Cell Biology

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Study reveals the genetic cause of congenital malformation

Study by the University of Bonn reveals that genetic information controls development of the urinary tract, rectum and genitals Spontaneous mutations of a single gene are likely to cause serious developmental disorders of the excretory organs and genitalia.

7 Aug 2020

Study: Early training of cell development and network improves response

When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.

7 Aug 2020

Researchers investigate the survivability of E. coli bacteria based on fast or slow growth

Bacteria are survival artists: When they get nutrition, they multiply rapidly, albeit they can also survive periods of hunger.

7 Aug 2020

Immune system derails during severe course of COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

6 Aug 2020

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

A team of researchers from New Jersey Institute of Technology and Children's Hospital of Philadelphia have developed an algorithm through machine learning that helps predict sites of DNA methylation - a process that can change the activity of DNA without changing its overall structure - and could identify disease-causing mechanisms that would otherwise be missed by conventional screening methods.

6 Aug 2020

An 'intelligent' strategy for real-time evaluation of photothermal therapy efficiency on tumors

Photothermal therapy (PTT) is a promising alternative method for cancer treatment due to advantages of non-invasiveness, precise temporal and spatial control, strong specificity and high tumor destruction efficiency.

6 Aug 2020

A new device for modeling the human gut’s complex microbiome environment

Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health.

6 Aug 2020

SARS-CoV-2 may not be targeting taste bud cells

An intriguing early symptom among some COVID-19 patients is the loss of the sense of smell and/or taste, which has led to the suspicion that the virus that causes the illness, SARS-CoV-2, could be targeting taste buds.

5 Aug 2020

Beneficial microbes reprogram the B cell repertoire that produce antibodies

The mammalian gut is home to trillions of microbes which are essential for a healthy immune system and good nutrition.

5 Aug 2020

Discovery of enzyme could provide new route for treating Huntington's disease

Scientists at EPFL's Brain Mind Institute have identified an enzyme that can play a central role in developing a new route of treatment for Huntington's Disease.

5 Aug 2020

Study shows the strategies tumor cells use to evade immune defense

Scientists are increasingly trying to use the body's own immune system to fight cancer. A new study by the University of Bonn and research institutions in Australia and Switzerland now shows the strategies tumor cells use to evade this attack.

5 Aug 2020

Researchers identify novel protein that reduces adverse effect of hypertonicity

A University of Houston College of Medicine researcher has found how a protein inside the body reduces the adverse effects of hypertonicity, an imbalance of water and solutes inside cells. Hypertonicity causes cell shrinkage and eventual cell death.

5 Aug 2020

Study: "Memory" T cells that recognize common cold coronaviruses also recognize SARS-CoV-2

Your immune system's "memory" T cells keep track of the viruses they have seen before. This immune cell memory gives the cells a headstart in recognizing and fighting off repeat invaders.

5 Aug 2020

Biomedical engineers create artificial organelles to control biological function in cells

Biomedical engineers at Duke University have demonstrated a method for controlling the phase separation of an emerging class of proteins to create artificial membrane-less organelles within human cells.

4 Aug 2020

UC Riverside joins ATP-Bio to preserve a wide range of biological systems

The National Science Foundation, or NSF, announced today that it has awarded a $26 million Engineering Research Center grant to the University of Minnesota and Massachusetts General Hospital, in collaboration with UC Riverside and UC Berkeley.

4 Aug 2020

Decoy receptor neutralizes SARS-CoV-2 virus in tissue cultures

As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they're exposed. A new study suggests luring the virus with a decoy - an engineered, free-floating receptor protein - binds the virus and blocks infection.

4 Aug 2020

New method reveals the dynamics of cell development and gene activity

Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only rather than time-lapse films.

4 Aug 2020

Chlamydiae need a lot of glutamine to multiply in human cells

If chlamydiae want to multiply in a human cell, the first thing they need is a lot of glutamine. Würzburg researchers have clarified how the pathogenic bacteria obtain this substance.

3 Aug 2020

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron.

3 Aug 2020

High-speed atomic force microscopy reveals diverse amyloid structures and dynamics

In the human body, proteins sometimes occur in fibrillar aggregates called amyloids. Although certain amyloids are known to have a biological function, amyloid formation is often associated with pathologies, including Alzheimer's and Parkinson's diseases.

3 Aug 2020