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Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs.

9 Jun 2016

Understanding DNA scrunching could help develop novel ways to fight infections

Evidence of DNA "scrunching" may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, and Columbia University.

9 Jun 2016

Researchers deploy mobile DNA sequencing laboratories to help combat Zika virus spread in Brazil

Researchers from the University of Birmingham are working with health partners in Brazil to combat the spread of Zika virus by deploying a pair of mobile DNA sequencing laboratories on a medical 'road trip' through the worst-hit areas of the country.

From Oxford Nanopore Technologies 8 Jun 2016

Research reveals complicated love story between bacterial virulence and antibiotic resistance

It's thought that antibiotic resistance is associated with a fitness cost, meaning that bacteria that develop antibiotic resistance must sacrifice something in order to do so. Because of this, proper use of antibiotics should result in susceptible strains eventually replacing resistant ones.

8 Jun 2016

Screening for syphilis in persons at risk for infection provides substantial benefit

The U.S. Preventive Services Task Force has found convincing evidence that screening for syphilis infection in asymptomatic, nonpregnant persons at increased risk for infection provides substantial benefit. The report appears in the June 7 issue of JAMA.

8 Jun 2016

Novel enzyme immunoassay helps diagnose HCV infection in one simple step

The current standard in diagnosing Hepatitis C virus (HCV) infection requires two sequential steps that make it suboptimal, costly, inconvenient, time consuming, and globally not widely available or affordable.

8 Jun 2016

New immunization approach may one day wipe out pneumonia, meningitis

A new vaccine allows pneumonia-causing bacteria to colonize inside the body, springing into action only if the bacteria pose a threat.

8 Jun 2016

Sexual transmission of Ebola virus could potentially reignite disease outbreak

Sexual transmission of the Ebola virus could have a major impact on the dynamics of the disease, potentially reigniting an outbreak that has been contained by public health interventions, according to research by University of Georgia ecologists just published in the Royal Society journal Biology Letters.

8 Jun 2016

Researchers develop new, complete Ebola virus map based on bio-geographical analyses

To be prepared for new Ebola virus disease cases, it is fundamental to start by identifying the range of the virus and the regions that are more favorable for its propagation.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

Hepatocellular carcinoma, the most common type of liver cancer, is increasing in incidence in the United States, and infection with the Hepatitis B virus (HBV) causes about 50 percent of cases.

7 Jun 2016

Tanaka develops world's first kit to directly detect ZIKA virus in blood

Tanaka Holdings Co., Ltd. announced today that Tanaka Kikinzoku Kogyo K.K., which operates the Tanaka Precious Metals manufacturing business, has developed the world's first kit able to directly detect the ZIKA virus in blood. The kit is capable of rapid ZIKV detection in just 10 to 15 minutes.

7 Jun 2016

New systems-based strategy may help accelerate TB drug discovery

The rise in multi-drug resistant (MDR) and extremely drug resistant (XDR) strains of Mycobacterium tuberculosis (MTB) is becoming a major cause of global health concern for treating tuberculosis, which affects a third of the global population.

7 Jun 2016

New study identifies PDGFRα as key molecule for HCMV viral entry

A publication in the scientific journal Nature Microbiology identifies PDGFRα as the receptor for the trimeric gHgLgO complex of Human cytomegalovirus (HCMV).

7 Jun 2016

Researchers examine pan-genome of deadly Staph bacteria

Staphylococcus aureus bacteria are the leading cause of skin, soft tissue and several other types of infections. Staph is also a global public threat due to the rapid rise of antibiotic-resistant strains, including methicillin-resistant Staphylococcus aureus or MRSA.

7 Jun 2016

NHS England takes too long to commission PrEP for HIV prevention

An effective treatment that can prevent HIV infection and reduce the human and financial costs of the preventable condition is taking too long to be commissioned and made available on the NHS, warns Deborah Gold, chief executive of the National Aids Trust, in an article published by The BMJ today.

7 Jun 2016

Zika virus directly infects brain progenitor cells in newborns to cause neurological problems

The mosquito-borne Zika virus linked to microcephaly and other neurological problems in newborns of affected mothers directly infects the brain progenitor cells destined to become neurons, UT Southwestern Medical Center researchers report in a study published online today in Cell Reports.

6 Jun 2016

Alabama physician recommends childbearing-age women to take precautions against Zika virus

As concerns about the Zika virus rise among women of childbearing age in the United States, Joseph Biggio, M.D., director of the University of Alabama at Birmingham Division of Maternal-Fetal Medicine, wants those who are pregnant or trying to conceive to take precautions.

6 Jun 2016

Bacteriophage combinations show therapeutic potential in reducing C. difficile infections

A new University of Leicester study has confirmed the therapeutic potential of bacteriophage combinations to treat highly infectious bacteria C. difficile infections (CDI) while retaining a healthy gut.

6 Jun 2016

Improved research tool may open door to effective HIV vaccine designs

Vaccines are usually medicine's best defense against the world's deadliest microbes. However, HIV is so mutable that it has so far effectively evaded both the human immune system and scientists' attempts to make an effective vaccine to protect against it.

6 Jun 2016

Disease/Infection News

Mathematical approach can help achieve optimal dosing for various drugs

Understanding DNA scrunching could help develop novel ways to fight infections

Researchers deploy mobile DNA sequencing laboratories to help combat Zika virus spread in Brazil

Research reveals complicated love story between bacterial virulence and antibiotic resistance

Screening for syphilis in persons at risk for infection provides substantial benefit

Novel enzyme immunoassay helps diagnose HCV infection in one simple step

New immunization approach may one day wipe out pneumonia, meningitis

Sexual transmission of Ebola virus could potentially reignite disease outbreak

Researchers develop new, complete Ebola virus map based on bio-geographical analyses

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

Tanaka develops world's first kit to directly detect ZIKA virus in blood

New systems-based strategy may help accelerate TB drug discovery

New study identifies PDGFRα as key molecule for HCMV viral entry

Researchers examine pan-genome of deadly Staph bacteria

NHS England takes too long to commission PrEP for HIV prevention

Zika virus directly infects brain progenitor cells in newborns to cause neurological problems

Alabama physician recommends childbearing-age women to take precautions against Zika virus

Bacteriophage combinations show therapeutic potential in reducing C. difficile infections

Improved research tool may open door to effective HIV vaccine designs

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