Disease/Infection News

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Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

University of Toronto Assistant Professor of Pharmacy Keith Pardee and an international team of collaborators, including scientists from the Wyss Institute at Harvard University, have developed a low-cost, easy-to-use diagnostic platform for detecting the Zika virus.

9 May 2016

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

The U.S. Centers for Disease Control and Prevention recently concluded that Zika virus infection in pregnant women can stunt neonatal brain development, leading to babies born with abnormally small heads, a condition known as microcephaly. Now, for the first time, researchers at University of California San Diego School of Medicine have determined one way Zika infection can damage developing brain cells.

9 May 2016

New antibody-based therapy may provide better strategy for long-term control of HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

9 May 2016

MIT researchers develop innovative paper-based test to diagnose Zika virus

A new paper-based test developed at MIT and other institutions can diagnose Zika virus infection within a few hours. The test, which distinguishes Zika from the very similar dengue virus, can be stored at room temperature and read with a simple electronic reader, making it potentially practical for widespread use.

9 May 2016

Unlocking cellular trap door may help in finding cures for many diseases

A team of researchers who two years ago announced a "Trojan horse" method of entering a cell without harming it have now found, in effect, the lock to the cellular "trap door."

6 May 2016

Female sex hormone estradiol may protect women against sexually transmitted viral infections

A team of researchers led by McMaster University's Charu Kaushic has revealed for the first time how estradiol, a female sex hormone present during the menstrual cycle and found in oral contraceptives, may work to protect women against sexually transmitted viral infections.

6 May 2016

Children infected with Cryptosporidium parasite more likely to suffer from stunted growth

Children infected even just once with a certain type of waterborne parasite are nearly three times as likely to suffer from moderate or severe stunted growth by the age of two than those who are not - regardless of whether their infection made them feel sick, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

5 May 2016

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Loss of appetite during illness is a common and potentially debilitating phenomenon--in cancer patients, especially, it can even shorten lifespan.

5 May 2016

Saliva fingerprints could be useful in searching for signs of disease

Testing for health conditions usually involves needles, X-rays and other invasive or uncomfortable measures. To make diagnostics less burdensome for patients, scientists are developing alternatives, looking for disease markers in urine -- and even spit.

5 May 2016

New study shows Ebola survivors may be at risk of severe vision loss

A new study has shown that Ebola survivors may be at risk of severe vision loss or blindness weeks after being declared virus-free. The research is being presented at the 2016 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Seattle, Wash.

5 May 2016

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall.

5 May 2016

Researchers highlight how BSI infecting pathogens become more resilient

A recently published special issue of Virulence, "Bloodstream Infections", focuses on the resilience of bloodstream infections (BSI) and is endorsed by the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases.

5 May 2016

Antiviral therapies equal survival rate of HCV-related cirrhosis patients with general population

The survival rate of patients with hepatitis C virus-related cirrhosis who respond well to antiviral therapies equals that of the general population, say investigators in the Journal of Hepatology.

5 May 2016

Finding treatments for rare diseases: an interview with Dr Richard Thompson

It is estimated that around 400 rare diseases have licenced treatments, and a large proportion of these are a consequence of orphan drug legislation, which has helped to incentivise the production of drugs for small patient populations.

4 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

The Cochrane Infectious Diseases Group have carried out a review update to evaluate the effects of corticosteroids being used alongside anti-tuberculosis medication to treat people suffering from tuberculous meningitis.

4 May 2016

Unfolding story of Zika virus in the Americas

Health Systems & Reform presents the article "Zika Virus and Health Systems in Brazil: From Unknown to a Menace," a commentary by Professor Marcia C. Castro, Department of Global Health and Population, Harvard T.H. Chan School of Public Health, on the Zika Virus epidemic in Brazil and the Americas.

4 May 2016

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent.

4 May 2016

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

A study has found that a syringe-like device used to invade intestinal cells also acts as a traffic cop -- directing bacteria where to go and thereby enabling them to efficiently carry out infection.

4 May 2016

Ebola vaccine shows promise in clinical trials

"The results for tolerability, safety, and the immune response to the vaccine candidate are very promising," explains Prof Marylyn Addo. The antibodies which developed against the virus were still detectable after six months. Addo is convinced, "With this, a single vaccine could provide lasting protection against Ebola." The infectious disease specialist, who works for the German Center for Infection Research at the University Medical Center Hamburg Eppendorf in Hamburg, led the trial in Hamburg.

4 May 2016

Disease/Infection News

Scientists develop low-cost, easy-to-use diagnostic platform to detect Zika virus

Study hints at new therapeutic approach to mitigate effects of prenatal Zika virus infection

New antibody-based therapy may provide better strategy for long-term control of HIV

MIT researchers develop innovative paper-based test to diagnose Zika virus

Unlocking cellular trap door may help in finding cures for many diseases

Female sex hormone estradiol may protect women against sexually transmitted viral infections

Children infected with Cryptosporidium parasite more likely to suffer from stunted growth

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Saliva fingerprints could be useful in searching for signs of disease

New study shows Ebola survivors may be at risk of severe vision loss

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers highlight how BSI infecting pathogens become more resilient

Antiviral therapies equal survival rate of HCV-related cirrhosis patients with general population

Finding treatments for rare diseases: an interview with Dr Richard Thompson

Candida yeast infections more common in men with schizophrenia or bipolar disorder

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

Unfolding story of Zika virus in the Americas

Scientists identify novel way of synthesising promising new antibiotic

Study shows syringe-like device acts as traffic cop directing bacteria to carry out infection

Ebola vaccine shows promise in clinical trials

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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