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Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

A non-invasive test to diagnose and monitor an inflammatory disease that injures the esophagus - called eosinophilic esophagitis or EoE - would replace the need for repeated endoscopy for a growing number of children and adults with this relatively new condition.

21 Apr 2016

Study explores effectiveness of cognitive behavioral therapy in primary care for depressed teenagers

Depressed teenagers who received cognitive behavioral therapy in their primary care clinic recovered faster, and were also more likely to recover, than teens who did not receive the primary care-based counseling, according to a Kaiser Permanente study published today in the journal Pediatrics.

21 Apr 2016

WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

During World Immunization Week 2016, held 24-30 April, the World Health Organization highlights recent gains in immunization coverage, and outlines further steps countries can take to “Close the Immunization Gap” and meet global vaccination targets by 2020.

21 Apr 2016

LAP defects may lead to lupus-like autoimmune disorder

A casual observation about size differences in mice has led to the discovery that defects in a process for digesting dead cells called LC3-associated phagocytosis (LAP) may lead to a lupus-like autoimmune disorder. St. Jude Children's Research Hospital scientists led the research, which appears as an advance online publication today in the scientific journal Nature.

21 Apr 2016

High fructose consumption during pregnancy may increase risk factors for heart disease in children

The negative health effects of consuming large amounts of fructose could impact several generations, according to researchers at The University of Texas Medical Branch at Galveston.

21 Apr 2016

Mother’s misperception of child's weight status linked to childhood obesity or malnutrition

A new study from the University of Houston Department of Health and Human Performance finds a child's risk for obesity or malnutrition may be tied to the mother's misperception of her child's weight status. A key to understanding this phenomenon may lie in how she regards her own weight status. Researchers say the situation shows that healthcare providers need to broaden their health care screenings.

21 Apr 2016

Experimental treatment shrinks rare pediatric tumor by 90%

When a baby's life was threatened by a rare pediatric cancer that would not respond to surgery or chemotherapy, doctors at Nemours Children's Hospital rapidly, successfully shrank the tumor by 90 percent using an experimental treatment, according to a new study published online in Pediatric Blood and Cancer.

20 Apr 2016

Novel strategy for obesity prevention in young children

A novel approach to preventing overweight/obesity in young children by replacing traditional, individual well-child care with a series of group visits that emphasize nutrition-focused interventions during the first 18 months of life was associated with a significantly reduced obesity rate at 2 years of age.

20 Apr 2016

Family interventions may help reduce children's genetic risks for obesity

Children's genetic risks for obesity may be reduced by interventions that strengthen family communication and help children manage their emotions and feelings of satiety, according to a new review of research on the problem.

20 Apr 2016

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

Seattle Children's is partnering on the launch of a study called the 'Oto-Acoustic Signals in SIDS'study that will investigate a possible association between Sudden Infant Death Syndrome (SIDS) and hearing alteration on the newborn hearing screen test.

19 Apr 2016

New research centre to tackle childhood obesity to be launched at University of Sydney’s CPC

A world-first research centre exclusively focused on tackling the childhood obesity epidemic will launch this week at the University of Sydney’s Charles Perkins Centre (CPC).

19 Apr 2016

New Lullaby Trust-funded study could prevent sudden, unexpected deaths of babies and children

An innovative new study funded by The Lullaby Trust is being launched, which could have profound implications for preventing the sudden and unexpected deaths of babies and children.

19 Apr 2016

Sugar compounds provide nutrient support for growth of infant gut microbes

UC Davis researchers have shown that an enzyme produced by beneficial microbes in babies' intestines is able to harvest specific sugar compounds from human breast-milk and cow's milk. The discovery identifies those sugars -- rather than associated protein compounds -- as the key to nourishing those important, health-promoting microbes.

18 Apr 2016

Cancer causing genetic condition risk in children lower than previously thought

The odds of children having a genetic condition which causes learning difficulties and tumours have been dramatically cut, thanks to genetic analysis led by The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust

18 Apr 2016

Study shows children with rare eye disease have greatest benefit from gene therapy

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal Ophthalmology, which showed that children had the greatest benefit from gene therapy for treatment of Leber congenital amaurosis (LCA) or severe early childhood onset retinal degeneration (SECORD).

18 Apr 2016

Exposure to homicide during pregnancy linked to increased risk of prematurity, low birth weight

In a recent paper published in the Journal of Development Economics, researchers Professor Marco Manacorda (Queen Mary University of London) and Dr Martin Foureaux Koppensteiner (University of Leicester) focused on evidence from the exposure of day-to-day violence in Brazil by analysing the birth outcomes of children whose mothers were exposed to local violence, as measured by homicide rates in small Brazilian municipalities and the neighbourhoods of the city of Fortaleza.

18 Apr 2016

More than half of U.S. adults believe today's kids have diminished emotional and mental health

More than half of adults believe children today are more stressed, experience less quality family time and have worse mental and emotional health than children in past generations, according to the C.S. Mott Children's Hospital National Poll on Children's Health.

18 Apr 2016

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

An observational study of pregnant women in Brazil to further understand Zika virus and its impact on reproductive health and fetus development have been launched. William Britt, M.D., professor of pediatric infectious diseases at the University of Alabama at Birmingham, leads the study, which complements his current research in Brazil on cytomegalovirus infection during pregnancy.

18 Apr 2016

Researchers determine mutations in RERE gene can cause many features linked with 1p36 deletions

One in 5,000 babies is born missing a small amount of genetic material from the tip of chromosome 1, a region called 1p36. Missing genes in the 1p36 region is a relatively common cause of intellectual disability.

18 Apr 2016

Child Health News

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Non-invasive test to diagnose EoE could replace need for repeated endoscopy

Study explores effectiveness of cognitive behavioral therapy in primary care for depressed teenagers

WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

LAP defects may lead to lupus-like autoimmune disorder

High fructose consumption during pregnancy may increase risk factors for heart disease in children

Mother’s misperception of child's weight status linked to childhood obesity or malnutrition

Experimental treatment shrinks rare pediatric tumor by 90%

Novel strategy for obesity prevention in young children

Family interventions may help reduce children's genetic risks for obesity

OASIS study to investigate link between SIDS and alteration on newborn hearing screen test

New research centre to tackle childhood obesity to be launched at University of Sydney’s CPC

New Lullaby Trust-funded study could prevent sudden, unexpected deaths of babies and children

Sugar compounds provide nutrient support for growth of infant gut microbes

Cancer causing genetic condition risk in children lower than previously thought

Study shows children with rare eye disease have greatest benefit from gene therapy

Exposure to homicide during pregnancy linked to increased risk of prematurity, low birth weight

More than half of U.S. adults believe today's kids have diminished emotional and mental health

New study to explore outcomes of pregnancy in Brazilian women with Zika virus

Researchers determine mutations in RERE gene can cause many features linked with 1p36 deletions

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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