Biochemistry

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New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Discovery provides better understanding of retinal protein's structure and function

Scientists have discovered a mechanism by which an area of a protein shape-shifts to convert vitamin A into a form usable by the eye's light-sensing photoreceptor cells.

26 Oct 2022

Discovery of small molecule enzyme inhibitor could be the key to treating cancers, autoimmune diseases

Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases.

25 Oct 2022

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

Scientists have shown that they can detect SARS-CoV-2, the virus that causes COVID-19, in the air by using a nanotechnology-packed bubble that spills its chemical contents like a broken piñata when encountering the virus.

25 Oct 2022

TANGO2 plays a role in heme homeostasis, research reveals

Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with defects in heme homeostasis.

21 Oct 2022

New technology could dramatically speed up antibiotic resistance testing

Significant time is needed to determine the drug susceptibility profile of a bacterial infection. Now, researchers from Nara Institute of Science and Technology and collaborating partners have published reports on a technology that will dramatically speed up this otherwise slow process and possibly help save lives.

21 Oct 2022

SARS-CoV-2 virus alters the composition of breast milk, research shows

A research team from the University of Huelva in collaboration with the MilkCORONA initiative has demonstrated that the SARS-CoV-2 virus alters the composition of breast milk.

19 Oct 2022

Rare insect-eating mushrooms show potential to develop new anti-viral and cancer medications

Scientists studying the medicinal potential of a rare insect-eating mushroom have found a way to grow the elusive fungi in the lab, opening the way for the development of new anti-viral and cancer medications.

19 Oct 2022

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

A vaccine design approach that could protect against new variants of SARS-CoV-2, the virus that causes COVID-19, but also potentially protects against other coronaviruses is one step closer to reality as a result of Penn State College of Medicine research.

18 Oct 2022

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars.

18 Oct 2022

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

Revealing zinc's interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.

17 Oct 2022

New tissue clearing method simplifies and speeds up the process to make organs transparent for imaging

The adage 'Seeing is believing' was front of mind for Dr. Chih-Wei Logan Hsu and Dr. Joshua D. Wythe at Baylor College of Medicine as they and their colleagues developed an innovative technology called EZ Clear.

13 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes - or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

High-sugar diet lowers the ability of the taste system to sense sweetness

For many people, a high-sugar diet has become almost accidental. Three-quarters of food in the supermarket has added sugar, according to University of Michigan researcher Monica Dus, leading the scientist to wonder whether our sense of taste can become dulled to sweetness.

12 Oct 2022

Biochemistry

New discovery may change the textbook model of GPCR-mediated signaling

Discovery provides better understanding of retinal protein's structure and function

Discovery of small molecule enzyme inhibitor could be the key to treating cancers, autoimmune diseases

Using a nanotechnology-packed bubble to detect SARS-CoV-2 virus

TANGO2 plays a role in heme homeostasis, research reveals

New technology could dramatically speed up antibiotic resistance testing

SARS-CoV-2 virus alters the composition of breast milk, research shows

Rare insect-eating mushrooms show potential to develop new anti-viral and cancer medications

Adaptation-proof SARS-CoV-2 vaccine design is one step closer to reality

New machine learning model can screen novel drug compounds to accurately predict efficacy in humans

KAUST study reveals unexpected role for zinc in the prevention of Parkinson's disease

New tissue clearing method simplifies and speeds up the process to make organs transparent for imaging

Metabolite discovery offers a potential way to address metabolic conditions

High-sugar diet lowers the ability of the taste system to sense sweetness

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Protoporphyrin IX delayed fluorescence imaging as a modality for hypoxia-based oncologic surgical guidance

Scientists discover a promising strategy for development of broad-spectrum antiviral therapies

Virginia Tech researchers examine how sleep deprivation may affect mosquito’s ability to spread disease

Stanford researchers create new technique for controlling protein production

Researchers uncover an intriguing previously unknown ability of Swiss army knife enzyme

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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