Cell Biology

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Study shows how mast cells regulate calcium levels to control the immune response

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium levels to keep the immune response under control.

23 Jul 2020

Calcium channel subunits play a crucial role in neurological disorders

The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells.

22 Jul 2020

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed to act as a gatekeeper for sensory information flowing to the cortex.

22 Jul 2020

Researchers discover how infectious bacteria can produce genetic variants among siblings

A research team from the University of Tübingen and the German Center for Infection Research is investigating how pathogens influence the immune response of their host with genetic variation.

22 Jul 2020

Erectile dysfunction drugs lower the accumulation of toxic proteins in zebrafish models

The aberrant buildup of misfolded proteins is a hallmark of a host of disorders, including neurodegenerative diseases such as Alzheimer's and Parkinson's.

22 Jul 2020

Study points to an important role for white blood cells in brain development

Whether white blood cells can be found in the brain has been controversial, and what they might be doing used to be complete mystery.

22 Jul 2020

Researchers demonstrate the production of viral parts within artificial cells

Scientists searching for better diagnostic tests, drugs or vaccines against a virus must all begin by deciphering the structure of that virus.

21 Jul 2020

Proximity of mutated cells guides the initiation of tumor

Scientists have revealed a key factor that influences whether malignant cells will grow to form a tumor, in a new study published today in eLife.

21 Jul 2020

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Age shows nowhere better than on the skin. The ravages of time on skin and the epidermal stem cells that differentiate to replenish its outer layer have been hypothesized, but there has been no method to evaluate their aging at the molecular level.

21 Jul 2020

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

21 Jul 2020

Researchers visualize DNA G-quadruplex formation in live cells for the first time

The formation of four-stranded DNA has been tracked in living human cells, allowing scientists to see how it works, and its possible role in cancer.

20 Jul 2020

Harvard scientists uncover the real reason behind goosebumps

If you've ever wondered why we get goosebumps, you're in good company -- so did Charles Darwin, who mused about them in his writings on evolution.

20 Jul 2020

Using AI to pinpoint neurons involved in gait reacquisition

Researchers at EPFL are able to get paralyzed rodents walking again by stimulating the animals' damaged spinal cords.

20 Jul 2020

McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

Mutant zebrafish opens a window into evolutionary history of human spine

A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Study reveals intricate details about the biology of huntingtin protein

A new study reveals intricate details about the biology of the huntingtin protein (HTT), which is responsible for Huntington's disease.

17 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Researchers unravel key mechanisms behind the mysteries of aging

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

16 Jul 2020

Blood vessels communicate with sensory neurons to regulate their proliferation

Researchers at Pompeu Fabra University have shown for the first time that blood vessels communicate with neurons in the peripheral nervous system, regulating their proliferation and differentiation.

16 Jul 2020

Cell Biology

Study shows how mast cells regulate calcium levels to control the immune response

Calcium channel subunits play a crucial role in neurological disorders

Neuroscientists map brain's sensory gatekeeper in unprecedented detail

Researchers discover how infectious bacteria can produce genetic variants among siblings

Erectile dysfunction drugs lower the accumulation of toxic proteins in zebrafish models

Study points to an important role for white blood cells in brain development

Researchers demonstrate the production of viral parts within artificial cells

Proximity of mutated cells guides the initiation of tumor

Glycome shift in epidermal stem cells could serve as potential biomarker of aging

Chronic inflammation associated with IBD disrupts tissue structure of the colon, study finds

Researchers visualize DNA G-quadruplex formation in live cells for the first time

Harvard scientists uncover the real reason behind goosebumps

Using AI to pinpoint neurons involved in gait reacquisition

McGill researchers discover bacterial organelles involved in gene expression

Mutant zebrafish opens a window into evolutionary history of human spine

How immune cells switch to attack mode

Study reveals intricate details about the biology of huntingtin protein

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Researchers unravel key mechanisms behind the mysteries of aging

Blood vessels communicate with sensory neurons to regulate their proliferation

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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