Disease/Infection News

RSS

Novel mechanism may help explain the virulence of 1918 'Spanish' flu

While yearly outbreaks of flu kill about 250,000 to 500,000 people worldwide, the 1918 "Spanish" flu infected one-third of the world's population and killed 50 million to 100 million. Chad Petit, Ph.D., assistant professor in the University of Alabama at Birmingham Department of Biochemistry and Molecular Genetics, has discovered a novel mechanism for one 1918 flu virus protein that may help explain the virulence of that unusually deadly pandemic.

23 Sep 2015

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

A $375,000 grant from the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation was awarded to Subramanian Dhandayuthapani, Ph.D., an associate professor in the Center of Emphasis in Infectious Diseases at the Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, to develop genetically altered vaccines against tuberculosis (TB).

23 Sep 2015

Optum and AMGF launch pilot collaborative to enhance adult vaccination rates

The American Medical Group Foundation (AMGF) and Optum, with support from Pfizer, are launching a pilot collaborative to improve adult vaccination rates.

23 Sep 2015

Older pneumonia patients can benefit from ICU admission

When an older person gets hospitalized for pneumonia, where's the best place to care for them? New research findings about deaths and health care costs in such patients fly in the face of conventional wisdom - and could change where doctors decide to treat them.

23 Sep 2015

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Longing to find a cure for cancer, HIV and other yet incurable diseases, researchers have already tried out hundreds of drugs, each requiring preclinical and clinical testing with live subjects. How many chemical agents more to try? Moving at such rate, will we find the cure during our lifetime? One of the easiest ways to speed up the drug development process is to simply perform it outside of the living body (e.g., by watching the substances react with the smallest pieces of live tissue and thus quickly predicting the overall effect it will make to the body when inside).

23 Sep 2015

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

A strain of E. coli became a potentially fatal infection in the UK around 30 years ago, when it acquired a powerful toxin, a gene study has revealed.

22 Sep 2015

Donor and patient age more important in determining kidney transplant success

Infection by virus cytomegalovirus (CMV) is a common and major complication following kidney transplantation. Previous studies have related CMV infection with increased kidney transplant failure and reduced patient survival. However, a new study published in the American Journal of Physiology—Renal Physiology reports that the age of the donor and the recipient, not CMV infection, are more important factors in determining transplant success.

22 Sep 2015

T2 Biosystems' T2Candida Panel more sensitive than blood culture for monitoring patients on antifungal therapy

T2 Biosystems, Inc. a company developing innovative diagnostic products to improve patient health, today announced that data on its T2Candida Panel was presented today at the Interscience Conference on Antimicrobial Agents and Chemotherapy and the International Society of Chemotherapy joint meeting in San Diego, CA.

22 Sep 2015

AmpliPhi's novel bacteriophage therapy demonstrates comparable efficacy to vancomycin in S. aureus lung infection model

AmpliPhi Biosciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resistant infections, today announced experimental results highlighting that its prototype bacteriophage cocktail demonstrated comparable efficacy to vancomycin in reduction of Staphylococcus aureus in a murine lung infection model.

22 Sep 2015

WHO and the Government of Saudi Arabia work together to care for health issues of hajj pilgrims

As an estimated 2 million Muslims from 184 countries gather in Saudi Arabia’s holy city of Mecca to take part in the annual hajj pilgrimage, months of preparations to care for health issues of pilgrims are also coming together.

22 Sep 2015

Scientists uncover how embryonic stem cells inhibit virus expression

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, Singapore, have uncovered the mechanisms which embryonic stem cells employ to inhibit virus expression.

22 Sep 2015

Outbreak of Bordetella parapertussis occurred in Southeastern Minnesota in 2014: Study

Study reports that an outbreak of Bordetella parapertussis occurred in 2014 in Southeastern Minnesota, in the months of October through December. This research is presented at ASM's 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC/ICC).

22 Sep 2015

Protein-based modular system could help detect viral infection or kill cancer cells

MIT biological engineers have developed a modular system of proteins that can detect a particular DNA sequence in a cell and then trigger a specific response, such as cell death.

22 Sep 2015

New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Researchers at The Medicines Company presented data from a multi-national cohort that demonstrates the mortality and morbidity, and poor outcomes, associated with current therapies in patients with infections due to carbapenem-resistant Enterobacteriaceae (CRE). The data from this analysis has guided the design of the company’s on-going clinical studies of its Phase 3 compound, CARBAVANCE® (meropenem/RPX7009) and was presented at the Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) and the International Congress of Chemotherapy and Infection (ICC) joint meeting in San Diego, CA.

22 Sep 2015

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Research comparing clinical outcomes between patients receiving nafcillin and cefazolin for treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia shows that overall treatment failure rate among patients receiving cefazolin was no worse than nafcillin, and significantly fewer adverse effects were documented for those receiving cefazolin.

22 Sep 2015

Results from phase 3 women-only HIV study show improved safety, efficacy of Stribild drug

Results from the first phase 3 HIV study to enroll only women show improved safety and efficacy of the drug Stribild over multi-pill antiretroviral drug regimens. The research was presented at ASM's 55th Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC/ICC).

21 Sep 2015

New Locilex microbiology data presented at ICAAC/ICC 2015 scientific conference

Dipexium Pharmaceuticals, Inc., a late-stage pharmaceutical company focused on the development and commercialization of Locilex (pexiganan cream 0.8%), and research collaborators, JMI Laboratories, announced that new Locilex microbiology data were presented at the American Society for Microbiology's Interscience Conference of Antimicrobial Agents and Chemotherapy and International Society of Chemotherapy's International Congress of Chemotherapy and Infection (ICAAC/ICC 2015) scientific conference in San Diego, California, September 17-21, 2015.

21 Sep 2015

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines, today announced that it has entered a collaboration with German biotechnology company Cilian AG to develop a solid dose formulation of Cilian's experimental recombinant influenza vaccine, CiFlu, for delivery using Glide's patient-friendly SDI delivery device.

21 Sep 2015

Urinary tract infections could be treated more efficiently using DNA sequencing device

Urinary tract infections (UTIs) could be treated more quickly and efficiently using a DNA sequencing device the size of a USB stick - according to research from the University of East Anglia.

From Oxford Nanopore Technologies 21 Sep 2015

New study reshapes how scientists look at dengue virus

A new study is reshaping how scientists look at and understand a deadly virus. An international consortium of scientists, including researchers from the University of Texas Medical Branch at Galveston, worked to map out the antigenic differences in various strains of dengue virus.

19 Sep 2015

Disease/Infection News

Novel mechanism may help explain the virulence of 1918 'Spanish' flu

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

Optum and AMGF launch pilot collaborative to enhance adult vaccination rates

Older pneumonia patients can benefit from ICU admission

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Gene study reveals how a strain of E. coli evolved to become potentially fatal infection

Donor and patient age more important in determining kidney transplant success

T2 Biosystems' T2Candida Panel more sensitive than blood culture for monitoring patients on antifungal therapy

AmpliPhi's novel bacteriophage therapy demonstrates comparable efficacy to vancomycin in S. aureus lung infection model

WHO and the Government of Saudi Arabia work together to care for health issues of hajj pilgrims

Scientists uncover how embryonic stem cells inhibit virus expression

Outbreak of Bordetella parapertussis occurred in Southeastern Minnesota in 2014: Study

Protein-based modular system could help detect viral infection or kill cancer cells

New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Study compares effectiveness of nafcillin and cefazolin in patients with MSSA blood stream infections

Results from phase 3 women-only HIV study show improved safety, efficacy of Stribild drug

New Locilex microbiology data presented at ICAAC/ICC 2015 scientific conference

Glide Technologies, Cilian collaborate to develop solid dose formulation of recombinant influenza vaccine

Urinary tract infections could be treated more efficiently using DNA sequencing device

New study reshapes how scientists look at dengue virus

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News