The TissueFab® bioink Bone, UV/365nm is designed to enhance the osteogenic differentiation of stem cells. It is made up of a Gelatin methacryloyl (GelMA) and Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate, and it bears a close chemical resemblance to the mineralized phase of bone.
This similarity contributes to its excellent biocompatibility and its osteoinductive and osteoconductive properties, making it highly advantageous for bone regeneration.
HAp-containing hydrogels have been extensively studied in literature, highlighting their compatibility with various additive manufacturing approaches. Bioprinting cell-laden structures using HAp-containing bioink formulations has demonstrated superior osteogenic properties, making this bioink a promising choice for bone tissue regeneration.
Image Credit: Merck
Properties
Source: Merck
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| Description |
0.2 μm sterile filtered, Suitable for 3D bioprinting applications |
| Quality Level |
100 |
| Form |
Gel form (viscous) |
| Impurities |
≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic) |
| Color |
White |
| pH |
6.5-7.5 |
| Application(s) |
3D bioprinting |
| Storage temp. |
2-8 °C |