Biochemistry

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New link between two important products of nitric oxide discovered

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.

4 Oct 2019

Exploiting the weak spot in pathogenic bacteria to develop new antibiotics

Antibiotics are still the most important weapon for combatting bacterial infections. But medical science is running out of "ammunition" because of more and more frequently occurring resistances.

4 Oct 2019

Chemical-sensing cells in the gums protect the mouth from infections

Newly discovered chemical-sensing cells in the gums protect the mouth by standing guard against infections that damage soft tissue and destroy the bone that supports the teeth, report researchers from the Monell Chemical Senses Center in an animal study published this week in Nature Communications.

3 Oct 2019

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women.

3 Oct 2019

High-fat diet with high fructose damages mitochondria in the liver, study shows

Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver's ability to properly metabolize fat.

1 Oct 2019

Chemicals used for pharmaceuticals could be made more sustainably by new catalysts

High value chemicals used to make pharmaceuticals could be made much cheaper and quicker thanks to a series of new catalysts made by scientists at the University of Warwick in collaboration with GoldenKeys High-Tech Co., Ltd. in China.

1 Oct 2019

UK-based scientists aim to make infant formula more like human breast milk

UK-based scientists have engineered plants to produce an oil that mimics the chemical structure of human milk fat, a major component of breast milk.

1 Oct 2019

Driving Adoption of Digital Pathology with Image Search

Driving adoption of digital pathology through the Scan Image Search from Huron Digital Pathology. Patrick Myles talks to the Dell Healthcare PowerChat Podcast.

From Huron Digital Pathology 1 Oct 2019

Lipid produced in response to cold helps reduce blood sugar

Researchers based in Brazil, the United States and Germany have discovered that 12-HEPE, a lipid produced in response to cold by brown adipose tissue in the human body, helps reduce blood sugar. The results of their experiments with mice pave the way for new treatments for diabetes.

27 Sep 2019

Rice chemist explores how extra amino acid could be used to make life-saving substances

There are 20 amino acids in the standard genetic code. A Rice University professor wants to know what one can do with 21.

27 Sep 2019

Study may help scientists to learn more about the causes of chronic pain

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal - but not physical- sensations in mice.

27 Sep 2019

Russian researchers come up with faster method to discover antibiotics

Russian biochemists have identified a promising new class of antibiotics. Having studied over 125,000 molecules, they found that 2-pyrazol-1-yl-thiazole derivatives exhibit antibacterial properties.

26 Sep 2019

Monitoring the Human Proteome using diaPASEF

In this interview, Dr. Hannes Röst describes how his lab are using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

From Bruker Life Sciences Mass Spectrometry 25 Sep 2019

TUM researchers reveal how chaperones detect immature immune signaling proteins

The cells of our immune system constantly communicate with one another by exchanging complex protein molecules.

24 Sep 2019

Researchers map and activate bacterial 'immune defense system'

With the aid of highly advanced microscopes and synchrotron sources, researchers from the University of Copenhagen have gained seminal insight into how bacteria function as defense mechanisms against attacks from other bacteria and viruses.

24 Sep 2019

Non-viral gene delivery method more effective and safer than standard viral approaches

The non-viral, bio-inspired gene delivery method developed by researchers at RMIT University has proven effective in laboratory tests and is safer than standard viral approaches.

24 Sep 2019

Study uncovers epigenetic origins for hypersexual disorder

A new study has shown that epigenetic changes lead to overactivity of the hormone oxytocin, and this is a key element in hypersexual disorder.

24 Sep 2019

Using 'Trojan horse' strategy to kill deadly antibiotic-resistant pathogens

Pseudomonas aeruginosa is a dangerous bacterium that causes infections in hospital settings and in people with weakened immune systems.

24 Sep 2019

Discovery provides potential therapeutic target for prostate cancers with PTEN mutation

PTEN, a tumor suppressor gene mutated in approximately 20% of primary prostate cancers, and in as many as 50% of androgen deprivation-resistant prostate cancers, relies on another gene, ARID4B, to function.

24 Sep 2019

Fullerene compounds effectively combat dangerous viral infections

Scientists from the Skoltech Center for Energy Science and Technology and the Institute of Problems of Chemical Physics of RAS in collaboration with researchers from four other Russian and foreign research centers have discovered a new reaction that helps obtain water-soluble fullerene derivatives which effectively combat flu viruses, human immunodeficiency virus, herpes simplex virus, and cytomegalovirus.

23 Sep 2019