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Strong link between mortality and reduced innate immune responsiveness in critically ill patients

Investigators from 15 children's medical centers, including Nationwide Children's Hospital, observed and evaluated critically ill children with influenza to evaluate the relationships between levels of systemic inflammation, immune function and likelihood to die from the illness. The study appears in the January issue of Critical Care Medicine.

23 Jan 2013

New targeted enzyme replacement therapy can treat X-linked myotubular myopathy

A collaborative research team including a Medical College of Wisconsin (MCW) pediatric neuropathologist successfully mitigated some of the effects of a muscular disease by using a new targeted enzyme replacement therapy strategy from 4s3 Bioscience.

23 Jan 2013

Gene therapy does not slow or halt progression of cell loss in Leber congenital amaurosis

Independent clinical trials, including one conducted at the Scheie Eye Institute at the Perelman School of Medicine, have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused by mutations in a gene (RPE65) required for recycling vitamin A in the retina. Inherited retinal degenerative diseases were previously considered untreatable and incurable.

23 Jan 2013

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Bisphenol A (BPA) is a chemical compound that is included in the composition of plastics and resins. It is used, for example, in the manufacture of food containers such as bottles and babies' feeding bottles. It is also found in the protective films used inside food and drink cans and on till receipts where it used as a discloser. Significant levels of BPA have also been found in human blood, urine, amniotic fluid and placentas.

23 Jan 2013

Study finds 70% increase in type 1 diabetes among very young Philadelphian children

Over the past two decades, the incidence of type 1 diabetes in very young children under age 5 has increased by 70 percent in the city of Philadelphia, according to research from a University of Pennsylvania School of Nursing researcher who currently maintains the only US registry of diabetes in children that has collected data continuously since 1985.

23 Jan 2013

African health officials, child health experts gather for child survival summit in Ethiopia

"Representatives from African health ministries, the U.S. Agency for International Development (USAID), and child health experts gathered in Addis Ababa, Ethiopia, January 16-18 to share strategies to increase child survival rates," IIP Digital reports.

23 Jan 2013

Health workers resume polio vaccination efforts in Pakistan; Bill Gates discusses polio efforts in interview

"Health workers are back on the streets of Peshawar in Pakistan, defying death threats so they can vaccinate children against polio," Al Jazeera reports. "Nine of their colleagues were killed last month, and now they have been given extra security," the news service notes. "Despite the risks, many health workers say they must carry out this important task," Al Jazeera's Osama Bin Javaid states in an accompanying video.

23 Jan 2013

Research on dystrophin gene sequence could lead to treatments for Duchenne muscular dystrophy

Muscular dystrophy is caused by the largest human gene, a complex chemical leviathan that has confounded scientists for decades. Research conducted at the University of Missouri and described this month in the Proceedings of the National Academy of Sciences has identified significant sections of the gene that could provide hope to young patients and families.

23 Jan 2013

Single dose of seasonal flu vaccine is safe for egg allergic children

Egg allergic children, including those with a history of anaphylaxis to egg, can safely receive a single dose of the seasonal influenza vaccine, according to a new study from the University of Michigan.

23 Jan 2013

Nationwide Children's to establish EC145 helicopter for neonatal and pediatric transports

Nationwide Children's Hospital is expanding their critical care transport services by establishing a fully dedicated helicopter for neonatal and pediatric transports.

23 Jan 2013

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

Using a brain-imaging technique that examines the entire infant brain, researchers have found that the anatomy of certain brain areas - the hippocampus and cerebellum - can predict children's language abilities at 1 year of age.

22 Jan 2013

CHLA, House Research Institute receive FDA approval to begin pediatric ABI clinical trial

L.A.-based House Research Institute and Children's Hospital Los Angeles announced today that the United States Food and Drug Administration (FDA) has given final approval to begin a clinical trial of an Auditory Brainstem Implant (ABI) procedure for children.

22 Jan 2013

Suppression of immune system function can occur in influenza patients

22 Jan 2013

Physical activity policies: an interview with Dr Nick Cavill

Our bodies were designed to be active. The human body is not meant to spend long periods of time sitting but that’s what our modern lives have led us to do. The result has been the increase in obesity seen across the world, and up to 20 other conditions including cardiovascular disease and diabetes.

22 Jan 2013

Kaiser Permanente study examines increasing prevalence of undervaccination

In a new study published today in JAMA Pediatrics (formerly Archives of Pediatrics and Adolescent Medicine), Kaiser Permanente researchers found that 49 percent of children ages 2-24 months did not receive all recommended vaccinations or did not get vaccinated according to the Advisory Committee on Immunization Practices schedule.

22 Jan 2013

Hospital admissions for childhood asthma reduces after smoke-free legislation

The introduction of smoke-free legislation in England was immediately followed by a fall in the number of children admitted to hospital with asthma symptoms, a new study has found.

22 Jan 2013

Study finds high ADHD diagnosis rates among non-Hispanic children between 2001 and 2010

The rate of children diagnosed with Attention Deficit Hyperactivity Disorder rose dramatically between 2001 and 2010 with non-Hispanic white children having the highest diagnosis rates, according to a Kaiser Permanente study published in the journal JAMA Pediatrics (formerly Archives of Pediatrics and Adolescent Medicine).

22 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene mutations—mutations that would suggest new targets for neuroblastoma treatment. Instead, say the researchers, they have now refocused on how neuroblastoma tumors evolve in response to medicine and other factors.

21 Jan 2013

Low blood flow to the premature brain disrupts cells' ability to fully mature

Physician-scientists at Oregon Health & Science University Doernbecher Children's Hospital are challenging the way pediatric neurologists think about brain injury in the pre-term infant. In a study published online in the Jan. 16 issue of Science Translational Medicine, the OHSU Doernbecher researchers report for the first time that low blood and oxygen flow to the developing brain does not, as previously thought, cause an irreversible loss of brain cells, but rather disrupts the cells' ability to fully mature.

19 Jan 2013

Child Health News

Strong link between mortality and reduced innate immune responsiveness in critically ill patients

New targeted enzyme replacement therapy can treat X-linked myotubular myopathy

Gene therapy does not slow or halt progression of cell loss in Leber congenital amaurosis

Exposure of human f-tal testicles to bisphenol A reduces testosterone production

Study finds 70% increase in type 1 diabetes among very young Philadelphian children

African health officials, child health experts gather for child survival summit in Ethiopia

Health workers resume polio vaccination efforts in Pakistan; Bill Gates discusses polio efforts in interview

Research on dystrophin gene sequence could lead to treatments for Duchenne muscular dystrophy

Single dose of seasonal flu vaccine is safe for egg allergic children

Nationwide Children's to establish EC145 helicopter for neonatal and pediatric transports

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

CHLA, House Research Institute receive FDA approval to begin pediatric ABI clinical trial

Suppression of immune system function can occur in influenza patients

Physical activity policies: an interview with Dr Nick Cavill

Kaiser Permanente study examines increasing prevalence of undervaccination

Hospital admissions for childhood asthma reduces after smoke-free legislation

Study finds high ADHD diagnosis rates among non-Hispanic children between 2001 and 2010

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Study refocuses on how neuroblastoma tumors evolve in response to medicine and other factors

Low blood flow to the premature brain disrupts cells' ability to fully mature

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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