Cell Biology

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Antibiotic treatment can cause transient and long-term disruption of gut microbes

Trillions of microbes in the intestine aid human health, including digestion of breast milk, breaking down fiber and helping control the immune system.

22 Oct 2019

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

A new study from Indiana University has revealed a previously unknown role a protein plays in helping bacteria reel in DNA in their environment -- like a fisherman pulling up a catch from the ocean.

21 Oct 2019

Development and assessment of NGS-based microsatellite instability assay

The assay has a clinically relevant five-day turnaround time and can be conducted on as little as 20 ng genomic DNA with a batch size of up to forty samples in a single run.

18 Oct 2019

Researchers discover genes linked to sex ratio and male fertility in mice

One of the more recent trends among parents-to-be is the so-called gender reveal, a party complete with pink or blue cake to answer the burning question, "Is it a boy or girl?" After all, it's presumed that there's a 50-50 chance you'd have one or the other.

18 Oct 2019

Adding plant-based compound to gene therapy could improve treatment outcomes

Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia.

17 Oct 2019

Rare sex-specific brain cells found in male and female mice

Caltech researchers have discovered rare brain cell types that are unique to male mice and other types that are unique to female mice. These sex-specific cells were found in a region of the brain that governs both aggression and mating behaviors.

17 Oct 2019

Research could help explain why memory in old age is less flexible than in young adulthood

New research from King's College London and The Open University could help explain why memory in old age is much less flexible than in young adulthood.

17 Oct 2019

Researchers obtain 3D structural snapshots of key regulator of cell biology

Some of the greatest insights into cancer and how to treat it come when basic scientists and cancer biologists and clinicians collaborate.

17 Oct 2019

Skin's circadian clock is independent of the eyes or brain, study finds

Squids, octopuses, cuttlefish, amphibians, and chameleon lizards are among the animals that can change the color of their skin in a blink of an eye. They have photoreceptors in their skin that operate independently of their brain. The photoreceptors are part of a family of proteins known as opsins.

16 Oct 2019

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study, to be published in PNAS, provides a biophysical model that reveals how damage accumulates in the shapes of cellular proteins with age and is a trigger to death.

16 Oct 2019

Scientists decipher assembly line of glutamate receptors

Rapid communication of neurons in the brain, as well as the ability to learn, fundamentally rely on neurotransmitter receptors located in the contact sites of neurons, the synapses. The most important receptors in the mammalian brain are glutamate receptors of the AMPA-type that generate the electrical signal required for fast communication between neurons.

16 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

The Scientist names Cyto-Mine technology #1 in the Top 10 Innovations of 2018

We are delighted to announce that Cyto-Mine is one of the winners of The Scientist 2018 Top 10 Innovations!

From Sphere Fluidics 16 Oct 2019

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.

15 Oct 2019

Engineered communities of cells make long-distance calls

The search for effective biological tools is a marathon, not a sprint, even when the distances are on the microscale. A discovery at Rice University on how engineered communities of cells communicate is a long step in the right direction.

15 Oct 2019

New technique reveals how the brain responds to light signals received by the retina

In recent decades, scientists have learned a great deal about how different neurons connect and send signals to each other. But it's been difficult to trace the activity of individual nerve fibers known as axons, some of which can extend from the tip of the toe to the head.

15 Oct 2019

Study suggesting that CRISPR babies are likely to die early has been retracted

A research paper that sparked concerns about the lifespan of China's first gene-edited babies has been retracted due to technical errors.

15 Oct 2019

Highly sensitive method can 'track' fat metabolism

Without fat, nothing works in the body: These substances serve as energy suppliers and important building blocks - including for the envelopes of living cells.

14 Oct 2019

Custom-made oligonucleotide therapy for girl with fatal Batten disease

Sufferers of fatal Batten disease have been given new hope as scientists develop a custom-made oligonucleotide therapy for a young girl.

14 Oct 2019

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

The discovery in the 1990s that a mutation in a single gene of an experimental worm could double its lifespan set off a stampede of research on the molecular biology of aging and triggered hopes that drug therapies or other interventions could be developed to extend healthy human lifespan. But as is often the case in science, the genetic regulation of aging is more complicated than it first appeared.

10 Oct 2019

Cell Biology

Antibiotic treatment can cause transient and long-term disruption of gut microbes

Discovery about DNA-reeling bacteria can help inform strategies to stop bacterial infection

Development and assessment of NGS-based microsatellite instability assay

Researchers discover genes linked to sex ratio and male fertility in mice

Adding plant-based compound to gene therapy could improve treatment outcomes

Rare sex-specific brain cells found in male and female mice

Research could help explain why memory in old age is less flexible than in young adulthood

Researchers obtain 3D structural snapshots of key regulator of cell biology

Skin's circadian clock is independent of the eyes or brain, study finds

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Scientists decipher assembly line of glutamate receptors

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

The Scientist names Cyto-Mine technology #1 in the Top 10 Innovations of 2018

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Engineered communities of cells make long-distance calls

New technique reveals how the brain responds to light signals received by the retina

Study suggesting that CRISPR babies are likely to die early has been retracted

Highly sensitive method can 'track' fat metabolism

Custom-made oligonucleotide therapy for girl with fatal Batten disease

Genetic mechanisms could serve as a road map for screening new drugs to prolong healthy lifespan

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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