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Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

Now, a new preprint research paper describes a chimpanzee adenovirus-vectored vaccine that, when administered intranasally in rhesus macaques, led to a robust immune response and demonstrated protection against infection by the virus that causes COVID-19, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The preprint is published on the bioRxiv server.

1 Feb 2021

Comprehensive review details the evolution of surgical microscopes

A clear view of anatomical structures is vital for the success of surgery--especially in microsurgery where narrow anatomical cavities or proximity to vulnerable organs and tissues can pose significant risks to patient health.

5 Jan 2021

SARS-CoV-2 infected alveolar type-II lung cells show senescence

Using monoclonal antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and senescent markers, researchers provide evidence that virus-infected lung cells acquire characteristics of cellular senescence, which also leads to expression of proinflammatory cytokines.

5 Jan 2021

Researchers discover novel mechanism by which cells turn over mitochondria

Mitochondria are cellular organelles that generate most of the energy cells need to function, and thus play an important role in maintaining cell health.

21 Dec 2020

SARS-CoV-2 deactivation on surfaces in 30 seconds with a copper paste

In a recent bioRxiv preprint paper, a team of researchers shows the possibility of using copper, in a new conformation, for effectively killing microbes immediately.

18 Nov 2020

Study investigates similarities between network of galaxies and network of neuronal cells in the human brain

In their paper published in Frontiers of Physics, Franco Vazza (astrophysicist at the University of Bologna) and Alberto Feletti (neurosurgeon at the University of Verona) investigated the similarities between two of the most challenging and complex systems in nature: the cosmic network of galaxies and the network of neuronal cells in the human brain.

17 Nov 2020

Microsurgery improves outcomes in patients experiencing paralysis from Parsonage-Turner Syndrome

Orthopedic surgeons at Hospital for Special Surgery performed successful microsurgery to repair damaged nerves and restore muscle strength and movement to patients experiencing paralysis from Parsonage-Turner Syndrome, according to a study published online ahead of print in The Journal of Hand Surgery.

27 Oct 2020

3D imaging of SARS-CoV-2 infection in ferrets using light sheet microscopy

Researchers from the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health demonstrate the ability to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in 3D tissue samples in ferrets. This will allow the detection of infection patterns in tissues and their interrelations.

20 Oct 2020

Study could offer important clues on factors affecting human microbiome rhythms

Nearly every organism hosts a collection of symbiotic microbes--a microbiome. It is now recognized that microbiomes are major drivers of health in all animals, including humans, and that these symbiotic systems often exhibit strong daily rhythms.

20 Oct 2020

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Scientists from Russia and Switzerland have probed into nanostructures covering the corneas of the eyes of small fruit flies. Investigating them the team learned how to produce the safe biodegradable nanocoating with antimicrobial, anti-reflective, and self-cleaning properties in a cost-effective and eco-friendly way.

14 Oct 2020

Study provides a new depth of resolution to understand single gene disorders

Traditionally, geneticists divide disorders into "simple," where a single gene mutation causes disease, or complex, where mutations in many genes contribute modest amounts. A new study suggests that the truth is somewhere in between.

12 Oct 2020

Proteolytic activation of the SARS-CoV-2 spike S1/S2 site

In a recent paper published on the bioRxiv preprint server, Cornell University researchers study the proteolytic activation of the SARS-CoV-2 spike sites, re-evaluating the furin cleavage.

6 Oct 2020

Using virus-like particles to study SARS-CoV-2 assembly, budding, and entry

In a recent preprint paper published on the bioRxiv server, researchers from the Purdue Institute of Inflammation, Immunology, and Infectious Disease, Purdue University, West Lafayette, IN, discuss their efforts to assess the 4 SARS-CoV-2 structural proteins for their ability to produce VLPs from human cells to create a competent system for BSL-2 studies of SARS-CoV-2.

6 Oct 2020

Cats and dogs are low risk for SARS-CoV-2 transmission to humans

Researchers from the College of Veterinary Medicine and Biomedical Sciences, Colorado State University studied the possible transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among domestic cats and dogs.

5 Oct 2020

Study shows how fiber shapes the structure of plant cell walls

The secret of how fibre shapes the structure of plant cell walls has been revealed, with potentially wide-ranging applications ranging from nutrition and health to agriculture.

18 Sep 2020

Michigan sees increasing EEE cases

In the United States, the Michigan Department of Health and Human Services (MDHHS) urge people to stay indoors, especially after dusk. Health officials have confirmed 22 horse cases of Eastern Equine Encephalitis (EEE), and one suspected human case.

17 Sep 2020

New images capture startlingly high SARS-CoV-2 viral loads

Now, a team of scientists from the University of North Carolina at Chapel Hill School of Medicine produced striking images in respiratory tract cultures of the infectious form of the SARS-CoV-2 produced by infected epithelial cells.

16 Sep 2020

Moving towards a new age of personalized, cell-based interceptive medicine for Europe

Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

7 Sep 2020

Evidence of SARS-CoV-2 coronavirus particles in heart tissue

Researchers in Milan, Italy, have identified the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the heart tissue of deceased coronavirus disease 2019 (COVID-19) patients who had died from respiratory failure, without showing any signs of cardiac involvement.

27 Aug 2020

Loss of supporting cells in olfactory epithelium causes loss of smell in COVID-19

In the current pandemic of COVID-19, many patients have reported symptoms of loss of smell and taste. The cellular basis of this phenomenon has not been satisfactorily explained so far. However, a new study published in the Briefings in Bioinformatics in August 2020 shows how this symptom is related to viral pathogenesis.

23 Aug 2020