-year, nearly $11.7 million grant from the National Institutes of Health to translate laboratory research into clinical trials for head and neck and pediatric cancers.

20 Sep 2016

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans.

25 Aug 2016

Adaptive Biotechnologies demonstrates use of high-throughput sequencing platform for MRD

Adaptive Biotechnologies, the leader in combining next-generation sequencing (NGS) and expert bioinformatics to profile T- and B-cell receptors of the adaptive immune system, and collaborators will be presenting five studies demonstrating how Adaptive’s high-throughput sequencing platform enables diagnosis, detection and assessment of prognosis in hematological malignances and has increased sensitivity over flow cytometry.

16 Jun 2016

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial.

6 Jun 2016

Vegetable-based polyphenol enhances wound healing

A research group led by Osaka University found a plant-based polyphenol, promotes the migration of Mesenchymal Stem Cells (MSCs) in blood circulation and accumulates them in damaged tissues to improve wound healing. It is anticipated that the results will be used for stem cell treatments for cutaneous disorders associated with various damage and lesions.

21 Apr 2016