Cell Biology

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Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

A combination of peptides and antibiotics could be key to eliminating the parasite causing leishmaniasis and avoiding the toxicity to people and animals caused by current drugs.

16 Oct 2020

Antispastic drug candidate could offer new hope for millions of patients suffering from spasticity

First-in-class antispastic drug candidate to reach clinical phase is published in the prestigious life science journal, Cell. Drug candidate MPH-220 could mean new hope for millions of patients suffering from spasticity.

16 Oct 2020

Researchers discover mechanism that regulates neocortical dendrite development

The research group of Takao Kohno (Nagoya City University) and Mitsuharu Hattori (Nagoya City University), Takahiko Kawasaki (National Institute of Genetics), and Kazunori Nakajima (Keio University School of Medicine) found a new mechanism by which superficial neurons correctly develop their dendrites.

16 Oct 2020

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Vanderbilt University researchers have reported the counterintuitive discovery that certain chemotherapeutic agents used to treat tumors can have the opposite effect of tissue overgrowth in normal, intact mammary glands, epidermis and hair follicles.

16 Oct 2020

Study uncovers novel mechanical mechanism of metastatic cancer cells in substrates of different stiffness

During metastasis, cancer cells actively interact with microenvironments of new tissues. How metastatic cancer cells respond to new environments in the secondary tissues is a crucial question in cancer research but still remains elusive.

16 Oct 2020

Tech Spotlight honors ISSCR's stem cell based clinical trials guide

The ISSCR's Stem Cell-Based Clinical Trials: Practical Advice for Physicians and Ethics/Institutional Review Committees was honored today by Tech Spotlight at Harvard Kennedy School's Belfer Center.

16 Oct 2020

UofSC scientists identify biological triggers that promote quicker nerve regeneration

University of South Carolina scientists are exploring ways to make nerve regeneration happen faster and more successfully.

15 Oct 2020

NIH grants 4D Nucleome award to support research by Gladstone scientists

The National Institutes of Health has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, PhD, and Katie Pollard, PhD.

15 Oct 2020

Moffitt study uncovers how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread.

15 Oct 2020

Small molecule restores normal heart development in animal model with rare genetic disorder

A research team at the Greenwood Genetic Center has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML II), a rare genetic disorder. Progressive heart disease is commonly associated with ML II.

15 Oct 2020

Small RNA molecule controls major pathogenicity factors of H. pylori

More than half of the world's population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even lead to the development of stomach cancer.

15 Oct 2020

Researchers engineer cow muscle cells to produce plant nutrients

A group of researchers at Tufts University have genetically engineered cow muscle cells to produce plant nutrients not natively found in beef cells.

15 Oct 2020

Scientists find sensor protein that makes normal bladder function possible

A team co-led by scientists at Scripps Research has found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible.

14 Oct 2020

NYUAD researchers study the molecular basis of adipogenesis

The impairment of adipogenesis, the process in which fat cells (also known as adipocytes) accumulate to become fat tissue, can lead to many diseases such as diabetes, obesity, and heart conditions.

14 Oct 2020

FAU researchers receive NIH funding to analyze stem cell activation

Researchers from Florida Atlantic University's Schmidt College of Medicine hope to conquer a major limitation in the ability for scientists to engineer tissues for regenerative therapies for age-related and degenerative diseases.

14 Oct 2020

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even regulate our mood and immunity.

14 Oct 2020

Study provides new insight into unknown effects of factors that regulate blood vessel formation

A new study by researchers at the University of Eastern Finland provides novel insight into the previously unknown effects of factors regulating blood vessel formation.

14 Oct 2020

Modification of DNA structure plays key role in the recovery phase after DNA damage

A research team from Cologne has discovered that a change in the DNA structure - more precisely in the chromatin - plays a decisive role in the recovery phase after DNA damage.

14 Oct 2020

Physically squeezing cells can trigger cells to grow and divide faster

The closer people are physically to one another, the higher the chance for exchange, of things like ideas, information, and even infection.

14 Oct 2020

Cancer-killing T cells release chemicals to direct swarms towards tumors

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

13 Oct 2020

Cell Biology

Combination of peptides and antibiotics could be key to eliminating Leishmania parasites

Antispastic drug candidate could offer new hope for millions of patients suffering from spasticity

Researchers discover mechanism that regulates neocortical dendrite development

Researchers report the discovery of innate immune signaling pathway in fibroblasts

Study uncovers novel mechanical mechanism of metastatic cancer cells in substrates of different stiffness

Tech Spotlight honors ISSCR's stem cell based clinical trials guide

UofSC scientists identify biological triggers that promote quicker nerve regeneration

NIH grants 4D Nucleome award to support research by Gladstone scientists

Moffitt study uncovers how specific molecules promote cancer progression

Small molecule restores normal heart development in animal model with rare genetic disorder

Small RNA molecule controls major pathogenicity factors of H. pylori

Researchers engineer cow muscle cells to produce plant nutrients

Scientists find sensor protein that makes normal bladder function possible

NYUAD researchers study the molecular basis of adipogenesis

FAU researchers receive NIH funding to analyze stem cell activation

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Study provides new insight into unknown effects of factors that regulate blood vessel formation

Modification of DNA structure plays key role in the recovery phase after DNA damage

Physically squeezing cells can trigger cells to grow and divide faster

Cancer-killing T cells release chemicals to direct swarms towards tumors

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