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Rutgers scientists reveal structure of TB drug target and identify new inhibitors

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant tuberculosis bacteria.

7 Apr 2017

New research initiative aims at reducing HIV infection and transmission among vulnerable youth

The University of Chicago Medicine's Center for Interdisciplinary Inquiry and Innovation in Sexual and Reproductive Health has launched a research initiative aimed at reducing HIV infection and transmission among vulnerable youth of color, including young men who have sex with men and young transgender women.

6 Apr 2017

Case Western Reserve University researchers aim to treat oral complications of HIV

While advances in HIV treatment have dramatically improved patient lifespans and quality of life, nagging side effects remain; among the most common is chronic inflammation--essentially, when an immune system imbalance causes the body to attack itself.

6 Apr 2017

Health officials increase prevention efforts to address serious threats of Zika virus

State and territorial health officials are redoubling prevention efforts to address the serious public health threats associated with Zika virus and to protect the health of mothers and babies.

6 Apr 2017

New paper-based device shows great potential for whooping cough diagnosis in low-resource settings

A mother lovingly cradles her sick baby in her arms. As the infant coughs and gasps for air, his anguished mother looks up and warns that the safest place for your baby is not always in your arms.

6 Apr 2017

Epigem partners with Northumbria University to develop disposable TB testing kit

Leading micro-engineering company Epigem today announced a new Knowledge Transfer Partnership with Northumbria University to develop a cost-effective tuberculosis (TB) testing kit.

From Epigem Ltd. 6 Apr 2017

Overall balance of bacteria on skin may be key factor for acne development

Researchers, led by Dr Huiying Li, an associate professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA, used over-the-counter pore cleansing strips to obtain skin follicle samples from 72 individuals: 38 with acne and 34 who didn't have the disease.

6 Apr 2017

Antibody treatment protects non-human primates against deadly Marburg and Ravn viruses

An antibody treatment successfully protected nonhuman primates against the deadly Marburg and Ravn viruses even when given five days after becoming infected, according to the latest findings of a collaborative team from The University of Texas Medical Branch at Galveston, Mapp Biopharmaceutical Inc., and Vanderbilt University. The findings are now available in Science Translational Medicine.

6 Apr 2017

Novel point-of-care testing strategy can speed up treatment for respiratory illnesses

Doctors and researchers in Southampton have developed a novel way of using a swab test which can rapidly diagnose flu and other viral infections in patients with severe respiratory conditions - resulting in shorter courses of antibiotics and less time in hospital.

5 Apr 2017

Experimental treatment cures Marburg and Ravn virus infection in animals

Scientists funded by the National Institutes of Health have found that an experimental treatment cured 100 percent of guinea pigs and rhesus monkeys in late stages of infection with lethal levels of Marburg and Ravn viruses, relatives of the Ebola virus.

5 Apr 2017

Zika-related birth defects reported by 1 in 10 US based pregnant women infected by the virus in 2016

The new Vital Signs report, released by the Centers for Disease Control and Prevention (CDC), has reported that of 250 pregnant women confirmed with Zika infection in 2016, approximately 1 in 10 of them had a fetus or infant with virus-related birth defects. Thisreport is the first of its kind, to present an analysis from a sample of US women with a definite case of Zika infection during pregnancy.

5 Apr 2017

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

As the population of people living with HIV in the United States ages, the burden of cancer for these patients is expected to shift away from cancers linked to AIDS and toward malignancies that affect the general population, according to a new study led by a University of North Carolina at Chapel Hill researcher.

5 Apr 2017

Dose sparing could increase vaccine availability without compromising safety

The currently licensed seasonal trivalent influenza vaccines contain 15 micrograms of viral hemagglutinin protein per strain for adults, and up to 60 micrograms for elderly individuals; however, due to recent shortages, reducing these doses would be highly desirable.

5 Apr 2017

CBT program to promote alcohol abstinence among HIV-infected people could help save money

Public health research shows that alcohol may be a factor in more than 13 percent of deaths due to infectious diseases, including HIV.

5 Apr 2017

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

As the Zika virus continues to spread rapidly across the globe, it might pose a particular risk to people previously infected with two related viruses, dengue and West Nile, researchers at the Icahn School of Medicine at Mount Sinai have found.

5 Apr 2017

KU Leuven-led consortium to develop new vaccine that protects against rabies and yellow fever

Rabies and yellow fever claim ten thousands of lives each year. Vaccines already exist but various drawbacks that hinder their efficient distribution.

4 Apr 2017

Public distrust in government-led initiatives could hinder efforts to stop Zika, other infectious diseases

Nearly half of New Hampshire residents surveyed believe scientists adjust their findings to get the answers they want, and these people are significantly less likely to trust the Centers for Disease Control (CDC) as a source of information on the Zika virus, according to new research released by the Carsey School of Public Policy at the University of New Hampshire.

4 Apr 2017

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Australia has the potential to eradicate hepatitis C in the next 10–15 years, according to Associate Professor Simone Strasser, gastroenterologist at Royal Prince Alfred Hospital in Sydney.

4 Apr 2017

Meningitis bacterium appears to be adapting to urogenital environment, DNA analysis shows

Neisseria meningitidis, a bacterium usually associated with meningitis and sepsis, is the cause of a recent cluster of sexually transmitted infections in Columbus, Ohio and in other US cities. The bacterium appears to be adapting to a urogenital environment, an analysis of the organism's DNA shows.

4 Apr 2017

Research finding could set stage for potential development of new antimicrobial drugs

Research teams from the National Institutes of Health and abroad have identified the first inhibitor of an enzyme long thought to be a potential drug target for fighting disease-causing parasites and bacteria.

3 Apr 2017

Disease/Infection News

Rutgers scientists reveal structure of TB drug target and identify new inhibitors

New research initiative aims at reducing HIV infection and transmission among vulnerable youth

Case Western Reserve University researchers aim to treat oral complications of HIV

Health officials increase prevention efforts to address serious threats of Zika virus

New paper-based device shows great potential for whooping cough diagnosis in low-resource settings

Epigem partners with Northumbria University to develop disposable TB testing kit

Overall balance of bacteria on skin may be key factor for acne development

Antibody treatment protects non-human primates against deadly Marburg and Ravn viruses

Novel point-of-care testing strategy can speed up treatment for respiratory illnesses

Experimental treatment cures Marburg and Ravn virus infection in animals

Zika-related birth defects reported by 1 in 10 US based pregnant women infected by the virus in 2016

Number of HIV-positive cancer patients in the U.S. projected to decrease through 2030

Dose sparing could increase vaccine availability without compromising safety

CBT program to promote alcohol abstinence among HIV-infected people could help save money

Zika virus may pose increased risk to people previously infected with dengue and West Nile, study finds

KU Leuven-led consortium to develop new vaccine that protects against rabies and yellow fever

Public distrust in government-led initiatives could hinder efforts to stop Zika, other infectious diseases

Australia has potential to eradicate hepatitis C in 10–15 years, says expert

Meningitis bacterium appears to be adapting to urogenital environment, DNA analysis shows

Research finding could set stage for potential development of new antimicrobial drugs

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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