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Caltech researchers develop miniature device for use in ‘smart pills’ to diagnose and treat diseases

Researchers at Caltech have developed a prototype miniature medical device that could ultimately be used in "smart pills" to diagnose and treat diseases.

12 Sep 2017

Researchers reveal possible origin of cancer-associated fibroblasts

Researchers at Okayama University describe in Scientific Reports that cancer-associated fibroblasts — cells that play a key role in cancer progression — originate from cancer stem cells. Preventing cancer stem cells from transforming into cancer-associated fibroblast may be a promising approach towards cancer treatment.

12 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Research provides new insights into secret life of bacteria

Bacterial infections are the number one cause of death in hospital patients in the United States, and antibiotic-resistant bacteria are on the rise, causing tens of thousands of deaths every year.

6 Sep 2017

STING signaling pathway induces apoptosis in T cells

EPFL scientists show that the STING signaling pathway, which helps coordinate the innate immune system, causes cell death in T cells of the adaptive immune system. This “killing” effect includes cancerous T cells, and has implications for treating T cell-derived cancers.

5 Sep 2017

Antibiotics may kill bacteria differently in vitro vs in vivo

Understanding exactly how antibiotics work (or don’t work) is crucial for developing alternative treatment strategies, not only to target new “superbugs,” but also to make existing drugs more effective against their targets.

5 Sep 2017

Research paves way for new drugs that may prevent tumor repopulation after radiation therapy

Whenever an organism is damaged, the cells surrounding the wound receive signals to proliferate more intensely so as to regenerate the injured tissue.

26 Aug 2017

Research reveals underlying reason for intense pain in patients with shingles

Chickenpox is a typical childhood illness. In most cases, it is benign, and the symptoms disappear within ten days. However, its causative agent, Varicella zoster virus (VZV), remains in the organism forever. In some cases, the virus can be reactivated years later, causing a different disease known as herpes zoster, or shingles.

24 Aug 2017

Researchers develop proof-of-concept nanosystem to enhance visualization of tumors

Researchers at Sanford Burnham Prebys Medical Discovery Institute have developed a proof-of-concept nanosystem that dramatically improves the visualization of tumors.

24 Aug 2017

Novel nanolaser can serve as super-bright probe to detect and kill metastasized cancer cells

A nanolaser known as the spaser can serve as a super-bright, water-soluble, biocompatible probe capable of finding metastasized cancer cells in the bloodstream and then killing these cells, according to a new research study.

22 Aug 2017

Researchers discover potential way to trigger regeneration, repair of damaged heart cells

New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases.

21 Aug 2017

New technique quickly, economically monitors multiple molecular interactions in living tissues

A new approach to optical imaging makes it possible to quickly and economically monitor multiple molecular interactions in a large area of living tissue -- such as an organ or a small animal; technology that could have applications in medical diagnosis, guided surgery, or pre-clinical drug testing.

18 Aug 2017

Preclinical research using 1 Tesla desktop MRI

An interview with Dr. Ichio Aoki, National Institutes for Quantum and Radiological Science and Technology.

From Bruker BioSpin - NMR, EPR and Imaging 17 Aug 2017

Scientists discover novel therapeutic strategy to treat aggressive subgroup of lung cancer

Research conducted by a team of Norton Thoracic Institute scientists on a novel therapeutic avenue for an aggressive and difficult to treat subgroup of lung cancer was published in the August 15, 2017 issue of Cancer Research.

17 Aug 2017

BMG LABTECH develop world's first gas ramping function to mimic in vitro ischaemia/reperfusion conditions in a microplate reader

BMG LABTECH developed a new gas ramping function that can fully manipulate the environment within a microplate reader, by mimicking in vitro hypoxia and ischaemia/reperfusion.

From BMG LABTECH GmbH 16 Aug 2017

UAB researchers create small molecule that prevents tooth cavities in preclinical model

University of Alabama at Birmingham researchers have created a small molecule that prevents or impedes tooth cavities in a preclinical model.

10 Aug 2017

Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Supplementing the diet with vitamin B3 during pregnancy may treat the molecular deficiencies in women that can lead to birth defects, according to a landmark study in Australia. Over the last 12 years, developmental geneticist Sally Dunwoodie (Victor Chang Cardiac Research Institute, Sydney) and team have been studying the genes that influence fetal heart and bone development.