Cell Biology

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Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

A research team headed by Prof. Dr. Sebastian Arnold and Jelena Tosic from the Faculty of Medicine at the University of Freiburg has now succeeded in deciphering basic molecular control mechanisms by which stem cells decide which embryonic cell types to turn into.

3 Dec 2019

Researchers show how the ductal system connecting digestive organs is formed

A specialized system of ducts transports bile and enzymes from the liver and pancreas to the intestine. In a new study, researchers from the University of Copenhagen have shown how this ductal system is formed. The new knowledge can help understanding how congenital diseases in that part of the body arise.

3 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

Scientists discover new principle for activation of cancer genes

Researchers have long known that some genes can cause cancer when overactive, but exactly what happens inside the cell nucleus when the cancer grows has so far remained enigmatic.

2 Dec 2019

New molecular mechanism involved in the regulation of cholesterol movement in cells found

Researchers from the University of Barcelona and the August Pi i Sunyer Biomedical Research Institute found a new molecular mechanism involved in the regulation of the cholesterol movement in cells, an essential process for a proper cell functioning.

2 Dec 2019

Purification scheme allows collection of elusive blood stem cells from zebrafish

Hematopoietic stem cells are multipotent cells that can develop into every type of blood cell in the body.

2 Dec 2019

New automated method helps identify cancer cell metabolism inhibitors

UCLA Jonsson Comprehensive Cancer Center researchers have developed a new automated method for testing hundreds of molecules at a time to find out which ones block cancer cells from consuming glucose - the sugars they need to spread and grow.

29 Nov 2019

Gene discovery in fruit flies could provide clues to counteract mitochondrial diseases

Scientists have identified a protein in fruit flies that can be targeted to reverse the effects of disease-causing mutations in mitochondrial genes. The discovery could provide clues about how to counteract human mitochondrial diseases, for which there is currently no cure.

28 Nov 2019

UCLA scientists discover link between a protein and human blood stem cell self-renewal

UCLA scientists have discovered a link between a protein and the ability of human blood stem cells to self-renew. In a study published today in the journal Nature, the team reports that activating the protein causes blood stem cells to self-renew at least twelvefold in laboratory conditions.

27 Nov 2019

Over €12 million funding to advance autophagy research

Four years ago, Collaborative Research Centre (CRC) 1177 on selective autophagy was established under the leadership of Goethe University - now the German Research Foundation has given the green light for its further funding.

27 Nov 2019

Potential new treatment for mitochondrial diseases discovered from fruit fly genes

Researchers have discovered a way to reverse the impact of disease-causing mitochondrial mutations by targeting fruit fly gene.

27 Nov 2019

What protects killer T cells from accidental death?

White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists from UCL and the Peter MacCallum Cancer Centre in Melbourne.

27 Nov 2019

Hibernators reveal genetic clues to better understand and treat obesity, metabolic disorders

Hibernation is one of nature's strangest quirks, inducing bears and other mammals to pack on massive weight- amounts that would be unhealthy for humans-;so they can survive months of slumber. Yet when these animals reemerge, they are as fit as ever.

27 Nov 2019

Study points to two types of motion that keeps cells in shape

The health of cells is maintained, in part, by two types of movement of their nucleoli, a team of scientists has found. This dual motion within surrounding fluid, it reports, adds to our understanding of what contributes to healthy cellular function and points to how its disruption could affect human health.

26 Nov 2019

Study shows how fiber spacing could control cell sticking

Researchers from the Mechanobiology Institute at the National University of Singapore have shown that cells can attach to the fibrous protein meshwork that surrounds them only if the fibers are spaced close enough.

26 Nov 2019

Stem cells do not take the day off on national holidays

While most of us are stuffing ourselves with turkey and pumpkin pie at home on Thanksgiving Day, the staff at one Cedars-Sinai laboratory will be on the job, feeding stem cells.

26 Nov 2019

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows.

26 Nov 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Fetuses may be able to see more than previously believed

By the second trimester, long before a baby's eyes can see images, they can detect light.

25 Nov 2019

Scientists record assembly of ribosomes in real time

A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes--the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms.

22 Nov 2019

Cell Biology

Freiburg scientists decipher basic molecular control mechanisms behind cellular identity

Researchers show how the ductal system connecting digestive organs is formed

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

Scientists discover new principle for activation of cancer genes

New molecular mechanism involved in the regulation of cholesterol movement in cells found

Purification scheme allows collection of elusive blood stem cells from zebrafish

New automated method helps identify cancer cell metabolism inhibitors

Gene discovery in fruit flies could provide clues to counteract mitochondrial diseases

UCLA scientists discover link between a protein and human blood stem cell self-renewal

Over €12 million funding to advance autophagy research

Potential new treatment for mitochondrial diseases discovered from fruit fly genes

What protects killer T cells from accidental death?

Hibernators reveal genetic clues to better understand and treat obesity, metabolic disorders

Study points to two types of motion that keeps cells in shape

Study shows how fiber spacing could control cell sticking

Stem cells do not take the day off on national holidays

Enzyme caspase-8 controls apoptosis, necroptosis and pyroptosis

Research shows how cilia and exocyst contribute to extracellular vesicle production

Fetuses may be able to see more than previously believed

Scientists record assembly of ribosomes in real time

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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