Cell Biology

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'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Identification of MTK1 SAPKKK as new human oxidative stress sensor

In an aging society, various studies are being conducted to explore the relationship between active oxygen and aging-related diseases such as cancer, chronic inflammatory diseases, and metabolic syndrome.

28 Jul 2020

UMass Amherst biologists identify environmental sensing mechanism in cells

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Vaccination is the most effective public health measure to prevent infectious diseases. Vaccines can greatly reduce the risk of infection by working with the body's natural defenses to safely develop immunity to disease.

28 Jul 2020

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

A new study released today in STEM CELLS Translational Medicine shows promise of a major breakthrough in healing chronic foot ulcers resulting from diabetes.

28 Jul 2020

Researchers identify a miRNA that could promote hair regeneration

Researchers from North Carolina State University have identified a microRNA (miRNA) that could promote hair regeneration.

27 Jul 2020

New strategy may help guard beta cells, slow the onset of type 1 diabetes

Type 1 diabetes occurs when a person's own immune system destroys insulin-producing beta cells in the pancreas. In recent years, scientists have learned how to grow large volumes of replacement beta cells, but the researchers are still trying out many options to protect these cells against the immune attack.

27 Jul 2020

Novel label-free imaging method can differentiate active T cells from those off duty

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

27 Jul 2020

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

27 Jul 2020

Cancers caused by bacterial toxin might be preventable

Studying DNA mutations in cancers can help clarify how cancers develop and what makes cancer cells different from normal, healthy cells.

27 Jul 2020

Study provides new insights into the host cellular response to SARS-CoV-2 infection

The COVID-19 pandemic caused by the new coronavirus has created an unprecedented public health challenge globally. Little was known about how the infecting cells respond to the virus and how the virus hijacks the host cellular machinery.

27 Jul 2020

Continuous survival of neurons is intrinsically programmed during development

When our neurons -- the principle cells of the brain -- die, so do we.Most neurons are created during embryonic development and have no "backup" after birth. Researchers have generally believed that their survival is determined nearly extrinsically, or by outside forces, such as the tissues and cells that neurons supply with nerve cells.

25 Jul 2020

Researchers use new approach to unravel the mechanisms that lie behind tetraploidy

Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where cells are enabled to grow and divide out of control.

25 Jul 2020

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

A new study of human olfactory cells has revealed that viral invasion of supportive cells in the nasal cavity might be driving the loss of smell seen in some patients with COVID-19.

25 Jul 2020

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

24 Jul 2020

Scientists discover how coronavirus enters cells without encountering immune system resistance

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Olympus, a leading manufacturer of high-end research microscopes, and Cytosurge, a precision manufacturer of cell manipulation technologies, have entered a co-marketing agreement to become a complete system provider to the scientific community’s growing need for next-generation single-cell and CRISPR genetic manipulation solutions.

From Evident Corporation - Life Sciences 24 Jul 2020

Epigenomic modifications play key role in the development of lung tumors

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

23 Jul 2020

Study shows how mast cells regulate calcium levels to control the immune response

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium levels to keep the immune response under control.

23 Jul 2020

Cell Biology

'Synthetic lethality' could be exploited for cancer therapy

Identification of MTK1 SAPKKK as new human oxidative stress sensor

UMass Amherst biologists identify environmental sensing mechanism in cells

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

Researchers identify a miRNA that could promote hair regeneration

New strategy may help guard beta cells, slow the onset of type 1 diabetes

Novel label-free imaging method can differentiate active T cells from those off duty

EBV viral genome alters the host epigenetic landscape to drive stomach cancer

Cancers caused by bacterial toxin might be preventable

Study provides new insights into the host cellular response to SARS-CoV-2 infection

Continuous survival of neurons is intrinsically programmed during development

Researchers use new approach to unravel the mechanisms that lie behind tetraploidy

Study identifies mechanisms that underlie olfactory symptoms of COVID-19

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

Scientists discover how coronavirus enters cells without encountering immune system resistance

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Epigenomic modifications play key role in the development of lung tumors

Study shows how mast cells regulate calcium levels to control the immune response

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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