Pharmacokinetics News and Research

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The term pharmacokinetics is derived from the ancient Greek words “pharmakon” and “kinetikos”, meaning “drug” and “putting in motion” respectively. It is one of the main branches of pharmacology, and refers to the way that the body reacts on and affects a pharmaceutical substance in the body.

Are men or women impacted more by adverse reactions to prescription drug treatments?

Recently, researchers presented an overview of sex-based differences in adverse drug reactions (ADRs) based on epidemiology, technique, and underlying mechanism data.

11 Oct 2022

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study led by Oregon State University suggests.

28 Sep 2022

Investigating a potential new treatment for glioblastomas

A research question posed in Pankaj Desai's lab has led to a decade of research, a clinical trial and major national funding to further investigate a potential new treatment for the most deadly form of brain tumors.

23 Sep 2022

Recent developments in the use of nanoparticles to deliver drugs to the brain via intranasal administration

Scientists have recently reviewed research articles related to the application of inorganic nanoparticles in delivering drugs to the brain through the intranasal route.

7 Sep 2022

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Announcing a new article publication from Acta Pharmaceutica Sinica B. Constitutively activated G proteins caused by specific mutations mediate the development of multiple malignancies.

5 Sep 2022

Temporo-spatial pharmacometabolomics method to evaluate microregional effect of OLZ on brain tissue

Announcing a new article publication from Acta Pharmaceutica Sinica B. The brain is the most advanced organ with various complex structural and functional microregions.

5 Sep 2022

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Synexa is an industry-leading biomarker and large molecule bio analytic research service provider. In this interview, NewsMedical speaks with Natalie Strickland, a principal scientist at Synexa, about alternative approaches to flow cytometry.

From Synexa Life Sciences BV 5 Sep 2022

Antiviral activity of favipiravir against Zika and SARS-CoV-2 in cynomolgus macaques

A new study determines the antiviral efficacy of favipiravir against ZIKV and SARS-CoV-2 infections.

4 Sep 2022

The safety, tolerability, and pharmacokinetics of a muco-trapping monoclonal antibody delivered by inhalation

Researchers conducted a phase I clinical trial of IN-006, an inhaled monoclonal antibody treatment for COVID-19.

24 Aug 2022

Next-generation monoclonal antibody prevents malaria

Researchers investigate the pharmacokinetics and safety of L9LS, a monoclonal antibody to prevent malaria.

9 Aug 2022

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

Researchers evaluated the efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell cultures.

2 Aug 2022

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Researchers review current developments in preclinical studies associated with recombinant ACE2 decoy receptors against coronaviruses.

31 Jul 2022

Novel nanoligomer approach to treat severe COVID-19

Researchers discuss the biodistribution and safety of a novel nanoligomer SBCoV207, which was used to targeted miR-2392 in a murine model.

17 Jul 2022

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.

5 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

Kratom: A dangerous or beneficial plant?

A new study summarizes the traditional and modern uses of kratom, as well as its pharmacology, benefits, and adverse health impacts.

23 Jun 2022

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

In a recent study published in the Lancet, researchers evaluated the safety and efficacy of tixagevimab–cilgavimab, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) combination in patients with mild to moderate coronavirus disease 2019 (COVID-19).

8 Jun 2022

Pharmacokinetics News and Research

Further Reading

Are men or women impacted more by adverse reactions to prescription drug treatments?

Vitamin supplements can benefit cystic fibrosis patients, study suggests

Investigating a potential new treatment for glioblastomas

Recent developments in the use of nanoparticles to deliver drugs to the brain via intranasal administration

Targeting Gαq/11 may be an efficient therapeutic strategy against uveal melanoma

Temporo-spatial pharmacometabolomics method to evaluate microregional effect of OLZ on brain tissue

Alternative approaches to functional and phenotypic assays using multi-parameter flow cytometry

Antiviral activity of favipiravir against Zika and SARS-CoV-2 in cynomolgus macaques

The safety, tolerability, and pharmacokinetics of a muco-trapping monoclonal antibody delivered by inhalation

Next-generation monoclonal antibody prevents malaria

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Novel nanoligomer approach to treat severe COVID-19

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

Kratom: A dangerous or beneficial plant?

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

Novel approach to drug repurposing incorporates two-stage prediction and machine learning

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Industry Focus - Biopharma eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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