TissueFab® GelMA-Vis-LAP bioink is a gelatin methacryloyl (GelMA)-based bioink designed for 3D bioprinting applications.
In this process, LAP is employed as the photoinitiator, facilitating blue light photocrosslinking in the printed structure. This formulation has also been optimized to achieve both high printing fidelity and enhanced cell viability. Furthermore, the product's endotoxin levels are notably low, maintained under 50 EU/mL.
Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material originating from natural extracellular matrix (ECM) components. Gelatin's widespread availability, cost-effectiveness, and retention of natural cell binding motifs contribute to its prominence in tissue engineering applications.
Image Credit: Merck
The incorporation of photocrosslinkable methacrylamide functional groups within GelMA enables the synthesis of hydrogels that are both biocompatible and biodegradable. These hydrogels, stable under biologically relevant conditions, foster cell adhesion, spreading, and proliferation while remaining non-immunogenic.
Properties
Source: Merck
| . |
. |
| Quality Level |
100 |
| Description |
Suitable for 3D bioprinting applications with LAP photoinitiator |
| Sterility |
Sterile-filtered |
| Form |
Viscous liquid |
| Impurities |
≤5 CFU/g Bioburden (Fungal)
≤5 CFU/g Bioburden (Total Aerobic)
<50 EU/mL Endotoxin |
| Color |
Colorless to pale yellow |
| Particle size |
0.2 μm |
| pH |
6.5-7.5 |
| Application (s) |
3D bioprinting |
| Storage temp. |
2-8 °C |