Cell Biology

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Study shows how plants operate on a molecular level

New research from the University of Virginia School of Medicine reveals how plants create the load-bearing structures that let them grow - much like how building crews frame a house.

10 Jul 2020

Study sheds new light on neurobiological processes that control drug-related adaptations

The lab of Jeremy Day, Ph.D., at the University of Alabama at Birmingham, has used single-nucleus RNA sequencing approaches to compare transcriptional responses to acute cocaine in 16 unique cell populations from a portion of the brain called the nucleus accumbens, or NAc.

10 Jul 2020

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Activating the immune system of the body is a promising form of treatment for cancer. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient groups which could potentially benefit from immunotherapies.

9 Jul 2020

Overzealous guardians in the cells could increase cancer risk

Researchers at the UiO and OUS have discovered how destructive changes occur in our genome. This could lead to cancer. Their results have been published in the journal Nature Cell Biology.

9 Jul 2020

Bats offer clues to combat COVID-19

Bats are often considered patient zero for many deadly viruses affecting humans, including Ebola, rabies, and, most recently, the SARS-CoV-2 strain of virus that causes coronavirus.

9 Jul 2020

Scientists introduce a new approach for immunological tumor treatment

Our immune system ought to be able to recognize and kill tumor cells. However, many tumors deceive the immune system.

8 Jul 2020

Novel mechanism regulates planar cell polarity crucial for organ function

Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function.

8 Jul 2020

RNA plays key role in helping stem cells know what to become

Look deep inside our cells, and you'll find that each has an identical genome -a complete set of genes that provides the instructions for our cells' form and function.

7 Jul 2020

Study of lysosomal function during mitosis reveals new biomarker for chromosomal instability

A team from the Bellvitge Biomedical Research Institute and the University of Barcelona, in collaboration with a researcher from the Mayo Clinic and the University of Minnesota, have described that lysosomes and autophagy processes are active during mitosis and are necessary for a correct cell division.

7 Jul 2020

Scientists engineer natural killer cells that target tumors and their immunosuppressive allies

Scientists have engineered natural killer immune cells that not only kill head and neck tumor cells in mice but also reduce the immune-suppressing myeloid cells that allow tumors to evade the immune response, according to a new study in eLife.

7 Jul 2020

New discovery helps explain heart defects in Barth syndrome

The heart needs energy to pump blood. So, energy production defects in heart muscles result in a variety of cardiac diseases.

7 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

Gene coding regions constitute 2% of the human genome. St. Jude Children's Research Hospital scientists have developed a computational tool to identify alterations that drive tumor formation in the remaining 98% of the genome.

6 Jul 2020

BU researchers develop new method to better understand cell communication

Researchers from Boston University School of Medicine have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

6 Jul 2020

Real-time tracking of protein filaments in the nuclear pore complex

In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing solution in the inside of a cell).

6 Jul 2020

New assay uses unique fluorescent tags to analyze multiple cell populations

An efficient, robust method of examining the interactions between cells uses fluorescent tagging to simultaneously analyze multiple cell populations, speeding up a once tedious and limiting process.

6 Jul 2020

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack.

6 Jul 2020

New strategies can help increase the efficiency of artificial cell reprogramming

Maria-Elena: Can you imagine being able to artificially generate cells that can develop into any cell type? That would be really fantastic! We call this ability 'totipotency' and it is the highest level of cellular plasticity.

6 Jul 2020

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

Toxic metallic air pollution nanoparticles are getting inside the crucial, energy-producing structures within the hearts of people living in polluted cities, causing cardiac stress - a new study confirms.

3 Jul 2020

New formula more accurately compares the ages of humans and dogs

If there's one myth that has persisted through the years without much evidence, it's this: multiply your dog's age by seven to calculate how old they are in "human years." In other words, the old adage says, a four-year-old dog is similar in physiological age to a 28-year-old person.

2 Jul 2020

Cell Biology

Study shows how plants operate on a molecular level

Study sheds new light on neurobiological processes that control drug-related adaptations

Mapping immune landscape of hematological malignancies may help improve cancer therapies

Overzealous guardians in the cells could increase cancer risk

Bats offer clues to combat COVID-19

Scientists introduce a new approach for immunological tumor treatment

Novel mechanism regulates planar cell polarity crucial for organ function

RNA plays key role in helping stem cells know what to become

Study of lysosomal function during mitosis reveals new biomarker for chromosomal instability

Scientists engineer natural killer cells that target tumors and their immunosuppressive allies

New discovery helps explain heart defects in Barth syndrome

DNA resection pathways are highly specific, shows study

Researchers create new tool to identify cancer-causing mutations lurking in 98% of the genome

BU researchers develop new method to better understand cell communication

Real-time tracking of protein filaments in the nuclear pore complex

New assay uses unique fluorescent tags to analyze multiple cell populations

Study reveals key role of a protein in regulating scar tissue growth after heart attacks

New strategies can help increase the efficiency of artificial cell reprogramming

Toxic metallic air pollution nanoparticles found inside myocardial mitochondria of city dwellers

New formula more accurately compares the ages of humans and dogs

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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