TissueFab® bioink (GelAlg)ma-UV/365 nm is an alginate methacrylate based bioink for 3D bioprinting applications. The formulation is optimized for 3D bioprinting of tissues and constructs using extrusion based 3D bioprinters, and can be can be used to bioprint cell-laden hydrogels in desired shape without any supporting material. The crosslinking of printed structures can be done in one step using UV light for further culture and maturation of cells for tissue engineering and regenerative medicine applications.
This bioink is derived from natural polymers − alginate and gelatin. Alginate also known as sodium alginate or alginic acid, is a natural biopolymer obtained from brown algae. Alginate is a natural polysaccharide widely used in tissue engineering. Gelatin contains bioactive peptide sequences similar to native extracellular matrix which promotes integrin mediated cell adhesion and MMP sensitive enzymatic degradation which are essential for cellular functions such as migration, proliferation and differentiation.
Image Credit: Merck
Properties
Source: Merck
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| Quality Level |
100 |
| Description |
Suitable for 3D bioprinting applications |
| Sterility |
Sterile; sterile-filtered |
| Form |
Viscous liquid (or gel) |
| Impurities |
≤5 CFU/g Bioburden |
| Color |
Colorless to pale yellow |
| Particle size |
0.2 μm |
| pH |
6.5-7.5 |
| Application(s) |
3D bioprinting |
| Storage temp. |
2-8 °C |
Features and benefits
- Ready-to-use formulation optimized for high printing fidelity and cell viability, eliminating the lengthy bioink formulation development process
- Step-by-step protocols developed and tested by MilliporeSigma 3D Bioprinting Scientists, no prior 3D bioprinting experience needed
- Suitable for different extrusion-based 3D bioprinter model
Packaging
10 mL in a glass bottle