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Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

Emerging therapies and promising new insights in the treatment of sickle cell disease represent a significant step toward improving outcomes and reducing the treatment burden for affected children and adults. Studies reporting these advances will be presented today at the 57th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2015

Tips to help lower risk of sports-related concussions

With scholastic sports such as football now in full swing, the potential for head injuries increases. Unfortunately, an estimated 3.8 million recreational and athletic concussions occur annually in the United States, according to the Centers for Disease Control and Prevention.

7 Dec 2015

Prophylactic antibiotics reduce risk of serious bacterial infections in children with ALL

Prophylactic antibiotics significantly reduce the risk of serious bacterial infections in children during the critical first month of treatment for acute lymphoblastic leukemia (ALL), the most common childhood cancer, according to a U.S. and Canadian study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

7 Dec 2015

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual meeting of the American Society of Hematology (abstract #260).

7 Dec 2015

Gene therapy can restore immune systems of children and young adults with SCID-X1

Gene therapy can safely rebuild the immune systems of older children and young adults with X-linked severe combined immunodeficiency (SCID-X1), a rare inherited disorder that primarily affects males, scientists from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have found.

7 Dec 2015

Research reveals genetic variants linked to treatment-related complications in children with blood diseases

Research to be presented today at the 57th American Society of Hematology Annual Meeting and Exposition reveals genetic variants that are associated with disease severity and treatment-related complications in children with blood diseases.

7 Dec 2015

Genetic variations associated with increased risk for osteonecrosis in young ALL patients

Variations in genes involved in normal bone development are associated with an 8- to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukemia (ALL), according to research led by St. Jude Children's Research Hospital and Children's Oncology Group investigators.

7 Dec 2015

Infant death risk higher for mothers who gain weight gain between pregnancies

An analysis of pregnancies recorded on the Swedish Medical Birth Register indicates that the risk of a baby dying in its first year of life is greater among mothers who gain weight between their first and second pregnancies compared with women who do not gain weight.

3 Dec 2015

Home intervention, education improve vaccination rates in at-risk children

A program by Stony Brook Children's Hospital that involves the use of trained community health workers on child immunization reveals that home intervention and education improves vaccine/immunization rates in at-risk children, including those living in poverty.

1 Dec 2015

New Northwestern Medicine project aims to understand effects of asthma, eczema on children

A new Northwestern Medicine project, "Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments" (AAD-PEPR), will focus on two common childhood diseases that affect almost 25 percent of American children under age 18.

1 Dec 2015

Scientists discover genetic causes of Goldenhar syndrome

Some children are born with cleft palates and, of those children, some have an asymmetrical face and a malformed ear. A team of scientists led by Berlin-based researcher Enno Klußmann of the Max Delbrück Center for Molecular Medicine has taken an important step towards discovering the genetic causes of this condition, known as Goldenhar syndrome.

30 Nov 2015

Researchers discover drug target and genetic pathway for graft-versus-host disease

A Seattle Children's Research Institute lab has discovered a genetic pathway that can be targeted with existing drugs to prevent graft-versus-host disease (GVHD), a common and deadly complication of bone marrow transplants.

30 Nov 2015

Lack of direct parental care affects brain development in left-behind children

Researchers in China have found that children who have been left without direct parental care for extended periods of time show larger gray matter volumes in the brain, according to a study being presented today at the annual meeting of the Radiological Society of North America.

30 Nov 2015

Bringing ill children from hospital to home can overwhelm family caregivers, affect children's recovery

Bringing acutely ill children home from the hospital can overwhelm family caregivers and affect a child's recovery and long-term health, according to research in the journal Pediatrics.

30 Nov 2015

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

The effect of a widespread genetic variant that increases the risk for childhood asthma can be neutralized. A new study shows that young infants are particularly responsive to the positive influence of exposure to farm dust.

27 Nov 2015

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

A new study has shown that taking progesterone supplements during the first trimester of pregnancy does not improve the chances of maintaining pregnancy among women who have a history of unexplained recurrent miscarriage.

26 Nov 2015

Obese children with NAFLD not meeting recommended physical activity levels

In a new study published today in the journal Nutrients, research from the University of Surrey and the Children's Liver Disease Foundation has found that both obese children and those with Non-Alcoholic Fatty Liver Disease (NAFLD) are not meeting the UK recommendations for a variety of vitamins and minerals.

26 Nov 2015

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

What can a rare genetic childhood disease teach us about cancer? Dr. Ayelet Erez of the Weizmann Institute of Science's Department of Biological Regulation says: "A single-mutation disease can act as a 'lens.' If we find exactly what malfunctions in the sick child, we can zoom in and understand the role of the same gene among the many genetic changes that accompany cancer."

26 Nov 2015

Research reveals MECP2 Duplication Syndrome can be reversed

The methyl CpG binding protein 2 gene (MECP2) produces a protein of the same name, the level of which is critical for normal brain function. Mutations leading to protein under-expression cause Rett Syndrome while gene duplication causing over-expression lead to MECP2 Duplication Syndrome. Both disorders are severely debilitating childhood neurological diseases.

26 Nov 2015

Researchers encourage more caution in use of ADHD medicine

Authors of new Cochrane Review remain uncertain about effect of widely used medicine on ADHD symptoms, despite large amount of research. Some evidence of increased sleeplessness and loss of appetite leads researchers to encourage more caution in use of methylphenidate.

26 Nov 2015

Child Health News

Research shows significant step toward improving outcomes, reducing treatment burden for SCD patients

Tips to help lower risk of sports-related concussions

Prophylactic antibiotics reduce risk of serious bacterial infections in children with ALL

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Gene therapy can restore immune systems of children and young adults with SCID-X1

Research reveals genetic variants linked to treatment-related complications in children with blood diseases

Genetic variations associated with increased risk for osteonecrosis in young ALL patients

Infant death risk higher for mothers who gain weight gain between pregnancies

Home intervention, education improve vaccination rates in at-risk children

New Northwestern Medicine project aims to understand effects of asthma, eczema on children

Scientists discover genetic causes of Goldenhar syndrome

Researchers discover drug target and genetic pathway for graft-versus-host disease

Lack of direct parental care affects brain development in left-behind children

Bringing ill children from hospital to home can overwhelm family caregivers, affect children's recovery

Specific environmental influences can neutralize effect of genetic variant that increases childhood asthma risk

Progesterone supplements fail to improve birth rate among women with a history of miscarriage

Obese children with NAFLD not meeting recommended physical activity levels

Exploring how absence of ASS1 protein affects sick children may provide a 'lens' on cancer

Research reveals MECP2 Duplication Syndrome can be reversed

Researchers encourage more caution in use of ADHD medicine

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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