Cell Biology

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Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

CNRS researchers at the Institut Curie have recently shown that cancer cells use a membrane protein that has been known for several decades to internalise iron.

3 Aug 2020

High-speed atomic force microscopy reveals diverse amyloid structures and dynamics

In the human body, proteins sometimes occur in fibrillar aggregates called amyloids. Although certain amyloids are known to have a biological function, amyloid formation is often associated with pathologies, including Alzheimer's and Parkinson's diseases.

3 Aug 2020

New method to detect rare circulating tumor cells in blood samples

Metastasis - the development of tumor growth at a secondary site - is responsible for the majority of cancer-related deaths. It occurs when the primary tumor site sheds cancerous cells which are then circulated through the body via blood vessels or lymph nodes.

3 Aug 2020

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Scientists led by Javier Martinez from the Max Perutz Labs, a joint venture of the Medical University of Vienna and the University of Vienna, have identified a unique chemical reaction at the end of RNA molecules for the first time in human cells.

31 Jul 2020

Multiple, intertwined cell death systems to prevent the spread of 'intracellular' bacteria

Melbourne researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the 'intracellular' bacterium Salmonella, an important cause of typhoid fever which kills more than 100,000 people annually.

30 Jul 2020

Immunosuppressive steroids help tumors to evade the immune system

A new study has revealed that tumors can evade the immune system by telling immune cells to produce immunosuppressive steroids.

30 Jul 2020

Mice born with Fragile X syndrome have fewer cell antennas

Structures called primary cilia - which act like TV antennas for cells to detect signals - are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science Center at San Antonio.

30 Jul 2020

Researchers use human genome database to study cancer cells

Florida State University Professor of Biological Science David Gilbert is using the latest information about the human genome as a guide to better understand cancer.

30 Jul 2020

Study finds fungal isolates with high levels of virulence in different hospitals

A group of researchers from Brazil, Denmark, Italy and Spain analyzed 884 samples of fungi of the genus Candida collected from 16 hospitals and found a significant number of clusters in more than one hospital.

29 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Study reveals mechanisms of mechanical stretch induced skin expansion

The capacity of the skin to expand by mechanical stretching has been used for decades in plastic and reconstructive surgery to generate an excess of skin that can be used to repair birth defects, damaged tissues, and breast reconstruction after mastectomy.

29 Jul 2020

Research may provide new insights into wound healing

When we get a wound on our skin, the cells in our bodies quickly mobilize to repair it. While it has been known how cells heal wounds and how scars form, a team led by researchers from Washington University in St. Louis has determined for the first time how the process begins, which may provide new insight into wound healing, fibrosis and cancer metastasis.

29 Jul 2020

Study reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

28 Jul 2020

'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

UMass Amherst biologists identify environmental sensing mechanism in cells

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

28 Jul 2020

Cell Biology

Membrane protein regulates epigenetic plasticity by mediating iron endocytosis

High-speed atomic force microscopy reveals diverse amyloid structures and dynamics

New method to detect rare circulating tumor cells in blood samples

Study: ANGEL2 enzyme performs unique chemical reaction at the end of RNA molecules

Multiple, intertwined cell death systems to prevent the spread of 'intracellular' bacteria

Immunosuppressive steroids help tumors to evade the immune system

Mice born with Fragile X syndrome have fewer cell antennas

Researchers use human genome database to study cancer cells

Study finds fungal isolates with high levels of virulence in different hospitals

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

Study reveals mechanisms of mechanical stretch induced skin expansion

Research may provide new insights into wound healing

Study reveals multiple characteristics of HIV-1-producing cells in vivo

Deep learning algorithm can identify genetic alterations from routine histological images of tumors

'Synthetic lethality' could be exploited for cancer therapy

Identification of MTK1 SAPKKK as new human oxidative stress sensor

UMass Amherst biologists identify environmental sensing mechanism in cells

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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