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Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Article reports increase in health care spending on children

Health care spending on children grew 56 percent between 1996 and 2013, with the most money spent in 2013 on inpatient well-newborn care, attention deficit/hyperactivity disorder (ADHD) and well-dental care, according to an article published online by JAMA Pediatrics.

28 Dec 2016

Study reports volume and cost of in-home care for children with special medical conditions

U.S. families provide nearly $36 billion annually in uncompensated medical care at home to children who have special health care needs, such as muscular dystrophy and cystic fibrosis, according to a large national study.

28 Dec 2016

Study highlights lack of nutritional standards for premixed infant cereals in lower-income countries

For parents around the world, premixed infant cereals--also known as complementary foods--can be a vital source of the solid food needed for healthy child growth after six months of age, when infants outgrow the nutrients provided by breast milk alone.

28 Dec 2016

Legalization of recreational marijuana impacts adolescent drug perception and use

Marijuana use increased and the drug's perceived harmfulness decreased among eighth- and 10th-graders in Washington after marijuana was legalized for recreational use by adults but there was no change among 12th-graders or among students in the three grades in Colorado after legalization for adults there, according to a new study published online by JAMA Pediatrics.

28 Dec 2016

Novel murine model helps shed light on mechanisms involved in reversible infantile liver failure

Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems.

27 Dec 2016

Potential drug could become first effective treatment option for Prader-Willi syndrome

Duke Health researchers have identified a drug-like small molecule that, in animal experiments, appears to be an effective treatment for a genetic disorder called Prader-Willi syndrome.

27 Dec 2016

Study tracks parents' unpaid time assisting children with special health care needs

About half of U.S. children with special health care needs -- 5.6 million children -- receive medical care from uncompensated family members worth billions of dollars, finds a large national study led by Boston Children's Hospital and the University of Southern California (USC).

27 Dec 2016

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

Drugs capable of activating silenced genes improve survival and growth outcomes in a mouse model of Prader-Willi syndrome, a rare and incurable childhood disease, according to a study funded by the National Institutes of Health.

27 Dec 2016

CSHL researcher-inventor hails FDA approval of new SMA drug

Within a week of Christmas day, a drug called nusinersen will be in the hands of doctors across the nation, who will use it, most urgently, to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA).

26 Dec 2016

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration has approved SPINRAZATM (nusinersen) under Priority Review for the treatment of spinal muscular atrophy (SMA) in pediatric and adult patients.

26 Dec 2016

MDA celebrates FDA approval of new spinal muscular atrophy drug

The Muscular Dystrophy Association today celebrated news of the U.S. Food and Drug Administration's decision to grant approval for nusinersen (brand name Spinraza), the first disease-modifying drug to treat the most common genetic cause of death in infants.

23 Dec 2016

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Investigators at the National Institutes of Health and international colleagues have identified a genetic immune disorder characterized by increased susceptibility and poor immune control of Epstein-Barr virus (EBV) and, in some cases, an EBV-associated cancer called Hodgkin's lymphoma.

23 Dec 2016

Child Health News

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Article reports increase in health care spending on children

Study reports volume and cost of in-home care for children with special medical conditions

Study highlights lack of nutritional standards for premixed infant cereals in lower-income countries

Legalization of recreational marijuana impacts adolescent drug perception and use

Novel murine model helps shed light on mechanisms involved in reversible infantile liver failure

Potential drug could become first effective treatment option for Prader-Willi syndrome

Study tracks parents' unpaid time assisting children with special health care needs

Experimental drug improves survival, growth outcomes in mouse model of Prader-Willi syndrome

CSHL researcher-inventor hails FDA approval of new SMA drug

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

MDA celebrates FDA approval of new spinal muscular atrophy drug

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

FDA approves first drug to treat children and adults with spinal muscular atrophy

Maternal smoking during pregnancy may affect children's kidney function

Past episode of kidney damage linked to increased risk for adverse pregnancy outcomes

Scientists identify gene variants causing unrecognized developmental disorder

New TSRI study shows how Piezo2 protein plays critical role in sensing lung expansion

Study discovers critical function of mother's immune cells in resisting preterm birth

Shortened antimicrobial treatment inferior to standard regimen for middle ear infections, study finds

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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