Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.
High affinity antibodies isolated to safely target Claudin 6-positive tumors

High affinity antibodies isolated to safely target Claudin 6-positive tumors

Researchers develop a new approach to better understand the biology of polycystic kidney disease

Researchers develop a new approach to better understand the biology of polycystic kidney disease

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

Insilico Medicine launches a 6th generation Intelligent Robotics Drug Discovery Laboratory

PhoreMost and Boehringer Ingelheim enter multi-project drug discovery collaboration

PhoreMost and Boehringer Ingelheim enter multi-project drug discovery collaboration

Incurable liver disease could be reversed with a single drug

Incurable liver disease could be reversed with a single drug

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

New method uses artificial DNA to target and kill cancer cells

New method uses artificial DNA to target and kill cancer cells

CN Bio appoints Dr Paul Brooks as Chief Executive Officer

CN Bio appoints Dr Paul Brooks as Chief Executive Officer

New imaging agent lights the way for surgeons during lung cancer surgery

New imaging agent lights the way for surgeons during lung cancer surgery

PhoreMost and ThinkCyte collaborate to advance AI based drug discovery

PhoreMost and ThinkCyte collaborate to advance AI based drug discovery

New clue may explain why women are at greater risk for Alzheimer's disease

New clue may explain why women are at greater risk for Alzheimer's disease

People with cocaine- and opioid-use disorders infected with COVID-19 have greater risk of endocarditis

People with cocaine- and opioid-use disorders infected with COVID-19 have greater risk of endocarditis

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Structural studies pave the way for cancer drugs that could target only mutated versions

Structural studies pave the way for cancer drugs that could target only mutated versions

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Researchers seek to reduce Chikungunya virus-caused joint pain with new drug

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Liver cancer study could help improve the safety of certain gene therapies for hemophilia

Pre-Plated Assay Solutions That Can Help Accelerate Biotech

Pre-Plated Assay Solutions That Can Help Accelerate Biotech

Collaborative work unravels hidden molecular secrets of age-related diseases

Collaborative work unravels hidden molecular secrets of age-related diseases

Scaling up the production of customized immune cells for drug development and testing

Scaling up the production of customized immune cells for drug development and testing