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Last resort antibiotics may no longer work

E.coli has become resistant to the last line of antibiotics we have left and untreatable bugs may already be circulating in Britain, warn scientists.

19 Nov 2015

New drug combination may reduce need for complex regimens to treat hepatitis C

The prognosis for people with hepatitis C has improved dramatically in the last few years, thanks to the introduction of direct-acting anti-viral medications, including Harvoni (the brand name for a combination of ledipasvir and sofosbuvir) and Viekira Pack (a mix of ombitasvir, paritaprevir, ritonavir and dasabuvir).

19 Nov 2015

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, West Africa and in the US, according to a study published in the latest issue of the journal Lancet Infectious Disease.

19 Nov 2015

HIV+ individuals show deficits in cognitive functioning

Neuroscientists at Georgetown University Medical Center have found in a small study that although a group of HIV+ older individuals scored "cognitively normal" in standard neuropsychology testing, a scan of their brains tells a different story.

19 Nov 2015

NIAID launches major initiative to advance novel approaches to treat, prevent HIV infections

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, launched a major initiative to advance novel approaches to treat and prevent HIV infections based on broadly neutralizing antibodies (bNAbs) today.

19 Nov 2015

Gamma interferon may have potential to prevent Ebola infection

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

18 Nov 2015

New NICE-accredited guidelines on prevention and control of MDRGNB available online

Gram-negative bacteria (MDRGNB) include common types such as E. coli that all of us carry in our bowels. When these bacteria get into other parts of the body they can cause infections, including common infections such as cystitis or urinary tract infections. The bacteria can also be readily spread from person to person. Multi-drug-resistant strains are resistant to most, or all, of the common antibiotics that we use to treat infections.

18 Nov 2015

British academics reveal psychological barriers behind HIV testing

Academics from Royal Holloway, University of London, have carried out the largest global review of psychological barriers behind HIV testing and the factors that may influence people's decision to be tested.

18 Nov 2015

Low vitamin D levels may limit effectiveness of HIV treatment

A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults.

18 Nov 2015

Discovery of new virus could pave way for stopping mosquito-borne disease outbreaks

Australian scientists have discovered a new virus carried by one of the country's most common pest mosquitoes. The new virus -- known as Parramatta River virus -- infects only mosquitoes and doesn't pose any direct health risks to people, according to University of Queensland (UQ) and University of Sydney researchers.

18 Nov 2015

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Tuberculosis has been infecting humans for several millennia, making it one of the most horribly successful diseases in history. Today, it is still a major killer, responsible for some 1.5 million deaths each year.

18 Nov 2015

Coating implants with certain 'activator' can prevent S. aureus infection

Biofilms frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can cause life-threatening infections. New research at the Sahlgrenska Academy show that coating implants with a certain "activator" can prevent Staphylococcus aureus, the leading cause of hospital-acquired infections, from forming biofilms.

18 Nov 2015

TSRI researchers have new weapons to combat HIV

Scientists at The Scripps Research Institute have new weapons in the fight against HIV. Their new study, published November 17, 2015 as the cover article of the journal Immunity, describes four prototype antibodies that target a specific weak spot on the virus. Guided by these antibodies, the researchers then mimicked the molecular structure of a protein on HIV when designing their own potential HIV vaccine candidate.

18 Nov 2015

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Immune Pharmaceuticals Inc. announced today that the first patient has been enrolled into the Phase 2 clinical trial evaluating the safety and efficacy of its first in class fully human monoclonal antibody, bertilimumab in Ulcerative Colitis (UC).

17 Nov 2015

Positive data from AbbVie's HCV clinical development program presented at The Liver Meeting of AASLD

AbbVie, a global biopharmaceutical company, today announced data from the SURVEYOR studies of its investigational HCV regimen, ABT-493, an NS3/4A protease inhibitor, and ABT-530, an NS5A inhibitor, that show high rates of sustained virologic response at 12 weeks post-treatment (SVR 12) in non-cirrhotic patients with chronic hepatitis C virus (HCV) infection.

17 Nov 2015

People confused about antibiotic resistance, shows WHO survey

As the World Health Organization ramps up its fight against antibiotic resistance, a new multi-country survey shows people are confused about this major threat to public health and do not understand how to prevent it from growing.

17 Nov 2015

Archbishop of York agrees to become Antibiotic Research UK's Patron

Antibiotic Research UK, a charity founded in 2014 to save modern medicine from the onslaught of superbugs, is delighted to announce that the Most Reverend & Right Honourable Dr John Sentamu, Archbishop of York has agreed to become the Charity’s Patron.

17 Nov 2015

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Nearly 50 percent of Medicaid patients infected with chronic hepatitis C whose doctors had prescribed newer, life-saving antiviral drugs were denied coverage to the therapies because they weren't considered "a medical necessity" or because the patients tested positive for alcohol/drugs, among other reasons, according to new Penn Medicine research.

17 Nov 2015

Study shows how parasitic worm infection increases susceptibility to TB

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tuberculosis (TB) that the parasite is known to cause.

17 Nov 2015

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

17 Nov 2015

Disease/Infection News

Last resort antibiotics may no longer work

New drug combination may reduce need for complex regimens to treat hepatitis C

Clinical study shows new Ebola vaccine stimulates strong immune responses in adults

HIV+ individuals show deficits in cognitive functioning

NIAID launches major initiative to advance novel approaches to treat, prevent HIV infections

Gamma interferon may have potential to prevent Ebola infection

New NICE-accredited guidelines on prevention and control of MDRGNB available online

British academics reveal psychological barriers behind HIV testing

Low vitamin D levels may limit effectiveness of HIV treatment

Discovery of new virus could pave way for stopping mosquito-borne disease outbreaks

TSRI scientists discover first-in-class compounds that target persistent tuberculosis

Coating implants with certain 'activator' can prevent S. aureus infection

TSRI researchers have new weapons to combat HIV

First patient enrolled in Phase 2 clinical trial of Immune's bertilimumab in Ulcerative Colitis

Positive data from AbbVie's HCV clinical development program presented at The Liver Meeting of AASLD

People confused about antibiotic resistance, shows WHO survey

Archbishop of York agrees to become Antibiotic Research UK's Patron

Nearly 50% of Medicaid patients infected with hepatitis C denied coverage for life-saving antiviral drugs

Study shows how parasitic worm infection increases susceptibility to TB

Birmingham researchers identify how Salmonella infections can lead to life-threatening thrombosis

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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