Cell Biology

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Hairy human skin grown from pluripotent stem cells

Building on years of groundbreaking discoveries in stem cell research, scientists from Indiana University School of Medicine and Harvard Medical School have determined how to grow hairy skin using human stem cells--developing one of the most complex skin models in the world.

4 Jun 2020

Researchers decipher deadly bacterial infection in pigs

The Clostridium perfringens bacterium is part of the large Clostridium genus which can cause various fatal illnesses in animals and humans.

4 Jun 2020

Small protein has a large impact on bacterial gene regulation

Meningococci are bacteria that can cause life-threatening meningitis and sepsis. These pathogens use a small protein with a large impact: The RNA-binding protein ProQ is involved in the activation of more than 250 bacterial genes.

4 Jun 2020

Diet and gut microbiome affect outcomes of chemotherapy

What we eat can affect the outcome of chemotherapy – and likely many other medical treatments – because of ripple effects that begin in our gut, new research from the University of Virginia suggests.

4 Jun 2020

Hesperos’ immune system-on-a-chip emulates immune reactions for tissue damage and acute inflammation

Hesperos Inc., pioneers of the Human-on-a-Chip in vitro system, today announced the publication of a new peer-reviewed publication that describes how the company’s technology can be used to investigate immune responses following treatment with biological therapeutics for multi-organ systemic diseases, including cancer, infectious diseases and inflammatory disorders.

4 Jun 2020

Using advanced microscopy techniques to see single molecules of telomerase in living cells

Canadian scientists have achieved a first in the study of telomerase, an essential enzyme implicated in aging and cancer.

3 Jun 2020

Scientists uncover why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

3 Jun 2020

Study sheds new light on how respiratory virus breaks into cells to cause infection

New research from University of Alberta microbiologists has shed new light on how the respiratory syncytial virus (RSV)--one of the most common viral infections--breaks into our cells to cause infection.

3 Jun 2020

Artificial red blood cells mimic the favorable properties of natural ones

Scientists have tried to develop synthetic red blood cells that mimic the favorable properties of natural ones, such as flexibility, oxygen transport and long circulation times.

3 Jun 2020

‘Terminator’ protein suppresses tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

3 Jun 2020

Bacteria lurking in cancer cells may affect treatment

Cancer cells are comfy havens for bacteria. That conclusion arises from a rigorous study of over 1,000 tumor samples of different human cancers.

2 Jun 2020

Explosion of immune cells in mouse lungs after birth may help protect against infections

An explosion in the number and types of immune cells in the lungs of newborn mice likely helps them adapt to breathing and protects them from infection, says a new study published today in eLife.

2 Jun 2020

Researchers successfully transplant fully functional mini livers into rats

Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats.

2 Jun 2020

ISSCR 2020 Virtual Meeting to deliver comprehensive scientific education program

The International Society for Stem Cell Research has transformed its annual scientific meeting into a virtual experience, bringing the global stem cell community together to share knowledge, collaborate, and network.

2 Jun 2020

Study resolves contradictions surrounding p53 gene's role in pluripotent stem cell differentiation

The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor gene."

1 Jun 2020

Stem cell model sheds new light on the devastating process of neurodegeneration

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

1 Jun 2020