Retinoblastoma News and Research

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A retinoblastoma is a malignant tumor of the retina, occurring most often in young children below 5 years. In one of three cases it is bilateral i.e., affecting both eyes. About 250-350 new cases occur every year in the USA, in children younger than 15 years.

Air quality and residential greenness influence childhood cancer development

In a new study led by the University of Minnesota's Masonic Cancer Center and the U of M Medical School, researchers found that exposure to air pollution and vegetation may impact childhood cancer development.

21 Feb 2024

CHLA researcher to lead a new study on liquid biopsy for diagnosing ocular cancer in children

Just a handful of years ago, retinoblastoma had the medical field stumped. This pediatric eye cancer cannot be directly biopsied, which means clinicians must diagnose the disease by visual examination and imaging.

1 Aug 2023

Researchers develop a new smartphone-based tool to detect visual impairment in young children

Researchers conducted a prospective, multicenter, observational study between 14 January 2020 and 30 January 2022 in China.

30 Jan 2023

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

Researchers discover a molecule that promotes tumor cell survival in retinoblastoma

Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer.

3 Oct 2022

Research brings us closer to optimizing treatments for children with retinoblastoma

Retinoblastoma is a cancer of the eye that occurs in infants and toddlers and can lead to loss of vision, loss of one or both eyes, and even death.

26 Sep 2022

Death from retinoblastoma is more common among children in low-income countries

Children with the eye cancer retinoblastoma in a low-income country are at 16 times higher risk of dying at any time within three years of diagnosis than those in high-income countries, according to a new study published in The Lancet Global Health.

13 Jul 2022

Study finds higher risk of all-cause mortality among pediatric cancer patients in LMICs during the pandemic

During the first nine months of the COVID-19 pandemic, pediatric cancer patients from lower- and middle-income countries faced a higher risk of all-cause mortality than those in high-income countries, according to data presented at the AACR Annual Meeting 2022, held April 8-13.

11 Apr 2022

Infantile cataracts are more common and problematic than thought

Three days after Canyon Brown was born, the attending pediatrician discovered a problem.

8 Dec 2021

Researchers create new model for studying earliest stages of retinoblastoma

Scientists at St. JudeChildren's Research Hospital have created a laboratory model for studying retinoblastoma driven by inherited mutations in theRB1gene.Retinoblastoma is a rare cancer of the retina, the thin tissue inside the back of the eye.

6 Aug 2021

Candy-like models could make science more accessible to visually impaired students

About 36 million people have blindness including 1 million children. Additionally, 216 million people experience moderate to severe visual impairment. However, STEM (science, technology, engineering and math) education maintains a reliance on three-dimensional imagery for education. Most of this imagery is inaccessible to students with blindness.

29 May 2021

Cognitive outcomes in survivors of childhood cancers have been largely understudied

In a new study led by Yale Cancer Center, researchers report many survivors of childhood cancers receive systemic therapies associated with cognitive effects and chronic health conditions that may impact long-term cognitive outcomes with downstream effects on education, employment, and income.

23 Apr 2021

Proteogenomics can help determine effective treatment for head and neck squamous cell carcinoma

Proteogenomic analysis may offer new insight into matching cancer patients with an effective therapy for their particular cancer.

7 Jan 2021

Cellular senescence variations may control health and onset of age-related diseases

Researchers from Kumamoto University, Japan have proposed that cellular senescence variations during the aging process could lead to control of health and onset of age-related diseases.

27 Oct 2020

Two young scientists receive Damon Runyon-Sohn Pediatric Cancer Fellowship Award

The Damon Runyon Cancer Research Foundation has named two outstanding young scientists as recipients of the Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $500,000 to help address a critical shortage of funding for pediatric cancer research.

30 Jul 2020

Subpopulations of tumor cells may exhibit diverging behaviors from bulk tumor

Subpopulations of tumor cells may exhibit diverging behaviors from the bulk tumor due to an alternate stress response that diverts tumor cells from apoptotic death.

20 Nov 2019

Novel detection method for retinoblastoma

A retinoblastoma is a dangerous cancer often occurring in very young children, under 2, which can cause blindness or the loss of the eye. The tumor is a diffuse, gluey mass spread all over the eye. It also spreads easily. As a result of this, direct biopsy is impossible, unlike with most other tumors. Instead, eye examination by ophthalmologists (eye specialists) and ultrasound imaging are needed to make a diagnosis.

5 Nov 2019

Biomarker reveals if benign-appearing meningiomas are dangerous

A modified protein in benign-appearing meningiomas can reveal which are truly benign and which are more dangerous and require more aggressive treatment, researchers have discovered.

5 Nov 2019

Researchers discover way to find genetic tumor information of retinoblastoma

Retinoblastoma is a cancer that forms in the light-detecting cells in the back of the eye. It often appears in children under two years of age and can lead to blindness or eye removal. Most cancers are biopsied and studied so that medical research can design targeted treatments. Unfortunately, this is not possible with retinoblastoma.

4 Nov 2019

Eye disease in infants detected using smartphone app

Examining eyes in babies is difficult to say the least. Researchers at the Baylor University in Waco, Texas, have come up with a smart phone app that could help ophthalmologists detect eye diseases in infants. The results of the testing of the app were published in the latest issue of the journal Science Advances.

8 Oct 2019