Severe Acute Respiratory News and Research

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Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A startling new study reports the rapid rise to dominance of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in Italy. This strain, termed the GV clade, is characterized by a single point mutation.

2 Dec 2020

A new potential COVID-19 vaccine candidate: YF-S0

A recent study published in the journal Nature describes the safety and efficacy of a live-attenuated yellow fever 17D (YF17D) vector-based vaccine candidate expressing a non-cleavable form of the spike protein of severe acute respiratory coronavirus 2 (SARS-CoV2).

2 Dec 2020

New and sudden headaches may be a symptom of COVID-19

Researchers report a case of a young male patient who came in with a headache to an emergency room. He had increased intracranial pressure and tested positive for SARS-CoV-2, suggesting new headaches during the pandemic should not be ignored.

2 Dec 2020

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

A team of researchers at the University of Tokyo in Japan have detected a sarbecovirus, called Rc-o319, which is phylogenetically positioned in the same clade as SARS-CoV-2 in Rhinolophus cornutus bats in Japan.

2 Dec 2020

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

A new study has found that particulate matter (PM) plays a role in providing surfaces for SARS-CoV-2 transmission and interaction, enabling fomite transmission through deposition.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

Nanoengineers at the University of California San Diego have developed new and improved probes, known as positive controls, that could make it easier to validate rapid, point-of-care diagnostic tests for COVID-19 across the globe.

2 Dec 2020

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

In an article published in the journal Virus Research, a team of researchers from various US institutions discussed their study that evaluated the antiviral activity of PTC299 against a group of RNA viruses in vitro.

1 Dec 2020

Nanomedicine's giant step into the fight against the COVID-19

A recent editorial in Nature Nanotechnology discusses the enormous feat of scientific innovation, with messenger RNA (mRNA)-based vaccines developed to deliver the gene sequence of specific SARS-CoV-2 viral proteins into host cells using nanotechnology platforms.

1 Dec 2020

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Researchers in Algeria have reviewed some of the evidence suggesting that flavonols commonly found in many plants and vegetables could be used as a therapeutic approach to coronavirus disease 2019 (COVID-19).

1 Dec 2020

Does smoking increase risk of COVID-19 hospitalization?

A study conducted by UK researchers has found that patients hospitalized with coronavirus disease 2019 (COVID-19) were less likely to be current smokers than patients who had been admitted with other types of respiratory viral infections last year (2019).

1 Dec 2020

Which dietary supplements can help prevent COVID-19?

Researchers explore dietary supplement usage during the COVID-19 pandemic.

1 Dec 2020

Altered smell and taste impacts psychological wellbeing of COVID-19 survivors, study finds

A recent study discloses that loss of taste and smell sensation after infection with SARS-CoV-2 negatively impacts the quality of life and psychological wellbeing of those that recover but experience persistence of this symptom.

1 Dec 2020

Potential SARS-CoV-2 antiviral: Ionophore X-206 found to inhibit viral replication in cell cultures

In a study published in the journal Antiviral Research, researchers from Aarhus University, Denmark, report on their tests on different polyether ionophores to inhibit SARS-CoV-2 in vitro.

1 Dec 2020

SARS-CoV-2's microRNAs may have promoted its jump to humans

A new study uses machine learning to explore the small microRNAs (or miRNAs) of SARS-CoV-2 that may determine the virus's ability to successfully infect humans by altering the course of transcriptional events.

1 Dec 2020

Chinese woman still sheds SARS-CoV-2 over four months post-infection

A new study by Chinese scientists explore an unusual case of extended viral shedding in a 68-year-old woman up to four months post-infection.

1 Dec 2020

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

3D8, a 27-kDa recombinant antibody fragment, was found in autoimmune-prone Murphy Roths Large mice. The single-chain variable fragment (scFv) has the nucleic acid hydrolyzing activity and is shown to degrade DNA or mRNA of viruses in infected cells.

30 Nov 2020

Fibromyalgia during COVID-19, anxiety and pain

Early research on the impact of the COVID-19 pandemic found persistent related anxiety in the general population. Researchers in the UK hypothesized that this anxiety would be associated with increased pain in chronic pain patients diagnosed with fibromyalgia (FM).

30 Nov 2020

Good cholesterol helps SARS-CoV-2 enter cells

The researchers explained that the SARS-CoV-2 can infect human host cells after its viral spike protein (SARS-2-S) binds to a cellular surface receptor called the angiotensin-converting enzyme 2 (ACE2).

30 Nov 2020

Clonal hematopoiesis linked to severe COVID-19

Now, an international team of researchers from the USA, South Korea and Canada has found that clonal hematopoiesis is tied to the risk of severe COVID-19.

30 Nov 2020

Severe Acute Respiratory News and Research

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A new potential COVID-19 vaccine candidate: YF-S0

New and sudden headaches may be a symptom of COVID-19

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

New, improved probes could make it easier to validate rapid COVID-19 diagnostic tests

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

Nanomedicine's giant step into the fight against the COVID-19

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Does smoking increase risk of COVID-19 hospitalization?

Which dietary supplements can help prevent COVID-19?

Altered smell and taste impacts psychological wellbeing of COVID-19 survivors, study finds

Potential SARS-CoV-2 antiviral: Ionophore X-206 found to inhibit viral replication in cell cultures

SARS-CoV-2's microRNAs may have promoted its jump to humans

Chinese woman still sheds SARS-CoV-2 over four months post-infection

Nucleic acid-hydrolyzing scFv 3D8 exhibits potent antiviral effects on SARS-CoV-2

Fibromyalgia during COVID-19, anxiety and pain

Good cholesterol helps SARS-CoV-2 enter cells

Clonal hematopoiesis linked to severe COVID-19

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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