Cell Biology

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Enzyme SSH1 impairs the disposal of damaged tau and neurotoxic mitochondria

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

12 Oct 2020

Two well-known neurochemicals found to be involved in sub-second perception, cognition

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals - dopamine and serotonin - are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

12 Oct 2020

Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

12 Oct 2020

Understanding the production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation.

12 Oct 2020

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

12 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Computational biology algorithm could help optimize culture conditions required for cell therapy

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders.

12 Oct 2020

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Nerve cell activity indicates the confidence in decisions

Should I or shouldn't I? The activity of individual nerve cells in the brain tells us how confident we are in our decisions. This is shown by a recent study by researchers at the University of Bonn.

9 Oct 2020

Study reveals how ovaries maintain a female's fertility

Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality.

9 Oct 2020

Production of bone substitutes is less complicated than was previously thought

The way in which bone formation occurs needs to be redefined. This was revealed by Radboud university medical center researchers and their colleagues in a publication in Nature Communications.

8 Oct 2020

Researchers drastically reduce the harvest period of stem cell sheets

Stem cells are cell factories that constantly divide themselves to create new cells. Implanting stem cells in damaged organs can regenerate new tissues.

8 Oct 2020

NTHU research could have significant impact on the treatment of dementia

One of the causes of neurodegenerative diseases such as Parkinson's and Alzheimer's is the calcification of the basal nucleus of the brain, which blocks the membrane protein channels on the surface of brain cells, preventing the transmission of signal molecules and nutrients to the cells.

8 Oct 2020

Intracellular ATP levels in the cortical neurons vary with sleep–wake states, animal study shows

It is assumed that the brain has homeostatic mechanisms to prevent the depletion of cellular energy, required for all cellular activities.

7 Oct 2020

Research team discovers a new key player in long-term memory

A McGill-led multi-institutional research team has discovered that during memory consolidation, there are at least two distinct processes taking place in two different brain networks - the excitatory and inhibitory networks.

7 Oct 2020

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Cell senescence is a state of permanent cell cycle arrest that was initially defined for cells grown in cell culture. It plays a key role in age-associated organ dysfunction and age-related diseases such as cancer, but the in vivo pathogenesis is largely unclear.

7 Oct 2020

Cell Biology

Enzyme SSH1 impairs the disposal of damaged tau and neurotoxic mitochondria

Two well-known neurochemicals found to be involved in sub-second perception, cognition

Leaking components from broken muscle fibers activate 'satellite' muscle stem cells

Understanding the production of memory B cells and immune responses

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Computational biology algorithm could help optimize culture conditions required for cell therapy

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Nerve cell activity indicates the confidence in decisions

Study reveals how ovaries maintain a female's fertility

Production of bone substitutes is less complicated than was previously thought

Researchers drastically reduce the harvest period of stem cell sheets

NTHU research could have significant impact on the treatment of dementia

Intracellular ATP levels in the cortical neurons vary with sleep–wake states, animal study shows

Research team discovers a new key player in long-term memory

Researchers create p16-Cre ERT2 -tdTomato mouse model to characterize in vivo senescent cells

Scientists discover small molecules that may reduce cellular stress

Study offers explanation for why people's responses to the same drug vary widely

Direction and type of the force acting on a cell can alter gene expression

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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