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FDA advisory panel to focus on dental amalgam's potential risk to vulnerable populations

The U.S. Food and Drug Administration today announced plans to hold an advisory panel on Dec. 14-15, 2010, to discuss several scientific issues that may affect the regulation of dental amalgam, used for direct filling of carious lesions or structural defects in teeth. The panel meeting will focus particularly on the potential risk to vulnerable populations, such as pregnant women, fetuses, and young children.

11 Jun 2010

Non-melanoma skin cancer is potential marker for survivors at risk for future malignant tumors

Childhood cancer survivors diagnosed later with non-melanoma skin cancer may be at increased risk for having a malignant tumor within 15 years, according to research led by St. Jude Children's Research Hospital investigators.

10 Jun 2010

New study finds propofol poses low risk for children undergoing research-driven imaging studies

A new study finds that propofol, a well-known anesthesia medication, has a low occurrence of adverse events for children undergoing research-driven imaging studies. The study, led by a pediatric anesthesiologist now at Children's National Medical Center, showed a low incidence of adverse events and no long term complications when propofol was used to sedate children for imaging studies that require them to be still for long periods of time.

10 Jun 2010

Copy number variants may cause autism: Study

An international consortium of researchers from more than 70 universities, including the University of Utah, has reported that a study of nearly 2,300 people supports the growing consensus that autism is caused in part by rare genetic changes called copy number variants (CNVs).

10 Jun 2010

New genetic discoveries from Autism Genome Project

An international consortium of researchers working under the auspices of Autism Speaks, the world's largest autism science and advocacy organization, has announced new genetic discoveries from the second phase of its collaborative study: the Autism Genome Project. The results were published today in the journal Nature, one of the world's most respected peer-reviewed scientific publications.

10 Jun 2010

World's largest DNA scan reveals new genetic changes in autistic children

The world's largest DNA scan for familial autism has uncovered new genetic changes in autistic children that are often not present in their parents. Identified in less than 1 percent of the population, these rare variants occur nearly 20 percent more in autistic children.

10 Jun 2010

Novel gene replacement therapy holds promise for Spinal Muscular Atrophy

Children who suffer from the devastating disease Spinal Muscular Atrophy are set to benefit from a new breakthrough in therapy developments by researchers at the University of Sheffield.

10 Jun 2010

$15 million sanctioned for replacement of school gas heaters not enough say organizations

The State Government of NSW has decided upon a $15 million replacement of nearly 100 school gas heaters especially targeting cold climate areas of NSW. The New South Wales Teachers Federation said in a statement that they will be urging the government to expand the programme to other areas replacing the unflued gas heaters in schools.

9 Jun 2010

Vemma kicks off second annual fundraising campaign for Children's Miracle Network

Vemma's second annual fundraising campaign for Children's Miracle Network kicks off this summer, June 1 - August 31, 2010. Funds raised will contribute to medical care, research and education throughout a network of 170 children's hospitals and foundations. Vemma NEXT, the company's liquid children's supplement, will play a key role in the fundraising effort.

9 Jun 2010

Discovery Labs reports preliminary results from Surfaxin Phase 2 trial in children with Acute Respiratory Failure

Discovery Laboratories, Inc., reports preliminary results from its Phase 2 clinical trial of Surfaxin® in children with Acute Respiratory Failure (ARF), a critical condition often caused in children by severe respiratory infections. The objective of the study was to evaluate the safety and tolerability of intratracheal administration of Surfaxin and to assess whether Surfaxin treatment could decrease the duration of mechanical ventilation in children with ARF.

9 Jun 2010

PulmoBind product candidate has potential for early diagnosis of PH in pediatric population

Pulmo BioTech Inc. has announced that early indications are that its PulmoBind product candidate has the potential for early diagnosis of Pulmonary Hypertension in the pediatric population. PH is a potentially life threatening and crippling disease; it is also very hard to diagnose.

9 Jun 2010

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

New techniques to detect chromosomal abnormalities can offer a higher degree of accuracy. Chromosomal abnormalities are a well-known cause of multiple congenital anomalies, and conventional methods of culture analysis have proven unsuccessful in 10% to 40% of cases. Comparative genomic hybridization (CGH) and fluorescent in situ hybridization (FISH) techniques were tested and found successful by analyzing tissue from children who had multiple congenital anomalies.

9 Jun 2010

CXCR4 protein restores brain damage in multiple sclerosis patients

A protein that helps build the brain in infants and children may aid efforts to restore damage from multiple sclerosis (MS) and other neurodegenerative diseases, researchers at Washington University School of Medicine in St. Louis have found.

9 Jun 2010

Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care accepted: Study

A study conducted by the nonprofit health research organization Altarum Institute suggests that Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care are broadly accepted by both child care providers and parents, and that challenges to implementing the policies can be overcome with support.

9 Jun 2010

Discovery Labs receives FDA guidance to gain Surfaxin approval for RDS in premature infants

Discovery Laboratories, Inc. announces today that it has received written guidance from the U.S. Food and Drug Administration (FDA) that is consistent with its ongoing, comprehensive preclinical program to resolve the sole remaining chemistry, manufacturing & control (CMC) issue necessary to potentially gain FDA marketing approval for Surfaxin® (lucinactant) for the prevention of Respiratory Distress Syndrome (RDS) in premature infants.

9 Jun 2010

UNITAID concerned about infant HIV medication shortage, drug company says supply is sufficient

Bristol-Myers Squibb's plans this month to close its plant in Meymac, France, that manufactures "the last therapeutic option" for HIV-positive babies has drawn criticism from UNITAID, Reuters reports. In an open letter published in the Lancet, UNITAID writes that "[c]losing this factory means that 4,000 to 7,000 babies currently enrolled in treatment plans in developing countries through UNITAID could be left without the medicines they need."

9 Jun 2010

Gates Foundation announces 5-year, $1.5 billion commitment for maternal, child health

During the Women Deliver conference on Monday Melinda Gates announced that the Bill & Melinda Gates Foundation "will spend $1.5 billion over the next five years on maternal and child health, family planning and nutrition in developing countries, a pledge that signals a new focus for the foundation known for concentrating on vaccines and AIDS," the Wall Street Journal reports (Jordan, 6/7).

9 Jun 2010

Columbia completes enrollment in PROCHIEVE 8% Phase III study to reduce preterm birth in short cervix women

Columbia Laboratories, Inc. today announced it completed enrollment in the PREGNANT (PROCHIEVE Extending GestatioN A New Therapy) Study last week. This randomized, double-blind, placebo controlled Phase III clinical study is evaluating the safety and efficacy of PROCHIEVE® 8% (progesterone gel) to reduce the risk of preterm birth in women with a cervical length between 1.0 and 2.0 centimeters as measured by transvaginal ultrasound at mid-pregnancy.

8 Jun 2010

UPMC Health Plan collaboration launches pediatric weight management program

A unique collaboration between UPMC Health Plan, Children's Community Pediatrics (CCP), and Children's Hospital of Pittsburgh of UPMC is utilizing a multidisciplinary team approach in the setting of the pediatrician's office to provide practical weight management strategies for children who are obese or overweight.

8 Jun 2010

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor. The research focused on a new way to attack the tumors by blocking the Hedgehog pathway that is linked to approximately 20 percent of medulloblastomas.

8 Jun 2010

Child Health News

FDA advisory panel to focus on dental amalgam's potential risk to vulnerable populations

Non-melanoma skin cancer is potential marker for survivors at risk for future malignant tumors

New study finds propofol poses low risk for children undergoing research-driven imaging studies

Copy number variants may cause autism: Study

New genetic discoveries from Autism Genome Project

World's largest DNA scan reveals new genetic changes in autistic children

Novel gene replacement therapy holds promise for Spinal Muscular Atrophy

$15 million sanctioned for replacement of school gas heaters not enough say organizations

Vemma kicks off second annual fundraising campaign for Children's Miracle Network

Discovery Labs reports preliminary results from Surfaxin Phase 2 trial in children with Acute Respiratory Failure

PulmoBind product candidate has potential for early diagnosis of PH in pediatric population

CGH, FISH techniques effective for postmortem analysis of fetuses, infants with congenital anomalies

CXCR4 protein restores brain damage in multiple sclerosis patients

Delaware's first-in-the-nation guidelines for nutrition and physical activity in child care accepted: Study

Discovery Labs receives FDA guidance to gain Surfaxin approval for RDS in premature infants

UNITAID concerned about infant HIV medication shortage, drug company says supply is sufficient

Gates Foundation announces 5-year, $1.5 billion commitment for maternal, child health

Columbia completes enrollment in PROCHIEVE 8% Phase III study to reduce preterm birth in short cervix women

UPMC Health Plan collaboration launches pediatric weight management program

Experimental drug that targets genetic makeup of tumor shows early signs of efficacy against medulloblastomas

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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