Cell Biology

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New technique enables the study of transporter proteins at a single-molecule level

Like a boat helping passengers cross a river, transporters move substances across cell membranes. This process is fundamental to the healthy functioning of cells in life forms from bacteria to humans.

14 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

Leukemia type B cell can transform into a macrophage through epigenetic changes

All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects.

13 Nov 2019

Crick study reveals vital protective role of telomere t-loops

Loops at the ends of telomeres play a vital protective role preventing irretrievable damage to chromosomes, according to new research from the Crick.

From The Francis Crick Institute 12 Nov 2019

White blood cells control final moments of their death

La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body.

12 Nov 2019

New AI-driven approach for single blood cell classification

For the first time, researchers from Helmholtz Zentrum München and the University Hospital of LMU Munich show that deep learning algorithms perform similar to human experts when classifying blood samples from patients suffering from acute myeloid leukemia.

12 Nov 2019

Scientists publish structural and functional keys that distinguish two similar transcription factors

Scientists at the Institute for Research in Biomedicine, in collaboration with the Sloan Kettering Institute (New York, US), have published the structural and functional keys that distinguish two very similar transcription factors, namely SMAD2 and SMAD3.

12 Nov 2019

Researchers condemn Trump administration’s human fetal tissue ban

After more than 30 years of researchers using human fetal tissue to investigate causes of disease and the body’s response to medications, the Trump administration banned this type of research on June 5, 2019.

11 Nov 2019

Musical pleasure linked to right combination of uncertainty and surprise

Why is it that people find songs such as James Taylor's "Country Roads," UB40's "Red, Red Wine," or The Beatles' "Ob-La-Di, Ob-La-Da" so irresistibly enjoyable? In a study reported in the journal Current Biology on November 7, researchers analyze 80,000 chords in 745 classic U.S. Billboard pop songs--including those three--and find that musical pleasure comes from the right combination of uncertainty and surprise.

8 Nov 2019

Human heart cells show remarkable adaptability during and after spaceflight

Heart muscle cells derived from stem cells show remarkable adaptability to their environment during and after spaceflight, according to a study publishing November 7 in the journal Stem Cell Reports.

8 Nov 2019

Understanding Monoclonal Antibody Unfolding and Aggregation

A therapeutic monoclonal antibody and its Fab and Fc fragments were recently investigated using differential scanning fluorimetry, temperature-ramped dynamic light scattering, and turbidity measurements.

From Waters | Wyatt Technology 8 Nov 2019

Sartorius publishes third edition of the Live-Cell Analysis Handbook

Sartorius is excited to announce publication of the third edition of our Live-Cell Analysis Handbook, a popular publication for a broad range of scientists who perform cell biology assays as part of their research.

From Sartorius 8 Nov 2019

Researchers use transplanted stem cells to grow fully functional lungs in mouse embryos

Researchers at Columbia University were able to grow fully functional lungs in mouse embryos using transplanted stem cells. The findings suggest that it may be ultimately possible to use the technique to grow human lungs in animals for patients who need transplants and to study new lung treatments.

7 Nov 2019

Integrating European life sciences in the area of imaging

The European Commission has officially established Euro-BioImaging - which provides life scientists with open access to a broad range of technologies and resources in biological and biomedical imaging - as a European Research Infrastructure Consortium.

7 Nov 2019

Study uncovers how cells 'forget their past' while developing into a specific cell

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’.

7 Nov 2019

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

Sphere Fluidics and Peak Analysis and Automation, announce optimization of the Single Cell Analysis System through integration with automated plate handler.

From Sphere Fluidics 7 Nov 2019

Cytoplasm of ruptured Xenopus frog eggs reorganizes into cell-like compartments, study shows

Can scrambled eggs unscramble themselves? Well, sort of.

6 Nov 2019

Scientists discover structure of novel RNA-modifying enzyme

RNA, or ribonucleic acid, is present in the cells of all living beings and required to synthesize proteins. A research team at the University of California, Riverside, has discovered the structure of a novel RNA-modifying enzyme, ZCCHC4, and identified the mechanism that controls how this enzyme recognizes its substrate.

6 Nov 2019

Tumor cell plasticity counts during cancer metastasis

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality.

5 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019