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Newly discovered protein regulates molecular motors in response to light

Single-celled algae and animal sperm cells are widely separated in evolution but both swim in the same way, by waving their protruding hairs, called cilia or flagella. Motion is driven by molecular motors, complex assemblies of proteins that exert a force when changing shape.

1 Mar 2021

New method to enhance images of the SARS-CoV-2 virus

Researchers report a method of removing noise from high-resolution transmission electron microscopy images using probabilistic generative models.

28 Feb 2021

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

A new study by researchers at Brookhaven National Laboratory and Stony Brook University in the U.S. describes the key interaction between the viral envelope (E) protein and the human cell junction protein, PALS1. The latter is necessary to establish and maintain cell polarity and tight junctions between cells.

26 Feb 2021

New approach harnesses disease-causing proteins to combat cancer

Over many decades now, traditional drug discovery methods have steadily improved at keeping diseases at bay and cancer in remission. And for the most part, it's worked well.

26 Feb 2021

New technique helps detect biocontaminants in environmental water samples

Carolina Belenguer and EnricPellicer, from the Department of Analytical Chemistry at the University of Valencia, have developed in the last year a new method for the detection of polychlorinated biphenyls (PCBs) in environmental water samples.

25 Feb 2021

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

The clinical phenotype of COVID-19, caused by SARS-CoV-2, is remarkable for its wide range of severity among individual patients. Genetic variations are known to mediate part of these differences. To examine these differences, researchers in a new study used human induced pluripotent stem cells (iPSCs) from different genetically diverse individuals. These cells are used to model genetic disease since they contain the donor’s genetic information. Researchers use a panel of iPSCs from over 500 individuals. The researchers preferred undifferentiated iPSCs to reduce the time required to differentiate them, especially since infection is not always reliable.

25 Feb 2021

Researchers use powerful X-rays to analyze brain tissues of schizophrenia patients

Schizophrenia, a chronic, neurological brain disorder, affects millions of people around the world. It causes a fracture between a person's thoughts, feelings and behavior.

24 Feb 2021

Two potent SARS-CoV-2 neutralizing antibodies effective against B.1.351 and B.1.1.7 variants

By analyzing the cryoEM structures of antibodies against the SARS-CoV-2 virus, researchers report that the neutralizing capabilities of two antibodies are not affected by new strains as these antibodies target regions of the virus away from the ACE2 binding regions.

23 Feb 2021

Propranolol can be used to treat cerebral cavernous malformations

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi", resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterized by misshapen blood vessels in the brain and elsewhere.

23 Feb 2021

What makes viruses infectious?

In this interview, News-Medical spoke to Professor Peter Stockley about his latest research that looked at what makes viruses infectious.

23 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

COVID-19 vaccine candidate shows potential against SARS-CoV-2 and potential future zoonotic coronaviruses

A new study sheds light on the threat posed by future zoonotic coronaviruses to make similar leaps across species barriers to infect human beings and cause other pandemics.

22 Feb 2021

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

The mapping of O-glycosites requires instruments that can support electron transfer dissociation (ETD) fragmentation. In a new study published on the bioRxiv preprint server, researchers report their results on whether O-glycosylation patterns affect immunogens for vaccine development.

18 Feb 2021

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

Scientists at EMBL Heidelberg and at the Zentrum für Infektiologie at Heidelberg University Hospital have succeeded for the first time in imaging HIV during transport into the nucleus of an infected cell.

18 Feb 2021

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Using simulations, a team of researchers in the U.S. found that the glycan at position N343 of the SARS-CoV-2 spike protein’s receptor-binding domain (RBD) helps in its opening. A mechanism that aids its binding to the host cell receptor.

18 Feb 2021

Scientists reveal the structure of glutamate transporter in our cells

For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another.

18 Feb 2021

Wearable chemical sensor can measure the concentration of lactate in sweat

With the seemingly unstoppable advancement in the fields of miniaturization and materials science, all sorts of electronic devices have emerged to help us lead easier and healthier lives.

18 Feb 2021

Scientists reveal the shape of glutamate transporter in human cells

A University of Sydney-led international team of scientists has revealed the shape of one of the most important molecular machines in our cells the glutamate transporter, helping to explain how our brain cells communicate with one another.

18 Feb 2021

New insights on structural biology may help design more efficient antibodies

In structural biology, some molecules are so unusual they can only be captured with a unique set of tools.

18 Feb 2021

New collaborative project to study the complex roles of lipids in health, disease

A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

17 Feb 2021

Electron News and Research

Newly discovered protein regulates molecular motors in response to light

New method to enhance images of the SARS-CoV-2 virus

Structure of SARS-CoV-2 envelope protein-epithelial cell junction protein complex explains virulence

New approach harnesses disease-causing proteins to combat cancer

New technique helps detect biocontaminants in environmental water samples

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

Researchers use powerful X-rays to analyze brain tissues of schizophrenia patients

Two potent SARS-CoV-2 neutralizing antibodies effective against B.1.351 and B.1.1.7 variants

Propranolol can be used to treat cerebral cavernous malformations

What makes viruses infectious?

Study reveals mechanism for translation of maternally inherited mitochondrial genome

COVID-19 vaccine candidate shows potential against SARS-CoV-2 and potential future zoonotic coronaviruses

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

Researchers use high-resolution imaging to observe HIV infection process in the cell nucleus

A glycan controls how SARS-CoV-2’s spike protein opens, study finds

Scientists reveal the structure of glutamate transporter in our cells

Wearable chemical sensor can measure the concentration of lactate in sweat

Scientists reveal the shape of glutamate transporter in human cells

New insights on structural biology may help design more efficient antibodies

New collaborative project to study the complex roles of lipids in health, disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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