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Study shows epidermal growth factor negatively regulates shedding of epithelial cells

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders, ranging from inflammatory bowel disease (IBD) to colorectal cancer.

6 Apr 2016

Inflectra (infliximab-dyyb) approved for multiple indications

The U.S. Food and Drug Administration today approved Inflectra (infliximab-dyyb) for multiple indications. Inflectra is administered by intravenous infusion. This is the second biosimilar approved by the FDA.

6 Apr 2016

SymCel joins global initiative to combat antibiotic resistance

Following the global and joint initiative by the pharmaceutical, biotechnology and diagnostics industries this year to combat antibiotic resistance, demand for innovative solutions is especially high. The event took place in January at the World Economic Forum in Davos.

5 Apr 2016

Researchers find pathway to prevent emergence of zoonosis into human population

The parasite responsible for a form of malaria now spreading from macaques to humans in South Asia could evolve to infect humans more efficiently, a step towards enhanced transmission between humans, according to a new study from Harvard T.H. Chan School of Public Health. The researchers say that defining the means by which the Plasmodium knowlesi parasite invades red blood cells could lead to interventions to prevent the emergence of the zoonosis into the human population.

4 Apr 2016

Researchers develop novel vaccine strategy to protect against Chikungunya virus

The Chikungunya virus (CHIKV) is transmitted through mosquitoes and causes fever and joint pain that can sometimes become severe and disabling. Outbreaks of the virus have already occurred in Africa, Asia, and Europe, and in late 2013, the virus was first seen in the Americas with the number of cases dramatically increased. No vaccine to prevent or treat this virus currently exists.

2 Apr 2016

Seasonal trivalent influenza vaccination during pregnancy may guard against stillbirth

Seasonal influenza vaccination may guard against stillbirth, a new study published in Clinical Infectious Diseases and available online suggests. Researchers in Western Australia analyzed data from nearly 60,000 births that occurred during the southern hemisphere's 2012 and 2013 seasonal influenza epidemics, and found that women who received the trivalent influenza vaccine during pregnancy were 51 percent less likely to experience a stillbirth than unvaccinated mothers.

2 Apr 2016

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted.

2 Apr 2016

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.

2 Apr 2016

Investigators predict that new pneumonia epidemic in Beijing will likely to continue for longer time

Mycoplasma pneumoniae infections began rising in Beijing last spring, and by December, this pathogen was found in more than half of hospitalized children suffering from pneumonia in that city, according to investigators from the Capital Institute of Pediatrics, Beijing, China.

2 Apr 2016

GHIT Fund invests in two innovative malaria eradication tools

The Global Health Innovative Technology Fund (GHIT Fund) announced today that it’s investing US$1,383,785 in a pair of innovative malaria eradication tools—a vaccine that could block transmission of two species of the deadly disease and a rapid field test that can reveal a malaria infection in minutes.

1 Apr 2016

Experimental Ebola vaccine may help fight latest flare-up in Guinea

Hundreds of people who may have been in contact with 8 individuals infected with Ebola virus in Guinea’s southern prefectures of Nzérékoré and Macenta have been vaccinated with the experimental Ebola vaccine in a bid to contain the latest flare-up of Ebola.

1 Apr 2016

Johns Hopkins expert offers tips on Zika virus relating to pregnancy, sexual transmission

No treatment or vaccine currently exists for Zika virus. For most people who contract the virus, the illness will be mild and pass on its own in about one week.

1 Apr 2016

Purdue University-led researchers determine structure of Zika virus

A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which reveals insights critical to the development of effective antiviral treatments and vaccines.

1 Apr 2016

Researchers apply robust parameter selection, verification techniques to dynamic HIV model

Physical and biological models often have hundreds of inputs, many of which may have a negligible effect on a model's response. Establishing parameters that can be fixed at nominal values without significantly affecting model outputs is often challenging; sometimes these parameters cannot be simply discerned by the outputs.

1 Apr 2016

Study finds correlation between male sex hormones and oral health

More than 20 species of macaques, the most widely distributed nonhuman primates in the world, socialize in lively troops and make frequent appearances on National Geographic documentaries. But, what can we learn from one of our closest primate relatives about our own oral health?

31 Mar 2016

FDA announces availability of investigational test to screen donated blood for Zika virus

The U.S. Food and Drug Administration today announced the availability of an investigational test to screen blood donations for Zika virus. The screening test may be used under an investigational new drug application (IND) for screening donated blood in areas with active mosquito-borne transmission of Zika virus.

31 Mar 2016

NHS England to provide crucial funding for Janssen's HIV treatment, REZOLSTA

Janssen-Cilag Ltd today announced that NHS England will provide crucial funding for its once-daily, fixed-dose combination of darunavir and the pharmacoenhancer, cobicistat, called REZOLSTA.

31 Mar 2016

Abstracts on colistin resistance and migrant health part of 300 late-breaker sessions for ECCMID 2016

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores risks, knowledge sharing and best practices in the fight against infectious disease – has received more than 300 late-breaker abstract submissions for its annual congress, ECCMID 2016 in Amsterdam.

31 Mar 2016

Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

The risk in terms of the Olympics, especially for travelling populations remains low – with the notable exception of pregnant women.

31 Mar 2016

Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Communities of viruses can be transferred during fecal transplants, according to a study published this week in mBio, an online open-access journal of the American Society for Microbiology. Fortunately for patients who use this procedure, the viruses found to be transmitted in this study appear to be harmless to humans.

30 Mar 2016

Disease/Infection News

Study shows epidermal growth factor negatively regulates shedding of epithelial cells

Inflectra (infliximab-dyyb) approved for multiple indications

SymCel joins global initiative to combat antibiotic resistance

Researchers find pathway to prevent emergence of zoonosis into human population

Researchers develop novel vaccine strategy to protect against Chikungunya virus

Seasonal trivalent influenza vaccination during pregnancy may guard against stillbirth

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

Investigators predict that new pneumonia epidemic in Beijing will likely to continue for longer time

GHIT Fund invests in two innovative malaria eradication tools

Experimental Ebola vaccine may help fight latest flare-up in Guinea

Johns Hopkins expert offers tips on Zika virus relating to pregnancy, sexual transmission

Purdue University-led researchers determine structure of Zika virus

Researchers apply robust parameter selection, verification techniques to dynamic HIV model

Study finds correlation between male sex hormones and oral health

FDA announces availability of investigational test to screen donated blood for Zika virus

NHS England to provide crucial funding for Janssen's HIV treatment, REZOLSTA

Abstracts on colistin resistance and migrant health part of 300 late-breaker sessions for ECCMID 2016

Zika threat to Olympics attendees? An interview with Prof. Eskild Petersen

Fecal transplants transfer bacterial viruses that appear to be harmless to humans

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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