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United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

United Therapeutics Corporation announced today that the United States Food and Drug Administration has approved Unituxin (dinutuximab) Injection (formerly called ch14.18), in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy.

10 Mar 2015

Afterschool programs help improve kids' health and physical fitness

Afterschool programs are emerging as an effective tool in the nation's ongoing battle against childhood obesity, according to a national household survey conducted by Shugoll Research for the Afterschool Alliance.

10 Mar 2015

Tourette syndrome patients may face second psychiatric disorder during their lifetimes

A new study of Tourette syndrome (TS) led by researchers from UC San Francisco and Massachusetts General Hospital has found that nearly 86 percent of patients who seek treatment for TS will be diagnosed with a second psychiatric disorder during their lifetimes, and that nearly 58 percent will receive two or more such diagnoses.

10 Mar 2015

UCLA, Sound Body Sound Mind Foundation partner to combat childhood obesity

UCLA Health System and the Sound Body Sound Mind Foundation have formed a partnership to provide practical ways to combat childhood obesity and promote healthy lifestyles in Los Angeles. The new entity, UCLA Health Sound Body Sound Mind, funded by a $3 million pledge from Sound Body Sound Mind, will replicate the foundation's existing program model.

10 Mar 2015

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

In a study published in the current online issue of JAMA Psychiatry, an international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report finding a highly accurate blood-based measure that could lead to development of a clinical test for autism spectrum disorder (ASD) risk in males as young as one to two years old.

10 Mar 2015

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the "genomic landscape" of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.

10 Mar 2015

Researchers study effects of pregnancy weight gain on childhood obesity risk among multi-ethnic youth

Unhealthy weight gain in pregnancy has been linked with infant size and body composition but until now little was known about its long-term association with childhood obesity among low-income and multi-ethnic youth.

10 Mar 2015

BPA exposure may cause tooth enamel abnormality in children

A tooth enamel abnormality in children, molar incisor hypomineralization (MIH), may result from exposure to the industrial chemical bisphenol A (BPA), authors of a new study conclude after finding similar damage to the dental enamel of rats that received BPA.

9 Mar 2015

Mother's age at childbirth may affect metabolic health of male children

A mother's age at childbirth may affect her male baby's birth weight as well as his adult glucose metabolism, new research shows.

9 Mar 2015

New study finds that fetus exposed to tobacco smoke faces diabetes risk in adulthood

A fetus exposed to tobacco smoke may be at increased risk for diabetes in adulthood, a new study of adult daughters finds.

9 Mar 2015

Fast food ads aimed at kids 'deceptive'

Fast food ads aimed at kids fail to de-emphasize toy premiums, making them deceptive by industry self-regulation standards. They also fail to emphasize healthy menu items, investigators at Dartmouth-Hitchcock's Norris Cotton Cancer Center have found.

9 Mar 2015

New study shows positive effects of gastric bypass surgery on obese adolescents

The skeletons of obese adolescents are usually more dense than those of normal weight teens, but after gastric bypass surgery, most return to normal density within two years, a new study finds.

9 Mar 2015

Low and high maternal thyroid hormone levels during pregnancy may affect infant's IQ

A new study finds that not only low but also high maternal thyroid hormone levels during early pregnancy may significantly lower the infant's IQ later in childhood. The study results, which will be presented Thursday at the Endocrine Society's 97th annual meeting in San Diego, suggest that the common practice of treating pregnant women who have mild thyroid hormone deficiency may pose unexpected risks to the developing baby's brain.

9 Mar 2015

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

The St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project reports that a highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene. The findings suggest that targeting the alteration is likely the key to improved survival.

9 Mar 2015

Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Obstructive sleep apnea (OSA) is prevalent in obese, pregnant Asian women with gestational diabetes, even when their diabetes is controlled by diet, a new study from Thailand finds.

9 Mar 2015

Africa's under-five children at greater risk of developing parasitic disease

Children under five living in sub-Saharan Africa are at greater risk than older children of developing a long-term parasitic disease, research suggests.

6 Mar 2015

Academy of Nutrition and Dietetics highlights positive effects of human milk on infants, maternal health

Human milk provides the best nutrition for most babies and breastfeeding provides the best nutrition for infants and very young children, according to an updated position paper from the Academy of Nutrition and Dietetics.

6 Mar 2015

Family-based programs prevent children from taking up smoking

A global review by Canada's University of Calgary and QUT into the effectiveness of family-based programs has found these programs can be highly effective in stopping children from taking up smoking.

6 Mar 2015

Phthalate exposure in pregnancy adversely affects masculinization of male genitals in babies

Exposure to hormone-altering chemicals called phthalates - which are found in many plastics, foods and personal care products - early in pregnancy is associated with a disruption in an essential pregnancy hormone and adversely affects the masculinization of male genitals in the baby, according to research led by the University of Pittsburgh Graduate School of Public Health.

6 Mar 2015

Multimodal approach to distinguish people with autism spectrum disorder

In an ancient Indian parable, a group of blind men touches different parts of a large animal to find what it is. Only when they share the descriptions of an ear, tail, trunk and leg do they know it is an elephant.

6 Mar 2015

Child Health News

United Therapeutics announces FDA approval of dinutuximab for treatment of high-risk neuroblastoma

Afterschool programs help improve kids' health and physical fitness

Tourette syndrome patients may face second psychiatric disorder during their lifetimes

UCLA, Sound Body Sound Mind Foundation partner to combat childhood obesity

Scientists find blood-based genomic biomarkers that could help identify young boys with ASD

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

Researchers study effects of pregnancy weight gain on childhood obesity risk among multi-ethnic youth

BPA exposure may cause tooth enamel abnormality in children

Mother's age at childbirth may affect metabolic health of male children

New study finds that fetus exposed to tobacco smoke faces diabetes risk in adulthood

Fast food ads aimed at kids 'deceptive'

New study shows positive effects of gastric bypass surgery on obese adolescents

Low and high maternal thyroid hormone levels during pregnancy may affect infant's IQ

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

Sleep apnea prevalent in obese, pregnant Asian women with gestational diabetes

Africa's under-five children at greater risk of developing parasitic disease

Academy of Nutrition and Dietetics highlights positive effects of human milk on infants, maternal health

Family-based programs prevent children from taking up smoking

Phthalate exposure in pregnancy adversely affects masculinization of male genitals in babies

Multimodal approach to distinguish people with autism spectrum disorder

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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