Cell Biology

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Tumor cell plasticity counts during cancer metastasis

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality.

5 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

New technique uses light to control lifetime of protein inside the cell

Researchers report they have developed a new technique that uses light to control the lifetime of a protein inside the cell. This method will allow scientists to better observe how specific proteins contribute to health, development and disease.

4 Nov 2019

Scientists capture elusive cancer-related protein in action

Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in the cell.

4 Nov 2019

Protein may help predict, prevent and treat brain metastases

A protein that breast, lung and other cancers use to promote their spread--or metastasis--to the brain, has been identified by a team led by Weill Cornell Medicine and New York-Presbyterian investigators. The protein, CEMIP, will now be a focus of efforts to predict, prevent and treat brain metastases, which are a frequent cause of cancer deaths.

4 Nov 2019

Researchers make major breakthrough in cell signalling

Researchers at the University of Liverpool have made a major breakthrough in the field of cell signalling.

4 Nov 2019

RCSB Protein Data Bank at Rutgers receives $34.5 million funding

The RCSB Protein Data Bank headquartered at Rutgers University-New Brunswick has been awarded $34.5 million in grants over five years from three U.S. government agencies.

4 Nov 2019

Researchers develop new way to 3D print living skin with blood vessels

Researchers at Rensselaer Polytechnic Institute have developed a way to 3D print living skin, complete with blood vessels. The advancement, published online today in Tissue Engineering Part A, is a significant step toward creating grafts that are more like the skin our bodies produce naturally.

1 Nov 2019

Study provides a first look into black box of embryonic development

Little is known about the molecular and cellular events that occur during early embryonic development in primate species.

31 Oct 2019

New signaling systems discovered in human cells

The human cell has a wide variety of receptors on its surface that many molecules and therapeutic drugs can bind to in order to activate signals inside the cell to regulate different physiological functions. GPCRs are the largest - and a very important - family of receptors on human cells.

31 Oct 2019

Mutated version of DNA repair protein may illuminate its role in preventing cancer

Two trillion times each day, the cells in a typical human divide to replace old, damaged or dead cells. Before a cell divides, though, it makes an exact copy of its DNA, which will be passed on to the new cells.

31 Oct 2019

Mechanisms preserving cell identity are based on status of proteins housing DNA

The inheritance, not only of DNA, but of changes to proteins that package it, maintains the identity of cells as they multiply, a new study finds.

31 Oct 2019

Scientists identify protein that pulls the brake on nerve growth

During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists from the German Center for Neurodegenerative Diseases in Bonn have now identified a protein that regulates the growth of these extensions by pulling a brake.

31 Oct 2019